ENSG00000100239

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359139 ENSG00000100239 No_inf pgKDN_inf PPP6R2 protein_coding protein_coding 35.00983 37.32432 30.1717 1.278786 1.612736 -0.3068281 1.948350 1.147174 2.394343 0.7390174 1.1182356 1.0550376 0.0570250 0.030825 0.081625 0.050800 0.79926617 0.04823454 FALSE TRUE
ENST00000470046 ENSG00000100239 No_inf pgKDN_inf PPP6R2 protein_coding retained_intron 35.00983 37.32432 30.1717 1.278786 1.612736 -0.3068281 6.653255 10.962191 3.481509 1.3934233 0.2714582 -1.6519292 0.1866167 0.294925 0.115875 -0.179050 0.04823454 0.04823454 FALSE FALSE
ENST00000473283 ENSG00000100239 No_inf pgKDN_inf PPP6R2 protein_coding retained_intron 35.00983 37.32432 30.1717 1.278786 1.612736 -0.3068281 4.571743 5.972804 2.154882 1.6699407 1.3999159 -1.4665332 0.1188667 0.156575 0.065325 -0.091250 0.47856743 0.04823454   FALSE
ENST00000612753 ENSG00000100239 No_inf pgKDN_inf PPP6R2 protein_coding protein_coding 35.00983 37.32432 30.1717 1.278786 1.612736 -0.3068281 7.826579 5.592346 8.251373 2.4029446 3.0040144 0.5603504 0.2316333 0.148625 0.281550 0.132925 0.80748950 0.04823454 FALSE TRUE
MSTRG.19653.2 ENSG00000100239 No_inf pgKDN_inf PPP6R2 protein_coding   35.00983 37.32432 30.1717 1.278786 1.612736 -0.3068281 2.692118 3.194361 2.718808 0.4481592 0.5075115 -0.2317660 0.0786250 0.085300 0.091300 0.006000 1.00000000 0.04823454 FALSE TRUE
MSTRG.19653.7 ENSG00000100239 No_inf pgKDN_inf PPP6R2 protein_coding   35.00983 37.32432 30.1717 1.278786 1.612736 -0.3068281 6.460647 6.033250 6.502654 2.2217631 3.3979827 0.1079210 0.1862917 0.165950 0.217900 0.051950 1.00000000 0.04823454 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100239 E001 0.4811992 0.0153461225 3.462568e-01   22 50343304 50343313 10 + 0.234 0.098 -1.501
ENSG00000100239 E002 1.3417587 0.0094350895 8.345031e-01 0.9403559135 22 50343314 50343322 9 + 0.385 0.354 -0.179
ENSG00000100239 E003 1.8396657 0.0077919751 7.192027e-01 0.8868074864 22 50343323 50343326 4 + 0.426 0.479 0.277
ENSG00000100239 E004 1.8396657 0.0077919751 7.192027e-01 0.8868074864 22 50343327 50343330 4 + 0.426 0.479 0.277
ENSG00000100239 E005 12.8101530 0.0015807260 3.282484e-01 0.6207486435 22 50343331 50343550 220 + 1.177 1.100 -0.275
ENSG00000100239 E006 8.7700877 0.0228104207 4.131902e-01 0.6940421013 22 50372020 50372071 52 + 1.031 0.945 -0.319
ENSG00000100239 E007 12.6556750 0.0361011452 3.519966e-01 0.6421086933 22 50372072 50372150 79 + 1.183 1.082 -0.362
ENSG00000100239 E008 5.0165935 0.0160650613 9.864410e-01 0.9993426421 22 50388986 50389111 126 + 0.778 0.781 0.014
ENSG00000100239 E009 1.0990613 0.0716882385 8.273290e-01 0.9374821804 22 50391867 50392015 149 + 0.340 0.303 -0.238
ENSG00000100239 E010 1.3196993 0.0933384217 6.084892e-02 0.2475951575 22 50393764 50393799 36 + 0.497 0.177 -2.086
ENSG00000100239 E011 31.5805324 0.0005706893 2.122026e-01 0.4974328566 22 50393893 50394135 243 + 1.544 1.481 -0.217
ENSG00000100239 E012 28.8222026 0.0008219479 5.349890e-01 0.7848678046 22 50406689 50406875 187 + 1.491 1.458 -0.112
ENSG00000100239 E013 18.6238634 0.0022200665 5.169553e-01 0.7725752281 22 50414552 50414689 138 + 1.269 1.315 0.160
ENSG00000100239 E014 9.7725169 0.0016366957 6.741757e-01 0.8649758801 22 50416092 50416157 66 + 1.050 1.014 -0.132
