ENSG00000100105

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000215919 ENSG00000100105 No_inf pgKDN_inf PATZ1 protein_coding protein_coding 6.543949 9.356228 4.696397 0.4319252 0.2155445 -0.992845 0.5625577 0.0000000 0.8748571 0.0000000 0.3487395 6.4673725 0.1120750 0.000000 0.190075 0.190075 0.03491823 0.03491823 FALSE TRUE
ENST00000266269 ENSG00000100105 No_inf pgKDN_inf PATZ1 protein_coding protein_coding 6.543949 9.356228 4.696397 0.4319252 0.2155445 -0.992845 0.6325216 0.3238917 0.3863606 0.3238917 0.2360507 0.2474330 0.1114833 0.032875 0.079900 0.047025 0.76945857 0.03491823 FALSE TRUE
ENST00000351933 ENSG00000100105 No_inf pgKDN_inf PATZ1 protein_coding protein_coding 6.543949 9.356228 4.696397 0.4319252 0.2155445 -0.992845 3.0697357 4.5769678 2.5905964 0.4974179 0.4745419 -0.8186983 0.4674583 0.496300 0.559075 0.062775 0.90499406 0.03491823 FALSE TRUE
ENST00000405309 ENSG00000100105 No_inf pgKDN_inf PATZ1 protein_coding protein_coding 6.543949 9.356228 4.696397 0.4319252 0.2155445 -0.992845 0.8418025 1.3853529 0.4889881 0.6517575 0.4889881 -1.4835529 0.1235250 0.143150 0.099350 -0.043800 0.77938393 0.03491823 FALSE TRUE
ENST00000465287 ENSG00000100105 No_inf pgKDN_inf PATZ1 protein_coding retained_intron 6.543949 9.356228 4.696397 0.4319252 0.2155445 -0.992845 1.3661582 2.9936908 0.2734277 0.1669533 0.2734277 -3.4056837 0.1734667 0.319525 0.052650 -0.266875 0.08367954 0.03491823   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100105 E001 0.1265070 0.0123698473 1.000000000   22 31325804 31325808 5 - 0.000 0.071 8.360
ENSG00000100105 E002 55.9207765 0.0086873635 0.055826325 0.23541337 22 31325809 31327309 1501 - 1.668 1.756 0.298
ENSG00000100105 E003 1.2526392 0.0255812379 0.341792135 0.63328239 22 31328787 31328859 73 - 0.224 0.384 1.076
ENSG00000100105 E004 0.7356603 0.0145615478 0.421201123 0.70036552 22 31328860 31328924 65 - 0.304 0.186 -0.924
ENSG00000100105 E005 0.2448930 0.0165037947 0.602399014   22 31335418 31335691 274 - 0.126 0.071 -0.924
ENSG00000100105 E006 9.6360360 0.0754009513 0.646015874 0.85021097 22 31335692 31335863 172 - 1.032 0.987 -0.167
ENSG00000100105 E007 16.9444139 0.0008496503 0.047326092 0.21372676 22 31340677 31341683 1007 - 1.119 1.273 0.550
ENSG00000100105 E008 6.3868543 0.0025815906 0.065133316 0.25702837 22 31342897 31342960 64 - 0.959 0.776 -0.702
ENSG00000100105 E009 0.3810317 0.0278295536 0.313401559   22 31342961 31343591 631 - 0.000 0.186 11.373
ENSG00000100105 E010 35.8738286 0.0005753546 0.003707381 0.04029734 22 31344332 31346346 2015 - 1.614 1.499 -0.393

Help

Please Click HERE to learn more details about the results from DEXseq.