ENSG00000100055

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000248901 ENSG00000100055 No_inf pgKDN_inf CYTH4 protein_coding protein_coding 160.8652 137.748 174.6581 2.520608 4.836956 0.3424805 84.283423 54.49715 109.049217 4.7383662 2.4118356 1.0005942 0.5167583 0.397550 0.626300 0.228750 0.001841123 0.001841123 FALSE TRUE
ENST00000446506 ENSG00000100055 No_inf pgKDN_inf CYTH4 protein_coding protein_coding 160.8652 137.748 174.6581 2.520608 4.836956 0.3424805 28.893495 36.34577 24.779425 4.6050311 3.4218246 -0.5524595 0.1841750 0.262300 0.140600 -0.121700 0.056166260 0.001841123 FALSE FALSE
ENST00000462927 ENSG00000100055 No_inf pgKDN_inf CYTH4 protein_coding retained_intron 160.8652 137.748 174.6581 2.520608 4.836956 0.3424805 17.616011 20.02239 13.957402 0.8970833 0.2829786 -0.5202711 0.1120583 0.145575 0.080100 -0.065475 0.055898905 0.001841123 TRUE TRUE
ENST00000469886 ENSG00000100055 No_inf pgKDN_inf CYTH4 protein_coding retained_intron 160.8652 137.748 174.6581 2.520608 4.836956 0.3424805 7.988746 10.34213 5.948668 0.2461011 0.6368855 -0.7968659 0.0515250 0.075250 0.034225 -0.041025 0.112361924 0.001841123 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100055 E001 0.2545247 2.992649e-01 2.590642e-01   22 37282027 37282196 170 + 0.000 0.184 9.697
ENSG00000100055 E002 0.1186381 1.185728e-02 6.224865e-01   22 37282441 37282474 34 + 0.089 0.000 -11.748
ENSG00000100055 E003 0.5906791 1.443412e-02 3.058396e-02 1.645778e-01 22 37282475 37282486 12 + 0.330 0.000 -13.991
ENSG00000100055 E004 5.4345599 3.172733e-03 4.078327e-02 1.959616e-01 22 37282487 37282507 21 + 0.905 0.671 -0.931
ENSG00000100055 E005 6.0337345 2.297827e-03 1.999004e-02 1.269403e-01 22 37282508 37282514 7 + 0.952 0.695 -1.007
ENSG00000100055 E006 8.7305673 1.591349e-02 1.749668e-01 4.488037e-01 22 37282515 37282524 10 + 1.050 0.910 -0.522
ENSG00000100055 E007 8.8481979 1.738696e-02 1.525787e-01 4.166604e-01 22 37282525 37282526 2 + 1.059 0.910 -0.553
ENSG00000100055 E008 10.0904506 3.242195e-02 4.042912e-01 6.870976e-01 22 37282527 37282530 4 + 1.084 0.998 -0.312
ENSG00000100055 E009 28.3979479 1.142520e-02 5.340601e-01 7.843158e-01 22 37282531 37282588 58 + 1.488 1.446 -0.146
ENSG00000100055 E010 0.7263069 2.810391e-02 5.280170e-01 7.798579e-01 22 37282966 37283041 76 + 0.281 0.184 -0.785
ENSG00000100055 E011 1.2245400 1.101241e-02 8.185287e-01 9.339397e-01 22 37283998 37284110 113 + 0.330 0.365 0.215
ENSG00000100055 E012 2.4950543 5.764151e-03 9.973815e-03 8.010838e-02 22 37292144 37292620 477 + 0.330 0.695 1.800
ENSG00000100055 E013 67.6242352 2.701798e-04 1.252654e-01 3.751701e-01 22 37292621 37292703 83 + 1.862 1.806 -0.187
ENSG00000100055 E014 75.0985049 2.123401e-04 2.465787e-04 4.973404e-03 22 37294660 37294724 65 + 1.938 1.810 -0.430
ENSG00000100055 E015 76.7037807 1.984358e-04 9.335630e-04 1.423545e-02 22 37295999 37296065 67 + 1.941 1.827 -0.383
ENSG00000100055 E016 2.7132875 5.169195e-03 2.363906e-01 5.254313e-01 22 37296066 37296603 538 + 0.483 0.646 0.746
ENSG00000100055 E017 112.1467627 1.664523e-04 6.803341e-04 1.109895e-02 22 37297564 37297682 119 + 2.097 2.001 -0.323
ENSG00000100055 E018 30.2308265 6.400500e-04 1.049095e-09 8.896523e-08 22 37297683 37298402 720 + 1.298 1.638 1.171
ENSG00000100055 E019 75.9065659 2.026528e-04 4.779408e-03 4.797554e-02 22 37299226 37299306 81 + 1.930 1.832 -0.327
ENSG00000100055 E020 4.1899816 1.662457e-01 3.863938e-01 6.722939e-01 22 37300070 37300152 83 + 0.621 0.798 0.732
ENSG00000100055 E021 34.5485976 5.988447e-04 1.906477e-06 8.154158e-05 22 37300153 37300881 729 + 1.415 1.661 0.844
ENSG00000100055 E022 5.0168095 1.009618e-02 7.636606e-01 9.078471e-01 22 37300882 37300906 25 + 0.761 0.798 0.145
ENSG00000100055 E023 87.8696289 7.150241e-04 1.084820e-02 8.482223e-02 22 37300907 37301019 113 + 1.987 1.902 -0.285
ENSG00000100055 E024 1.2257584 2.654848e-02 8.211776e-01 9.350721e-01 22 37301881 37301934 54 + 0.330 0.365 0.216
ENSG00000100055 E025 1.4728340 1.143985e-01 8.100244e-01 9.298850e-01 22 37301935 37302031 97 + 0.374 0.412 0.215
ENSG00000100055 E026 105.7528501 1.563216e-04 4.653568e-02 2.117359e-01 22 37303254 37303402 149 + 2.055 1.997 -0.193
ENSG00000100055 E027 18.6617509 2.214107e-03 7.891688e-05 1.950790e-03 22 37304172 37304286 115 + 1.137 1.416 0.978
ENSG00000100055 E028 96.1705478 2.971567e-03 7.997840e-01 9.249212e-01 22 37309212 37309323 112 + 1.982 1.993 0.036
ENSG00000100055 E029 3.0657793 1.128310e-01 7.484614e-01 9.006886e-01 22 37309968 37310032 65 + 0.571 0.646 0.330
ENSG00000100055 E030 91.2488689 1.821015e-04 8.254683e-01 9.368265e-01 22 37310988 37311064 77 + 1.961 1.969 0.026
ENSG00000100055 E031 113.9572372 1.644896e-04 3.131000e-01 6.063941e-01 22 37311456 37311527 72 + 2.046 2.075 0.098
ENSG00000100055 E032 59.7303442 2.407880e-04 6.473736e-14 9.891062e-12 22 37311528 37312019 492 + 1.615 1.912 1.005
ENSG00000100055 E033 175.2467291 1.913922e-03 1.371160e-01 3.941795e-01 22 37312020 37312174 155 + 2.225 2.267 0.143
ENSG00000100055 E034 1344.3338175 4.581675e-05 4.820114e-01 7.469916e-01 22 37313439 37315341 1903 + 3.126 3.131 0.017

Help

Please Click HERE to learn more details about the results from DEXseq.