ENSG00000099917

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263205 ENSG00000099917 No_inf pgKDN_inf MED15 protein_coding protein_coding 70.21965 79.06012 60.49588 1.669288 2.375949 -0.3860574 7.699645 7.611036 7.7927509 2.2939323 1.1596620 0.03399566 0.11279167 0.098125 0.128950 0.030825 0.82199605 0.02182442 FALSE  
ENST00000292733 ENSG00000099917 No_inf pgKDN_inf MED15 protein_coding protein_coding 70.21965 79.06012 60.49588 1.669288 2.375949 -0.3860574 12.926083 11.634602 12.5656102 2.0434135 1.5299433 0.11096704 0.18670000 0.145875 0.208050 0.062175 0.63894002 0.02182442 FALSE  
ENST00000473244 ENSG00000099917 No_inf pgKDN_inf MED15 protein_coding retained_intron 70.21965 79.06012 60.49588 1.669288 2.375949 -0.3860574 4.304041 6.602960 1.7923554 1.3348366 0.4168353 -1.87541273 0.05946667 0.084150 0.029350 -0.054800 0.27042444 0.02182442 FALSE  
ENST00000489651 ENSG00000099917 No_inf pgKDN_inf MED15 protein_coding retained_intron 70.21965 79.06012 60.49588 1.669288 2.375949 -0.3860574 3.725513 7.883935 0.7180063 1.4033590 0.7180063 -3.43872184 0.04894167 0.098875 0.010725 -0.088150 0.02182442 0.02182442 FALSE  
MSTRG.19072.30 ENSG00000099917 No_inf pgKDN_inf MED15 protein_coding   70.21965 79.06012 60.49588 1.669288 2.375949 -0.3860574 4.946644 7.589856 3.3603068 0.2983632 0.2796263 -1.17309215 0.06868333 0.096175 0.055650 -0.040525 0.45065808 0.02182442 FALSE  
MSTRG.19072.33 ENSG00000099917 No_inf pgKDN_inf MED15 protein_coding   70.21965 79.06012 60.49588 1.669288 2.375949 -0.3860574 21.098827 21.120977 20.0657221 2.6533246 2.2794462 -0.07390757 0.30265000 0.266925 0.330025 0.063100 0.76600891 0.02182442 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099917 E001 0.5077596 1.503057e-02 1.148989e-01 3.573057e-01 22 20495913 20496036 124 + 0.000 0.254 11.450
ENSG00000099917 E002 1.3446564 1.019405e-02 3.132575e-01 6.064074e-01 22 20498679 20498791 113 + 0.449 0.299 -0.870
ENSG00000099917 E003 1.2513525 9.880313e-03 1.952499e-01 4.755084e-01 22 20499241 20499366 126 + 0.205 0.413 1.393
ENSG00000099917 E004 0.7453218 2.954945e-02 7.690642e-01 9.106682e-01 22 20500741 20500836 96 + 0.205 0.254 0.393
ENSG00000099917 E005 0.1268540 1.232772e-02 8.516410e-01   22 20507541 20507581 41 + 0.000 0.079 11.805
ENSG00000099917 E006 0.1268540 1.232772e-02 8.516410e-01   22 20507582 20507584 3 + 0.000 0.079 11.805
ENSG00000099917 E007 0.2533610 1.603950e-02 4.318207e-01   22 20507585 20507593 9 + 0.000 0.145 12.752
ENSG00000099917 E008 0.4992005 1.529078e-02 5.717540e-01   22 20507594 20507601 8 + 0.115 0.203 0.978
ENSG00000099917 E009 0.8706031 1.244990e-02 5.573834e-01 7.993791e-01 22 20507602 20507609 8 + 0.205 0.299 0.715
ENSG00000099917 E010 0.9971101 1.158659e-02 3.984121e-01 6.823221e-01 22 20507610 20507611 2 + 0.205 0.340 0.978
ENSG00000099917 E011 1.2508795 9.921044e-03 1.951997e-01 4.754744e-01 22 20507612 20507617 6 + 0.205 0.413 1.393
ENSG00000099917 E012 6.3670381 5.138397e-02 3.146543e-01 6.076202e-01 22 20507618 20507640 23 + 0.932 0.803 -0.496
ENSG00000099917 E013 17.2126045 9.142499e-04 2.328304e-01 5.214952e-01 22 20507641 20507735 95 + 1.295 1.217 -0.276
