ENSG00000100083

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325180 ENSG00000100083 No_inf pgKDN_inf GGA1 protein_coding protein_coding 44.37039 27.39925 45.89894 0.8525299 1.431509 0.744112 2.488918 1.537694 4.2902027 0.4545780 2.6902656 1.4742841 0.06071667 0.057725 0.096025 0.038300 0.98680003 0.04321403 FALSE TRUE
ENST00000343632 ENSG00000100083 No_inf pgKDN_inf GGA1 protein_coding protein_coding 44.37039 27.39925 45.89894 0.8525299 1.431509 0.744112 24.981537 11.174340 30.2074130 0.6700605 3.1108752 1.4339000 0.54244167 0.407725 0.656300 0.248575 0.04321403 0.04321403 FALSE TRUE
ENST00000460957 ENSG00000100083 No_inf pgKDN_inf GGA1 protein_coding retained_intron 44.37039 27.39925 45.89894 0.8525299 1.431509 0.744112 0.493959 1.481877 0.0000000 1.0617476 0.0000000 -7.2209847 0.01743333 0.052300 0.000000 -0.052300 0.40953535 0.04321403   FALSE
ENST00000463672 ENSG00000100083 No_inf pgKDN_inf GGA1 protein_coding retained_intron 44.37039 27.39925 45.89894 0.8525299 1.431509 0.744112 2.814425 1.372975 0.5889456 0.4624053 0.5889456 -1.2072778 0.05607500 0.051600 0.011875 -0.039725 0.40599060 0.04321403   FALSE
MSTRG.19363.2 ENSG00000100083 No_inf pgKDN_inf GGA1 protein_coding   44.37039 27.39925 45.89894 0.8525299 1.431509 0.744112 5.773258 5.453842 4.8486874 0.2219396 0.3421608 -0.1693491 0.14074167 0.198900 0.105875 -0.093025 0.27108616 0.04321403 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100083 E001 0.0000000       22 37608725 37608750 26 +      
ENSG00000100083 E002 0.1271363 0.0123421514 3.321112e-01   22 37608751 37608829 79 + 0.000 0.117 11.409
ENSG00000100083 E003 0.1186381 0.0117831281 8.872759e-01   22 37608830 37608833 4 + 0.077 0.000 -13.449
ENSG00000100083 E004 0.1186381 0.0117831281 8.872759e-01   22 37608834 37608834 1 + 0.077 0.000 -13.449
ENSG00000100083 E005 0.3532727 0.0157461755 2.282010e-01   22 37608835 37608844 10 + 0.199 0.000 -14.918
ENSG00000100083 E006 7.2159713 0.0022334412 2.684912e-02 1.521093e-01 22 37608845 37608903 59 + 0.988 0.750 -0.916
ENSG00000100083 E007 0.0000000       22 37608935 37608947 13 +      
ENSG00000100083 E008 0.1186381 0.0117831281 8.872759e-01   22 37608948 37608959 12 + 0.077 0.000 -13.449
ENSG00000100083 E009 0.1186381 0.0117831281 8.872759e-01   22 37608960 37608976 17 + 0.077 0.000 -13.449
ENSG00000100083 E010 0.1186381 0.0117831281 8.872759e-01   22 37608977 37608983 7 + 0.077 0.000 -13.449
ENSG00000100083 E011 0.1186381 0.0117831281 8.872759e-01   22 37608984 37609039 56 + 0.077 0.000 -13.449
ENSG00000100083 E012 0.2537694 0.0160628259 1.202353e-01   22 37609040 37609059 20 + 0.000 0.209 14.448
ENSG00000100083 E013 0.2537694 0.0160628259 1.202353e-01   22 37609060 37609065 6 + 0.000 0.209 14.448
ENSG00000100083 E014 0.3724725 0.0166102308 3.365440e-01   22 37609066 37609154 89 + 0.077 0.209 1.669
ENSG00000100083 E015 0.7448488 0.0140078776 1.697056e-01 4.417887e-01 22 37609155 37609356 202 + 0.142 0.349 1.669
ENSG00000100083 E016 0.2545247 0.2263135544 1.566101e-01   22 37610142 37610486 345 + 0.000 0.209 13.894
ENSG00000100083 E017 0.7352171 0.0143961592 5.763995e-01 8.104891e-01 22 37610577 37610699 123 + 0.199 0.285 0.669
ENSG00000100083 E018 1.7237988 0.0078934077 1.667858e-01 4.372202e-01 22 37612536 37613023 488 + 0.335 0.540 1.084
ENSG00000100083 E019 0.2533610 0.0160448383 1.202448e-01   22 37613024 37613032 9 + 0.000 0.209 14.448
ENSG00000100083 E020 0.7325141 0.0634226686 5.873152e-01 8.169037e-01 22 37613033 37613118 86 + 0.199 0.285 0.669
ENSG00000100083 E021 0.7329225 0.0639312126 5.872376e-01 8.168800e-01 22 37613119 37613191 73 + 0.199 0.285 0.669
