ENSG00000099956

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000407082 ENSG00000099956 No_inf pgKDN_inf SMARCB1 protein_coding protein_coding 39.19465 28.48843 47.40691 0.8361183 4.626703 0.7345194 2.293698 0.6239841 3.199788 0.6239841 3.1997877 2.33995925 0.0600250 0.020675 0.091000 0.070325 0.983784239 0.003933335 FALSE FALSE
ENST00000407422 ENSG00000099956 No_inf pgKDN_inf SMARCB1 protein_coding protein_coding 39.19465 28.48843 47.40691 0.8361183 4.626703 0.7345194 6.112976 5.4755983 6.573669 0.2297729 0.4985011 0.26324277 0.1660167 0.193050 0.143400 -0.049650 0.776940231 0.003933335 FALSE TRUE
ENST00000417137 ENSG00000099956 No_inf pgKDN_inf SMARCB1 protein_coding protein_coding 39.19465 28.48843 47.40691 0.8361183 4.626703 0.7345194 15.422718 15.1652018 15.289888 1.0756413 1.9764110 0.01180541 0.4174500 0.534250 0.321725 -0.212525 0.068405919 0.003933335 FALSE TRUE
ENST00000635578 ENSG00000099956 No_inf pgKDN_inf SMARCB1 protein_coding protein_coding 39.19465 28.48843 47.40691 0.8361183 4.626703 0.7345194 7.714985 0.0000000 15.752795 0.0000000 5.5174405 10.62230767 0.1494333 0.000000 0.304075 0.304075 0.003933335 0.003933335 FALSE FALSE
ENST00000646911 ENSG00000099956 No_inf pgKDN_inf SMARCB1 protein_coding retained_intron 39.19465 28.48843 47.40691 0.8361183 4.626703 0.7345194 5.153786 4.6294253 4.110117 0.7865236 0.8361968 -0.17126087 0.1381500 0.160975 0.086300 -0.074675 0.490364120 0.003933335 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099956 E001 0.0000000       22 23786931 23786962 32 +      
ENSG00000099956 E002 0.0000000       22 23786963 23786965 3 +      
ENSG00000099956 E003 0.2441377 0.0160419923 9.724031e-01   22 23786966 23786977 12 + 0.093 0.098 0.082
ENSG00000099956 E004 0.2441377 0.0160419923 9.724031e-01   22 23786978 23786979 2 + 0.093 0.098 0.082
ENSG00000099956 E005 0.4882753 0.4500764970 9.700881e-01   22 23786980 23786982 3 + 0.169 0.177 0.082
ENSG00000099956 E006 3.9915965 0.0036090095 7.339943e-02 0.275492881 22 23786983 23787000 18 + 0.795 0.576 -0.918
ENSG00000099956 E007 5.3408730 0.0029335817 1.753629e-01 0.449428541 22 23787001 23787010 10 + 0.871 0.723 -0.585
ENSG00000099956 E008 6.3316222 0.0024771413 3.448909e-01 0.635959573 22 23787011 23787016 6 + 0.910 0.816 -0.365
ENSG00000099956 E009 6.8224807 0.0032091620 3.716572e-01 0.659655811 22 23787017 23787026 10 + 0.935 0.848 -0.333
ENSG00000099956 E010 18.3840719 0.0007644091 7.547284e-02 0.280630984 22 23787027 23787181 155 + 1.341 1.227 -0.400
ENSG00000099956 E011 8.9084919 0.0058506480 5.466538e-01 0.792348683 22 23787182 23787201 20 + 1.022 0.969 -0.195
ENSG00000099956 E012 18.6552533 0.0007536738 2.032440e-01 0.485772413 22 23787202 23787257 56 + 1.332 1.252 -0.278
ENSG00000099956 E013 13.0626480 0.0132191383 4.681724e-01 0.736456682 22 23787258 23787262 5 + 1.177 1.117 -0.216
ENSG00000099956 E014 20.9186970 0.0008192410 8.048000e-01 0.927704012 22 23791756 23791800 45 + 1.346 1.335 -0.036