ENSG00000100239 E015 16.5231849 0.0009034516 9.502852e-01 0.9871661993 22 50418867 50418979 113 + 1.241 1.246 0.020
ENSG00000100239 E016 0.4886249 0.0158709095 9.567065e-01   22 50419346 50419348 3 + 0.169 0.177 0.084
ENSG00000100239 E017 18.0964607 0.0152898646 7.729103e-01 0.9125991562 22 50419349 50419441 93 + 1.291 1.271 -0.072
ENSG00000100239 E018 12.4286467 0.0174176382 2.465312e-01 0.5371549859 22 50419442 50419462 21 + 1.068 1.179 0.400
ENSG00000100239 E019 27.7201129 0.0006557248 4.735526e-01 0.7405644553 22 50422254 50422380 127 + 1.477 1.439 -0.132
ENSG00000100239 E020 33.4294548 0.0004575820 2.097466e-01 0.4942083596 22 50423462 50423604 143 + 1.567 1.505 -0.212
ENSG00000100239 E021 11.7032037 0.0133762156 3.913891e-01 0.6765670301 22 50423605 50423614 10 + 1.141 1.064 -0.279
ENSG00000100239 E022 0.5002991 0.0379930384 2.982726e-01 0.5912829229 22 50431070 50431172 103 + 0.093 0.245 1.669
ENSG00000100239 E023 36.5883054 0.0004592512 9.736694e-02 0.3250987908 22 50431173 50431382 210 + 1.532 1.614 0.278
ENSG00000100239 E024 16.6101583 0.0008800554 5.913803e-01 0.8193040656 22 50432265 50432329 65 + 1.264 1.227 -0.128
ENSG00000100239 E025 24.8046826 0.0005833139 1.494292e-02 0.1047752761 22 50434966 50435081 116 + 1.477 1.336 -0.489
ENSG00000100239 E026 22.4396811 0.0161820118 3.191551e-01 0.6118983902 22 50436367 50436452 86 + 1.406 1.331 -0.262
ENSG00000100239 E027 19.4646154 0.0007574314 9.124629e-01 0.9721809671 22 50436988 50437068 81 + 1.307 1.315 0.030
ENSG00000100239 E028 32.5445794 0.0075509419 1.445228e-01 0.4047298643 22 50437506 50437603 98 + 1.477 1.569 0.313
ENSG00000100239 E029 24.9471673 0.0139637721 1.770018e-01 0.4514018315 22 50437843 50437900 58 + 1.359 1.462 0.355
ENSG00000100239 E030 30.9934602 0.0005265642 6.129844e-01 0.8318103924 22 50438174 50438298 125 + 1.491 1.519 0.096
ENSG00000100239 E031 35.4537618 0.0004882703 7.211500e-01 0.8876706416 22 50438599 50438762 164 + 1.570 1.554 -0.055
ENSG00000100239 E032 1.9599081 0.0084346207 9.136354e-01 0.9727812249 22 50439698 50439700 3 + 0.463 0.479 0.084
ENSG00000100239 E033 18.9648605 0.0016636982 9.558310e-01 0.9893155486 22 50439701 50439752 52 + 1.301 1.299 -0.009
ENSG00000100239 E034 27.3017589 0.0004981716 1.072400e-01 0.3431609143 22 50439753 50439857 105 + 1.494 1.406 -0.304
ENSG00000100239 E035 1.6088114 0.3016505575 3.479583e-01 0.6384775881 22 50439858 50439960 103 + 0.290 0.514 1.255
ENSG00000100239 E036 23.1341826 0.0203274894 9.683810e-01 0.9936412263 22 50439961 50440049 89 + 1.377 1.388 0.038
ENSG00000100239 E037 1.2606676 0.1446058986 2.026062e-02 0.1280150276 22 50440332 50440462 131 + 0.093 0.514 3.254
ENSG00000100239 E038 1.4952032 0.0103735240 6.570931e-02 0.2582333319 22 50440801 50440821 21 + 0.234 0.514 1.669
ENSG00000100239 E039 31.5754741 0.0004934810 5.768562e-02 0.2403226059 22 50440822 50441026 205 + 1.460 1.560 0.343
ENSG00000100239 E040 2.4656905 0.0247475202 3.369354e-01 0.6288506355 22 50441027 50441074 48 + 0.463 0.605 0.670
ENSG00000100239 E041 6.9901169 0.0019815585 1.828786e-05 0.0005724536 22 50443087 50443865 779 + 0.612 1.073 1.810
ENSG00000100239 E042 0.0000000       22 50443866 50444117 252 +      
ENSG00000100239 E043 0.0000000       22 50444199 50444202 4 +      
ENSG00000100239 E044 0.0000000       22 50444203 50445090 888 +      

Help

Please Click HERE to learn more details about the results from DEXseq.