ENSG00000099917 E014 8.4857664 9.198005e-03 3.743211e-01 6.620302e-01 22 20507736 20507746 11 + 1.016 0.931 -0.314
ENSG00000099917 E015 0.0000000       22 20508048 20508056 9 +      
ENSG00000099917 E016 0.3549719 1.573675e-02 4.301275e-02   22 20508057 20508444 388 + 0.280 0.000 -14.812
ENSG00000099917 E017 2.5781844 4.046875e-02 4.903187e-01 7.529426e-01 22 20518878 20518995 118 + 0.604 0.503 -0.470
ENSG00000099917 E018 0.0000000       22 20523643 20523855 213 +      
ENSG00000099917 E019 0.0000000       22 20524275 20524286 12 +      
ENSG00000099917 E020 0.0000000       22 20524287 20524366 80 +      
ENSG00000099917 E021 17.7702960 1.231275e-03 1.992429e-02 1.267064e-01 22 20537117 20537204 88 + 1.351 1.195 -0.547
ENSG00000099917 E022 0.2539903 1.603844e-02 4.319432e-01   22 20537205 20537215 11 + 0.000 0.145 12.752
ENSG00000099917 E023 0.0000000       22 20550987 20551006 20 +      
ENSG00000099917 E024 0.0000000       22 20551007 20551166 160 +      
ENSG00000099917 E025 0.0000000       22 20551167 20551240 74 +      
ENSG00000099917 E026 0.0000000       22 20551241 20551289 49 +      
ENSG00000099917 E027 0.0000000       22 20551290 20551312 23 +      
ENSG00000099917 E028 0.0000000       22 20551313 20551347 35 +      
ENSG00000099917 E029 0.0000000       22 20551407 20551435 29 +      
ENSG00000099917 E030 18.1012044 8.039749e-04 3.809262e-01 6.673804e-01 22 20551436 20551487 52 + 1.302 1.247 -0.192
ENSG00000099917 E031 0.4907324 1.582978e-02 6.666864e-01   22 20551488 20551748 261 + 0.205 0.145 -0.607
ENSG00000099917 E032 0.6351783 3.275391e-02 6.559496e-02 2.580263e-01 22 20552539 20552709 171 + 0.000 0.299 13.913
ENSG00000099917 E033 0.0000000       22 20553097 20553144 48 +      
ENSG00000099917 E034 15.2805038 9.228818e-04 5.508539e-01 7.949074e-01 22 20553145 20553174 30 + 1.223 1.184 -0.138
ENSG00000099917 E035 0.3628435 1.671070e-02 3.489219e-01   22 20554239 20554935 697 + 0.205 0.079 -1.607
ENSG00000099917 E036 19.6895272 6.999719e-04 2.532424e-01 5.448004e-01 22 20554936 20554995 60 + 1.345 1.275 -0.245
ENSG00000099917 E037 20.9227529 6.880504e-03 3.254849e-01 6.179927e-01 22 20554996 20555076 81 + 1.368 1.302 -0.232
ENSG00000099917 E038 15.4818779 8.766316e-04 1.269299e-01 3.776387e-01 22 20555077 20555148 72 + 1.268 1.161 -0.378
ENSG00000099917 E039 23.9230785 5.748575e-04 8.540549e-06 2.987198e-04 22 20564450 20564688 239 + 1.527 1.266 -0.903
ENSG00000099917 E040 0.0000000       22 20566465 20566466 2 +      
ENSG00000099917 E041 43.7264711 8.423664e-04 1.071329e-04 2.512219e-03 22 20566467 20566817 351 + 1.736 1.565 -0.583
ENSG00000099917 E042 22.7229093 6.103250e-04 1.317394e-04 2.970416e-03 22 20568521 20568631 111 + 1.490 1.261 -0.794
ENSG00000099917 E043 63.0027192 2.509426e-04 5.836145e-09 4.311872e-07 22 20571466 20573677 2212 + 1.627 1.870 0.822
ENSG00000099917 E044 16.3298127 1.010990e-01 8.334689e-02 2.975220e-01 22 20573678 20573986 309 + 1.064 1.302 0.846
ENSG00000099917 E045 38.7489011 8.222150e-03 1.109176e-07 6.411822e-06 22 20573987 20574613 627 + 1.333 1.690 1.224