ENSG00000099956 E015 16.2201920 0.0014669098 2.243463e-01 0.511859506 22 23791801 23791810 10 + 1.275 1.193 -0.289
ENSG00000099956 E016 20.0628614 0.0007444119 8.538418e-01 0.948418858 22 23791811 23791867 57 + 1.327 1.320 -0.023
ENSG00000099956 E017 6.6495756 0.0023760597 2.135893e-01 0.498738478 22 23791868 23791894 27 + 0.811 0.945 0.513
ENSG00000099956 E018 1.6161707 0.0112862714 1.444106e-01 0.404555857 22 23791895 23793558 1664 + 0.290 0.514 1.252
ENSG00000099956 E019 32.0757295 0.0005663727 7.133916e-01 0.884507158 22 23793559 23793688 130 + 1.507 1.531 0.082
ENSG00000099956 E020 17.2390257 0.0024054596 3.723556e-02 0.185781224 22 23800944 23800970 27 + 1.177 1.330 0.540
ENSG00000099956 E021 33.2679717 0.0004437988 9.043865e-01 0.969262852 22 23800971 23801081 111 + 1.535 1.535 -0.003
ENSG00000099956 E022 0.9973622 0.0142246923 1.363982e-01 0.392849634 22 23801082 23801135 54 + 0.169 0.400 1.667
ENSG00000099956 E023 0.9986181 0.0121372800 1.354894e-01 0.391153710 22 23801136 23801298 163 + 0.169 0.400 1.667
ENSG00000099956 E024 3.4531621 0.1486295044 3.231794e-01 0.615851658 22 23801299 23801964 666 + 0.558 0.723 0.712
ENSG00000099956 E025 0.1272623 0.0123149918 5.150737e-01   22 23801965 23802000 36 + 0.000 0.098 10.971
ENSG00000099956 E026 2.0964236 0.0086269512 4.196909e-01 0.699158114 22 23802001 23802546 546 + 0.426 0.546 0.597
ENSG00000099956 E027 3.6704872 0.0081821679 9.063625e-01 0.970148349 22 23802547 23803294 748 + 0.660 0.679 0.082
ENSG00000099956 E028 35.3413066 0.0117929493 9.153382e-01 0.973494471 22 23803295 23803422 128 + 1.562 1.559 -0.007
ENSG00000099956 E029 0.7606477 0.0264908362 8.694825e-03 0.073248753 22 23803423 23804383 961 + 0.000 0.400 13.351
ENSG00000099956 E030 2.5586418 0.0149482717 5.908284e-01 0.818875919 22 23814991 23816624 1634 + 0.586 0.514 -0.333
ENSG00000099956 E031 0.3646036 0.0165081467 6.113897e-01   22 23816625 23816769 145 + 0.169 0.098 -0.918
ENSG00000099956 E032 37.0424899 0.0008056257 8.026860e-01 0.926528957 22 23816770 23816936 167 + 1.584 1.577 -0.022
ENSG00000099956 E033 1.5233436 0.0089603318 8.685048e-05 0.002115715 22 23816937 23818338 1402 + 0.000 0.604 14.276
ENSG00000099956 E034 0.3808443 0.0238381442 9.596688e-02   22 23818339 23818669 331 + 0.000 0.244 12.447
ENSG00000099956 E035 2.6026802 0.0137492295 1.107777e-01 0.349326892 22 23823108 23825224 2117 + 0.426 0.656 1.082
ENSG00000099956 E036 46.8655628 0.0003020027 1.588249e-01 0.425918074 22 23825225 23825415 191 + 1.646 1.711 0.218
ENSG00000099956 E037 2.2370605 0.1211140986 9.433838e-02 0.319681204 22 23825416 23826248 833 + 0.340 0.631 1.461
ENSG00000099956 E038 47.4820930 0.0003904791 9.446539e-01 0.984660748 22 23833572 23833703 132 + 1.684 1.687 0.008
ENSG00000099956 E039 54.2921353 0.0006029262 5.535855e-01 0.796703465 22 23834141 23838009 3869 + 1.751 1.734 -0.061

Help

Please Click HERE to learn more details about the results from DEXseq.