ENSG00000099991

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263119 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding protein_coding 36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 1.6604556 1.066326 1.2704475 0.6267882 0.8307424 0.2505333 0.07960833 0.014625 0.076950 0.062325 0.83428937 0.02998465 FALSE TRUE
ENST00000459824 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding retained_intron 36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 7.0526794 15.269577 2.6605519 1.7357903 0.8510847 -2.5163948 0.17619167 0.207050 0.141850 -0.065200 0.69557203 0.02998465   FALSE
ENST00000467937 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding retained_intron 36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 0.8695513 0.000000 1.4134513 0.0000000 0.8212652 7.1532494 0.04489167 0.000000 0.072450 0.072450 0.17553455 0.02998465 FALSE TRUE
ENST00000485008 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding protein_coding_CDS_not_defined 36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 5.3557171 11.838672 2.0767941 0.9078221 0.8577474 -2.5053652 0.13140000 0.161050 0.112525 -0.048525 0.75476460 0.02998465 FALSE TRUE
MSTRG.19159.14 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding   36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 5.4817848 10.494080 3.3545261 1.1178449 1.1709667 -1.6424745 0.16256667 0.144150 0.194250 0.050100 0.99623538 0.02998465 FALSE TRUE
MSTRG.19159.20 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding   36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 6.2913995 16.699456 0.7559789 0.9004021 0.7559789 -4.4472162 0.11230000 0.226500 0.040375 -0.186125 0.02998465 0.02998465 FALSE TRUE
MSTRG.19159.21 ENSG00000099991 No_inf pgKDN_inf CABIN1 protein_coding   36.61557 73.61384 18.21385 2.814485 1.112215 -2.014345 2.8023901 5.815922 1.7112333 1.1881149 1.0909816 -1.7590439 0.07190833 0.078950 0.086550 0.007600 0.84816368 0.02998465 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099991 E001 0.0000000       22 24011192 24011303 112 +      
ENSG00000099991 E002 0.0000000       22 24011304 24011314 11 +      
ENSG00000099991 E003 0.3723461 0.1469045539 7.049043e-01   22 24011315 24011347 33 + 0.154 0.108 -0.594
ENSG00000099991 E004 0.7423641 0.0196913780 6.586215e-01 8.573381e-01 22 24011348 24011367 20 + 0.267 0.194 -0.594
ENSG00000099991 E005 0.3809703 0.0218724428 5.590912e-01   22 24011416 24011417 2 + 0.000 0.153 12.250
ENSG00000099991 E006 1.1243382 0.1587613449 8.701614e-01 9.552531e-01 22 24011418 24011728 311 + 0.267 0.298 0.214
ENSG00000099991 E007 0.1187032 0.0117716829 1.538575e-01   22 24017508 24017551 44 + 0.154 0.000 -13.975
ENSG00000099991 E008 1.9301739 0.0081198586 3.081325e-04 5.928940e-03 22 24035444 24035520 77 + 0.754 0.232 -2.731
ENSG00000099991 E009 2.4129488 0.0206738800 5.689940e-05 1.483235e-03 22 24036089 24036181 93 + 0.842 0.266 -2.816
ENSG00000099991 E010 2.0695874 0.0105967399 3.962580e-03 4.214334e-02 22 24038348 24038461 114 + 0.720 0.298 -2.109
ENSG00000099991 E011 2.0812264 0.0894597060 3.735016e-02 1.861113e-01 22 24041139 24041273 135 + 0.684 0.328 -1.764
ENSG00000099991 E012 3.6214668 0.0042420520 3.581015e-07 1.837664e-05 22 24042904 24043084 181 + 0.997 0.356 -2.816