ENSG00000100083 E022 0.0000000       22 37613970 37614032 63 +      
ENSG00000100083 E023 0.2457744 0.0163457417 7.184582e-01   22 37614133 37614189 57 + 0.077 0.117 0.669
ENSG00000100083 E024 7.5883787 0.0019405214 5.366486e-02 2.306447e-01 22 37614190 37614193 4 + 0.997 0.796 -0.767
ENSG00000100083 E025 15.6426556 0.0012301977 2.867858e-03 3.339271e-02 22 37614194 37614274 81 + 1.293 1.060 -0.829
ENSG00000100083 E026 11.9337168 0.0034661274 5.955873e-02 2.447235e-01 22 37616922 37616997 76 + 1.164 0.998 -0.603
ENSG00000100083 E027 4.0615926 0.0037880443 2.988410e-02 1.626079e-01 22 37616998 37617048 51 + 0.570 0.837 1.109
ENSG00000100083 E028 40.6319087 0.0003584477 7.139540e-12 8.263175e-10 22 37617049 37618402 1354 + 1.456 1.771 1.073
ENSG00000100083 E029 2.7015758 0.0083908579 1.389193e-01 3.963432e-01 22 37618403 37618447 45 + 0.469 0.672 0.932
ENSG00000100083 E030 19.3003201 0.0044304877 1.367628e-02 9.853276e-02 22 37618448 37618546 99 + 1.364 1.182 -0.641
ENSG00000100083 E031 2.3579107 0.0064935795 9.619629e-03 7.836200e-02 22 37619800 37620237 438 + 0.335 0.700 1.784
ENSG00000100083 E032 29.1241446 0.0048680080 3.663327e-02 1.841531e-01 22 37620238 37620361 124 + 1.519 1.388 -0.450
ENSG00000100083 E033 16.0975159 0.0041920195 2.761945e-01 5.696691e-01 22 37620813 37620853 41 + 1.257 1.173 -0.299
ENSG00000100083 E034 21.0455067 0.0009485433 1.487841e-01 4.108606e-01 22 37620854 37620913 60 + 1.371 1.276 -0.331
ENSG00000100083 E035 24.4046751 0.0011773243 9.593713e-01 9.904193e-01 22 37621616 37621696 81 + 1.396 1.399 0.012
ENSG00000100083 E036 37.0867626 0.0003614782 2.704956e-01 5.642087e-01 22 37623327 37623467 141 + 1.594 1.540 -0.185
ENSG00000100083 E037 23.0101814 0.0007031275 2.666745e-01 5.600788e-01 22 37623552 37623633 82 + 1.399 1.330 -0.241
ENSG00000100083 E038 0.6175864 0.0147305524 3.392200e-01 6.309225e-01 22 37623634 37623828 195 + 0.142 0.285 1.254
ENSG00000100083 E039 5.1935828 0.0030499091 9.092488e-04 1.394750e-02 22 37623829 37624968 1140 + 0.592 0.970 1.517
ENSG00000100083 E040 33.8724671 0.0057636054 8.774668e-01 9.584351e-01 22 37624969 37625076 108 + 1.539 1.528 -0.038
ENSG00000100083 E041 29.3046157 0.0012975032 6.066337e-01 8.288330e-01 22 37625797 37625949 153 + 1.462 1.490 0.099
ENSG00000100083 E042 6.9405983 0.0053124538 5.549036e-05 1.454273e-03 22 37625950 37627162 1213 + 0.671 1.094 1.630
ENSG00000100083 E043 16.8095072 0.0008973838 3.226440e-01 6.155895e-01 22 37629462 37629526 65 + 1.213 1.283 0.248
ENSG00000100083 E044 33.7101743 0.0066296540 4.314610e-01 7.092228e-01 22 37629998 37630170 173 + 1.551 1.503 -0.163
ENSG00000100083 E045 1.3630005 0.0105875589 9.805849e-02 3.265831e-01 22 37630171 37630299 129 + 0.250 0.500 1.476
ENSG00000100083 E046 2.0686753 0.0419327554 8.397714e-01 9.425671e-01 22 37630395 37630667 273 + 0.469 0.500 0.154
ENSG00000100083 E047 1.3519534 0.0172944611 2.960923e-01 5.891541e-01 22 37630668 37630902 235 + 0.295 0.455 0.932
ENSG00000100083 E048 45.0349031 0.0003805279 6.408871e-01 8.475909e-01 22 37630903 37631099 197 + 1.663 1.642 -0.070
ENSG00000100083 E049 44.5356826 0.0003716592 5.284266e-01 7.801907e-01 22 37631996 37632165 170 + 1.661 1.633 -0.096
ENSG00000100083 E050 32.1149597 0.0006455651 3.738454e-01 6.615584e-01 22 37632405 37632515 111 + 1.493 1.540 0.161
ENSG00000100083 E051 0.3726284 0.0166208173 3.364523e-01   22 37632516 37632600 85 + 0.077 0.209 1.669
ENSG00000100083 E052 145.8882184 0.0001780037 4.985459e-01 7.589854e-01 22 37632601 37633652 1052 + 2.165 2.150 -0.052

Help

Please Click HERE to learn more details about the results from DEXseq.