ENSG00000099860

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000215631 ENSG00000099860 No_inf pgKDN_inf GADD45B protein_coding protein_coding 9.635042 13.07744 6.750902 1.621476 0.4388051 -0.9528953 6.8786561 6.9404988 6.703992 0.5534439 0.4214245 -0.04994578 0.80343333 0.553475 0.993575 0.440100 2.251861e-07 2.251861e-07 FALSE TRUE
ENST00000587345 ENSG00000099860 No_inf pgKDN_inf GADD45B protein_coding protein_coding 9.635042 13.07744 6.750902 1.621476 0.4388051 -0.9528953 0.2218429 0.6655287 0.000000 0.6655287 0.0000000 -6.07794514 0.01747500 0.052425 0.000000 -0.052425 9.559356e-01 2.251861e-07 FALSE TRUE
ENST00000587887 ENSG00000099860 No_inf pgKDN_inf GADD45B protein_coding protein_coding 9.635042 13.07744 6.750902 1.621476 0.4388051 -0.9528953 1.8925275 3.6360500 0.000000 2.4493583 0.0000000 -8.51019052 0.12194167 0.236875 0.000000 -0.236875 6.090672e-01 2.251861e-07 FALSE FALSE
ENST00000593043 ENSG00000099860 No_inf pgKDN_inf GADD45B protein_coding protein_coding 9.635042 13.07744 6.750902 1.621476 0.4388051 -0.9528953 0.3509584 1.0528753 0.000000 0.6287237 0.0000000 -6.73182847 0.03133333 0.094000 0.000000 -0.094000 6.856681e-01 2.251861e-07 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099860 E001 0.0000000       19 2476122 2476126 5 +      
ENSG00000099860 E002 0.6076714 0.0151735878 0.34708863 0.63765292 19 2476127 2476145 19 + 0.282 0.144 -1.211
ENSG00000099860 E003 0.7263745 0.0136982632 0.17353472 0.44679068 19 2476146 2476147 2 + 0.346 0.144 -1.626
ENSG00000099860 E004 7.5903091 0.0022392254 0.06607831 0.25883271 19 2476148 2476355 208 + 1.018 0.852 -0.626
ENSG00000099860 E005 3.7050166 0.0041298591 0.78894541 0.91897246 19 2476356 2476402 47 + 0.638 0.676 0.163
ENSG00000099860 E006 0.0000000       19 2476403 2476431 29 +      
ENSG00000099860 E007 0.2537694 0.0162323365 0.43718052   19 2476432 2476528 97 + 0.000 0.144 9.609
ENSG00000099860 E008 9.1965829 0.0015520169 0.07748682 0.28483850 19 2476529 2476628 100 + 0.886 1.051 0.615
ENSG00000099860 E009 5.6033420 0.0026647621 0.07361468 0.27613952 19 2476629 2476630 2 + 0.667 0.875 0.834
ENSG00000099860 E010 0.5086410 0.2574874125 0.17924724 0.45434348 19 2476631 2477028 398 + 0.000 0.252 10.383
ENSG00000099860 E011 15.6172820 0.0009978392 0.13858622 0.39588375 19 2477029 2477251 223 + 1.139 1.244 0.374
ENSG00000099860 E012 0.6255163 0.0154362168 0.37531039 0.66284985 19 2477252 2477487 236 + 0.115 0.252 1.374
ENSG00000099860 E013 22.3253894 0.0008671156 0.01017398 0.08119615 19 2477488 2478259 772 + 1.429 1.303 -0.435

Help

Please Click HERE to learn more details about the results from DEXseq.