ENSG00000100201

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000216019 ENSG00000100201 No_inf pgKDN_inf DDX17 protein_coding retained_intron 157.1902 209.474 131.642 1.687419 1.015751 -0.6701105 25.40537 39.14163 17.342834 0.2340359 0.4213345 -1.17390103 0.15663333 0.186900 0.131775 -0.055125 1.964603e-01 2.438218e-08 TRUE TRUE
ENST00000403230 ENSG00000100201 No_inf pgKDN_inf DDX17 protein_coding protein_coding 157.1902 209.474 131.642 1.687419 1.015751 -0.6701105 81.97699 87.25382 83.238518 2.4493457 1.6501941 -0.06795901 0.54239167 0.416675 0.632250 0.215575 2.438218e-08 2.438218e-08 FALSE TRUE
MSTRG.19398.1 ENSG00000100201 No_inf pgKDN_inf DDX17 protein_coding   157.1902 209.474 131.642 1.687419 1.015751 -0.6701105 13.00971 24.78916 8.904218 2.2800530 1.6259036 -1.47611139 0.07563333 0.118200 0.067550 -0.050650 3.059161e-01 2.438218e-08 TRUE TRUE
MSTRG.19398.4 ENSG00000100201 No_inf pgKDN_inf DDX17 protein_coding   157.1902 209.474 131.642 1.687419 1.015751 -0.6701105 33.70844 54.77818 20.115610 0.9451634 0.7902528 -1.44483222 0.20516667 0.261600 0.152900 -0.108700 3.024671e-03 2.438218e-08 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100201 E001 0.0000000       22 38483438 38483439 2 -      
ENSG00000100201 E002 2259.7894071 4.471765e-05 3.846621e-04 7.075841e-03 22 38483440 38485394 1955 - 3.342 3.320 -0.072
ENSG00000100201 E003 173.5032353 2.641863e-04 3.590349e-01 6.485300e-01 22 38485395 38485676 282 - 2.231 2.206 -0.083
ENSG00000100201 E004 29.2968189 4.697740e-04 2.944644e-01 5.878824e-01 22 38485677 38485680 4 - 1.414 1.474 0.205
ENSG00000100201 E005 516.9438984 7.070343e-05 9.877590e-01 9.998311e-01 22 38485681 38486440 760 - 2.689 2.686 -0.008
ENSG00000100201 E006 6.6311381 9.880204e-03 9.569122e-02 3.221403e-01 22 38487873 38487878 6 - 0.975 0.789 -0.711
ENSG00000100201 E007 131.4791856 1.416532e-03 8.432911e-01 9.439784e-01 22 38487879 38488025 147 - 2.101 2.092 -0.028
ENSG00000100201 E008 113.6572512 1.748929e-04 2.738554e-01 5.676119e-01 22 38488026 38488115 90 - 2.056 2.021 -0.117
ENSG00000100201 E009 561.9221351 5.549304e-05 6.091984e-42 6.318559e-39 22 38488116 38489227 1112 - 2.589 2.777 0.624
ENSG00000100201 E010 124.1126889 2.294834e-03 7.017677e-07 3.394541e-05 22 38489228 38489458 231 - 1.943 2.121 0.598
ENSG00000100201 E011 280.7959193 7.375786e-05 1.678058e-19 4.351172e-17 22 38489459 38490312 854 - 2.295 2.474 0.596
ENSG00000100201 E012 64.4177335 2.552800e-04 5.718146e-05 1.487724e-03 22 38490313 38490436 124 - 1.671 1.837 0.561
ENSG00000100201 E013 437.2132390 5.160805e-05 3.963895e-26 1.781573e-23 22 38490437 38492055 1619 - 2.497 2.662 0.549
ENSG00000100201 E014 53.9833475 3.044428e-04 6.475079e-08 3.932736e-06 22 38492056 38492115 60 - 1.852 1.625 -0.768
ENSG00000100201 E015 2.7376152 6.169546e-03 4.673164e-01 7.357802e-01 22 38493361 38493709 349 - 0.481 0.585 0.489
ENSG00000100201 E016 61.1891544 2.910616e-04 9.264552e-10 7.969288e-08 22 38493710 38493771 62 - 1.914 1.672 -0.816
ENSG00000100201 E017 79.3120382 5.625337e-04 7.854699e-07 3.748985e-05 22 38494021 38494131 111 - 1.989 1.811 -0.598
ENSG00000100201 E018 1.5866865 8.561105e-03 1.618984e-01 4.301409e-01 22 38494310 38494629 320 - 0.527 0.315 -1.148
ENSG00000100201 E019 109.4213338 1.466951e-04 6.814718e-13 9.142910e-11 22 38494630 38494802 173 - 2.147 1.934 -0.715
ENSG00000100201 E020 115.0067233 1.939538e-03 1.299389e-05 4.270643e-04 22 38494886 38495046 161 - 2.132 1.982 -0.503
ENSG00000100201 E021 111.7965719 1.470956e-03 1.705074e-07 9.447452e-06 22 38495796 38495937 142 - 2.134 1.960 -0.584
ENSG00000100201 E022 87.2386433 3.667729e-04 7.566055e-09 5.499563e-07 22 38498085 38498150 66 - 2.040 1.845 -0.657
ENSG00000100201 E023 94.3705027 3.280956e-03 1.044741e-06 4.849142e-05 22 38498440 38498552 113 - 2.073 1.878 -0.654
ENSG00000100201 E024 44.0406931 1.114783e-02 9.336271e-03 7.690752e-02 22 38498553 38498573 21 - 1.732 1.565 -0.569
ENSG00000100201 E025 77.2468854 1.931352e-04 2.147717e-04 4.427943e-03 22 38499400 38499499 100 - 1.951 1.818 -0.447
ENSG00000100201 E026 77.5554956 2.002837e-04 2.155430e-03 2.700378e-02 22 38501130 38501280 151 - 1.940 1.829 -0.373
ENSG00000100201 E027 0.6167661 1.432539e-02 8.034821e-01 9.269322e-01 22 38505165 38505249 85 - 0.224 0.185 -0.341
ENSG00000100201 E028 1.1156873 3.510371e-02 9.392261e-01 9.826100e-01 22 38505462 38505950 489 - 0.304 0.315 0.074
ENSG00000100201 E029 86.8698506 8.915593e-04 2.624621e-08 1.728404e-06 22 38505951 38506337 387 - 2.039 1.842 -0.660
ENSG00000100201 E030 0.0000000       22 38507591 38507660 70 -      

Help

Please Click HERE to learn more details about the results from DEXseq.