ENSG00000099917 E046 36.9704146 2.942083e-03 3.867335e-13 5.327548e-11 22 20574614 20575112 499 + 1.238 1.688 1.551
ENSG00000099917 E047 20.0834538 6.879224e-04 1.190256e-01 3.646217e-01 22 20575113 20575232 120 + 1.238 1.351 0.393
ENSG00000099917 E048 0.6338583 1.529274e-02 6.278603e-02 2.518633e-01 22 20579395 20579439 45 + 0.000 0.299 14.014
ENSG00000099917 E049 5.3886746 1.100847e-01 4.160818e-02 1.982592e-01 22 20581901 20582093 193 + 0.534 0.900 1.522
ENSG00000099917 E050 13.7741948 6.707680e-03 2.076733e-05 6.367626e-04 22 20582094 20582610 517 + 0.866 1.271 1.476
ENSG00000099917 E051 26.2935961 2.969105e-03 9.353016e-01 9.814116e-01 22 20582611 20582697 87 + 1.416 1.428 0.040
ENSG00000099917 E052 20.9976018 6.521472e-04 6.771712e-02 2.626577e-01 22 20582698 20582747 50 + 1.396 1.284 -0.387
ENSG00000099917 E053 0.4985712 3.383135e-02 5.752214e-01   22 20582748 20582839 92 + 0.115 0.203 0.978
ENSG00000099917 E054 20.0173802 7.467142e-04 8.331201e-02 2.974743e-01 22 20582840 20582863 24 + 1.374 1.266 -0.376
ENSG00000099917 E055 33.7894167 4.271497e-04 6.782685e-01 8.668041e-01 22 20582864 20582929 66 + 1.538 1.523 -0.053
ENSG00000099917 E056 26.0813406 5.881453e-04 6.844651e-01 8.693877e-01 22 20582930 20582967 38 + 1.401 1.431 0.104
ENSG00000099917 E057 0.2444846 1.635580e-02 7.354268e-01   22 20582968 20583112 145 + 0.115 0.079 -0.607
ENSG00000099917 E058 53.0718701 2.902344e-04 9.953916e-01 1.000000e+00 22 20583113 20583247 135 + 1.716 1.722 0.020
ENSG00000099917 E059 24.8786695 9.956505e-04 5.113521e-01 7.685426e-01 22 20583330 20583333 4 + 1.421 1.387 -0.117
ENSG00000099917 E060 26.4547908 5.207678e-04 2.372235e-01 5.261726e-01 22 20583334 20583337 4 + 1.464 1.401 -0.216
ENSG00000099917 E061 40.3010376 4.338573e-04 3.175307e-02 1.683612e-01 22 20583338 20583393 56 + 1.660 1.565 -0.325
ENSG00000099917 E062 4.9439665 1.018381e-02 8.294692e-01 9.382445e-01 22 20583394 20584358 965 + 0.743 0.775 0.130
ENSG00000099917 E063 36.8271339 4.900547e-04 2.615806e-01 5.543236e-01 22 20584359 20584425 67 + 1.595 1.545 -0.170
ENSG00000099917 E064 3.5999984 3.977959e-03 3.611689e-01 6.507473e-01 22 20584426 20584854 429 + 0.570 0.696 0.545
ENSG00000099917 E065 45.1747531 3.240659e-04 9.822397e-01 9.986073e-01 22 20584855 20584945 91 + 1.648 1.653 0.017
ENSG00000099917 E066 53.7551582 3.974204e-04 5.754936e-01 8.099651e-01 22 20584946 20585015 70 + 1.736 1.719 -0.058
ENSG00000099917 E067 3.3834701 4.665649e-03 2.145231e-02 1.326243e-01 22 20585016 20585100 85 + 0.400 0.729 1.530
ENSG00000099917 E068 83.4173595 7.417823e-04 4.792306e-01 7.450776e-01 22 20585101 20585267 167 + 1.894 1.925 0.104
ENSG00000099917 E069 6.2182024 2.757257e-02 1.494616e-01 4.117907e-01 22 20585268 20585727 460 + 0.718 0.911 0.756
ENSG00000099917 E070 58.0980608 2.635494e-04 9.650804e-02 3.235170e-01 22 20585728 20585826 99 + 1.795 1.735 -0.201
ENSG00000099917 E071 314.8953549 8.840333e-05 2.743333e-01 5.678717e-01 22 20586568 20587632 1065 + 2.493 2.482 -0.036

Help

Please Click HERE to learn more details about the results from DEXseq.