ENSG00000099991 E013 2.7542257 0.0290863775 6.923462e-07 3.354987e-05 22 24049091 24049220 130 + 0.937 0.232 -3.442
ENSG00000099991 E014 2.6763139 0.0053127309 8.776701e-04 1.357507e-02 22 24050825 24050974 150 + 0.815 0.356 -2.124
ENSG00000099991 E015 4.0236025 0.0072916507 4.532356e-04 8.091629e-03 22 24054873 24055067 195 + 0.937 0.493 -1.857
ENSG00000099991 E016 1.2120692 0.2601517803 9.267954e-02 3.162055e-01 22 24055068 24055159 92 + 0.550 0.194 -2.177
ENSG00000099991 E017 2.5391016 0.0054199039 7.822783e-05 1.935385e-03 22 24056192 24056360 169 + 0.842 0.298 -2.594
ENSG00000099991 E018 0.0000000       22 24056361 24056525 165 +      
ENSG00000099991 E019 2.3235065 0.0137170851 1.284574e-02 9.454450e-02 22 24059227 24059363 137 + 0.720 0.356 -1.746
ENSG00000099991 E020 4.1512418 0.0257769693 1.552378e-03 2.099974e-02 22 24059924 24060141 218 + 0.937 0.512 -1.764
ENSG00000099991 E021 1.0851877 0.0123515069 9.851236e-03 7.947892e-02 22 24061947 24062025 79 + 0.550 0.153 -2.594
ENSG00000099991 E022 2.1931998 0.0080999547 7.039753e-03 6.330144e-02 22 24062959 24063146 188 + 0.720 0.328 -1.916
ENSG00000099991 E023 3.5866306 0.0125446498 1.427160e-01 4.021284e-01 22 24064035 24064187 153 + 0.754 0.548 -0.883
ENSG00000099991 E024 1.2278083 0.0813534718 1.225694e-01 3.705216e-01 22 24066987 24067004 18 + 0.495 0.232 -1.595
ENSG00000099991 E025 4.0676705 0.0125973999 3.791419e-02 1.878780e-01 22 24067005 24067181 177 + 0.842 0.565 -1.153
ENSG00000099991 E026 2.9433032 0.0578069969 5.827387e-02 2.416786e-01 22 24070800 24070890 91 + 0.754 0.452 -1.353
ENSG00000099991 E027 2.4276079 0.0179440360 1.516634e-03 2.067176e-02 22 24070891 24071042 152 + 0.786 0.328 -2.179
ENSG00000099991 E028 0.2444846 0.0160954123 3.930926e-01   22 24071043 24071183 141 + 0.154 0.057 -1.594
ENSG00000099991 E029 2.3579046 0.0059228717 5.354266e-01 7.851681e-01 22 24072354 24072510 157 + 0.550 0.452 -0.478
ENSG00000099991 E030 2.3387156 0.0244479312 1.264720e-01 3.769044e-01 22 24076169 24076284 116 + 0.644 0.406 -1.134
ENSG00000099991 E031 2.2316527 0.0064115783 4.454107e-01 7.197621e-01 22 24083228 24083389 162 + 0.550 0.430 -0.594
ENSG00000099991 E032 3.6394526 0.0113354256 2.096215e-05 6.405511e-04 22 24084579 24084785 207 + 0.958 0.406 -2.382
ENSG00000099991 E033 3.1742824 0.0121838695 2.583181e-03 3.085684e-02 22 24085006 24085151 146 + 0.842 0.430 -1.816
ENSG00000099991 E034 3.7461658 0.0070394461 1.118241e-06 5.137240e-05 22 24087452 24087587 136 + 0.997 0.382 -2.664
ENSG00000099991 E035 4.0015431 0.0057518809 4.884522e-06 1.846123e-04 22 24087588 24087713 126 + 0.997 0.430 -2.401
ENSG00000099991 E036 0.1272623 0.0122612568 1.000000e+00   22 24087714 24087774 61 + 0.000 0.057 10.795
ENSG00000099991 E037 5.9992393 0.0563989464 6.286614e-03 5.838854e-02 22 24091583 24091843 261 + 1.049 0.655 -1.534
ENSG00000099991 E038 0.0000000       22 24091844 24092013 170 +      
ENSG00000099991 E039 5.5690818 0.0026926501 1.262163e-01 3.767154e-01 22 24095931 24096082 152 + 0.892 0.706 -0.736
ENSG00000099991 E040 4.4549953 0.0032034856 1.501503e-01 4.126265e-01 22 24098014 24098105 92 + 0.815 0.627 -0.771
ENSG00000099991 E041 1.8601850 0.0074439844 4.855843e-01 7.493849e-01 22 24098106 24098112 7 + 0.495 0.382 -0.594
ENSG00000099991 E042 3.9088103 0.0036153523 8.458617e-04 1.318137e-02 22 24098113 24098192 80 + 0.915 0.493 -1.775
ENSG00000099991 E043 0.0000000       22 24098193 24098282 90 +      
ENSG00000099991 E044 10.1452494 0.0014545794 7.237661e-08 4.361520e-06 22 24113566 24113748 183 + 1.295 0.813 -1.768
ENSG00000099991 E045 13.9522299 0.0010157918 1.357920e-08 9.413632e-07 22 24119367 24119698 332 + 1.402 0.956 -1.594
ENSG00000099991 E046 5.5426481 0.0197762669 4.716933e-02 2.133490e-01 22 24134302 24134415 114 + 0.937 0.682 -1.009
ENSG00000099991 E047 0.8609062 0.1935803434 3.617325e-01 6.511052e-01 22 24155783 24155837 55 + 0.357 0.194 -1.178
ENSG00000099991 E048 5.8845624 0.0024321516 3.274814e-01 6.200372e-01 22 24155838 24156076 239 + 0.684 0.803 0.484
ENSG00000099991 E049 1.0071462 0.0910337716 4.246822e-01 7.038821e-01 22 24156384 24156532 149 + 0.154 0.298 1.214
ENSG00000099991 E050 0.6152606 0.0157121521 4.707059e-01 7.383197e-01 22 24156533 24156576 44 + 0.267 0.153 -1.009
ENSG00000099991 E051 1.3957646 0.0641257694 3.553331e-02 1.805420e-01 22 24160106 24160262 157 + 0.000 0.406 13.796
ENSG00000099991 E052 0.6347699 0.0382978253 2.404328e-01 5.296749e-01 22 24160263 24160329 67 + 0.000 0.232 12.874
ENSG00000099991 E053 1.0152673 0.0429789518 8.343272e-02 2.976492e-01 22 24160330 24160406 77 + 0.000 0.328 13.449
ENSG00000099991 E054 1.0150495 0.1528364621 1.184556e-01 3.635567e-01 22 24162006 24162065 60 + 0.000 0.328 13.286
ENSG00000099991 E055 0.8882570 0.0121186436 1.097400e-01 3.476684e-01 22 24162066 24162104 39 + 0.000 0.298 13.346
ENSG00000099991 E056 1.2692887 0.0097265550 3.857244e-02 1.899357e-01 22 24162105 24162215 111 + 0.000 0.382 13.781
ENSG00000099991 E057 21.1320729 0.0007120931 1.672407e-01 4.377985e-01 22 24164400 24164563 164 + 1.201 1.298 0.343
ENSG00000099991 E058 14.6883019 0.0042020933 1.243218e-02 9.244690e-02 22 24165530 24165626 97 + 0.937 1.175 0.865
ENSG00000099991 E059 78.3884019 0.0009341382 3.675676e-02 1.845674e-01 22 24166639 24167222 584 + 1.770 1.846 0.258
ENSG00000099991 E060 23.6684433 0.0006157874 4.294295e-02 2.020985e-01 22 24167223 24167313 91 + 1.212 1.353 0.494
ENSG00000099991 E061 1.1261625 0.0151041159 8.375446e-01 9.418067e-01 22 24168432 24168446 15 + 0.267 0.298 0.213
ENSG00000099991 E062 24.6600024 0.0006459111 4.733687e-02 2.137531e-01 22 24168447 24168521 75 + 1.235 1.369 0.471
ENSG00000099991 E063 67.4953945 0.0002360575 4.631984e-04 8.229109e-03 22 24171713 24171995 283 + 1.651 1.795 0.488
ENSG00000099991 E064 10.0577242 0.0014329770 1.211377e-02 9.107940e-02 22 24173077 24173398 322 + 0.754 1.030 1.055
ENSG00000099991 E065 17.0921736 0.0017741951 3.054730e-03 3.494589e-02 22 24175779 24176110 332 + 0.978 1.239 0.942
ENSG00000099991 E066 41.8525992 0.0003534179 1.240925e-03 1.765912e-02 22 24176111 24176275 165 + 1.424 1.598 0.597
ENSG00000099991 E067 4.1527713 0.0287485707 8.218322e-02 2.951045e-01 22 24176276 24176506 231 + 0.431 0.706 1.264
ENSG00000099991 E068 22.9853027 0.0006444625 5.224812e-04 9.031892e-03 22 24177504 24177590 87 + 1.096 1.361 0.937
ENSG00000099991 E069 56.2461214 0.0003128948 4.689964e-04 8.315205e-03 22 24177591 24177817 227 + 1.560 1.721 0.547
ENSG00000099991 E070 108.3595423 0.0002391056 1.142579e-06 5.235670e-05 22 24178053 24178628 576 + 1.844 2.000 0.524

Help

Please Click HERE to learn more details about the results from DEXseq.