ENSG00000100284

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000411850 ENSG00000100284 No_inf pgKDN_inf TOM1 protein_coding protein_coding 30.23194 24.2333 32.70721 0.4152551 1.061755 0.4324637 8.460798 6.744228 8.017255 1.0487763 1.7836390 0.2491158 0.27903333 0.27695 0.241300 -0.035650 0.87787111 0.02996977 FALSE TRUE
ENST00000425375 ENSG00000100284 No_inf pgKDN_inf TOM1 protein_coding protein_coding 30.23194 24.2333 32.70721 0.4152551 1.061755 0.4324637 1.947567 0.000000 3.736553 0.0000000 3.7365526 8.5494199 0.05810833 0.00000 0.117425 0.117425 0.87552220 0.02996977 FALSE TRUE
ENST00000449058 ENSG00000100284 No_inf pgKDN_inf TOM1 protein_coding protein_coding 30.23194 24.2333 32.70721 0.4152551 1.061755 0.4324637 14.565448 11.151395 15.069176 0.9287704 2.7812388 0.4340403 0.48293333 0.46195 0.463425 0.001475 1.00000000 0.02996977 FALSE TRUE
ENST00000492723 ENSG00000100284 No_inf pgKDN_inf TOM1 protein_coding retained_intron 30.23194 24.2333 32.70721 0.4152551 1.061755 0.4324637 2.506118 3.838106 1.159151 0.2988424 0.2337492 -1.7186873 0.08915833 0.15800 0.036050 -0.121950 0.02996977 0.02996977 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100284 E001 0.0000000       22 35299275 35299375 101 +      
ENSG00000100284 E002 0.0000000       22 35299376 35299378 3 +      
ENSG00000100284 E003 0.0000000       22 35299379 35299494 116 +      
ENSG00000100284 E004 0.0000000       22 35299800 35299803 4 +      
ENSG00000100284 E005 0.0000000       22 35299804 35299855 52 +      
ENSG00000100284 E006 0.4984749 0.0195578811 2.549450e-01   22 35299856 35299865 10 + 0.089 0.253 1.795
ENSG00000100284 E007 0.4984749 0.0195578811 2.549450e-01   22 35299866 35299870 5 + 0.089 0.253 1.795
ENSG00000100284 E008 0.8705391 0.0137037277 1.839133e-01 4.609926e-01 22 35299871 35299873 3 + 0.163 0.365 1.532
ENSG00000100284 E009 2.0771429 0.0716383840 9.883519e-01 1.000000e+00 22 35299874 35299883 10 + 0.484 0.492 0.040
ENSG00000100284 E010 2.1947735 0.0391592834 8.650894e-01 9.533465e-01 22 35299884 35299889 6 + 0.515 0.492 -0.112
ENSG00000100284 E011 2.9023915 0.0079481218 2.040851e-01 4.867826e-01 22 35299890 35299893 4 + 0.667 0.492 -0.790
ENSG00000100284 E012 14.2571261 0.0010321742 5.537803e-01 7.968176e-01 22 35299894 35299980 87 + 1.205 1.159 -0.162
ENSG00000100284 E013 0.1186381 0.0118276263 6.234718e-01   22 35311062 35311127 66 + 0.089 0.000 -12.628
ENSG00000100284 E014 17.9842201 0.0008418102 1.127926e-01 3.533455e-01 22 35317877 35317961 85 + 1.327 1.218 -0.383
ENSG00000100284 E015 0.1186381 0.0118276263 6.234718e-01   22 35317962 35318316 355 + 0.089 0.000 -12.628
ENSG00000100284 E016 0.1271363 0.0123242643 4.634524e-01   22 35321742 35321847 106 + 0.000 0.101 12.075
ENSG00000100284 E017 15.6608798 0.0008790111 8.271966e-02 2.963599e-01 22 35321959 35322019 61 + 1.278 1.151 -0.450
ENSG00000100284 E018 9.8385445 0.0014223618 2.188109e-01 5.054977e-01 22 35322020 35322037 18 + 1.085 0.974 -0.404
ENSG00000100284 E019 0.4822342 0.0158022354 3.959622e-01   22 35322038 35322612 575 + 0.226 0.101 -1.375
ENSG00000100284 E020 0.1272623 0.0124255957 4.632704e-01   22 35322999 35323027 29 + 0.000 0.101 12.075
ENSG00000100284 E021 25.5941157 0.0005649734 3.787392e-01 6.656177e-01 22 35323028 35323177 150 + 1.448 1.397 -0.177
ENSG00000100284 E022 0.3528919 0.5488785153 3.481369e-01   22 35323340 35323495 156 + 0.226 0.000 -13.121
ENSG00000100284 E023 8.8020413 0.0017113852 8.770771e-01 9.582942e-01 22 35323496 35323518 23 + 0.984 0.998 0.050
ENSG00000100284 E024 19.3546518 0.0022724919 4.495494e-01 7.231783e-01 22 35323519 35323630 112 + 1.283 1.333 0.174
ENSG00000100284 E025 15.0264573 0.0009185291 9.928596e-01 1.000000e+00 22 35323768 35323867 100 + 1.205 1.204 -0.001
ENSG00000100284 E026 10.3136993 0.0013662733 1.082427e-01 3.450943e-01 22 35323868 35323914 47 + 1.116 0.974 -0.518
ENSG00000100284 E027 20.2797014 0.0007170259 9.815680e-01 9.982180e-01 22 35327271 35327387 117 + 1.327 1.328 0.001
ENSG00000100284 E028 23.6318036 0.0006911548 3.195932e-01 6.122674e-01 22 35330347 35330480 134 + 1.419 1.359 -0.209
ENSG00000100284 E029 0.1272623 0.0124255957 4.632704e-01   22 35331296 35331495 200 + 0.000 0.101 12.075
ENSG00000100284 E030 11.9713828 0.0403739157 5.574731e-02 2.352856e-01 22 35332981 35333014 34 + 1.205 0.986 -0.789
ENSG00000100284 E031 0.6166738 0.0225571252 5.428649e-01 7.899972e-01 22 35333175 35333403 229 + 0.163 0.253 0.795
ENSG00000100284 E032 18.5260407 0.0008632471 5.809719e-01 8.132919e-01 22 35333404 35333497 94 + 1.308 1.270 -0.133
ENSG00000100284 E033 20.2076044 0.0040741205 3.108545e-01 6.040127e-01 22 35334328 35334448 121 + 1.359 1.288 -0.245
ENSG00000100284 E034 16.3004248 0.0197398488 3.861738e-01 6.720628e-01 22 35338713 35338788 76 + 1.273 1.197 -0.268
ENSG00000100284 E035 19.9978370 0.0010741451 5.858399e-16 1.085797e-13 22 35344186 35345724 1539 + 0.963 1.527 1.995
ENSG00000100284 E036 14.7574597 0.0059123791 8.565714e-01 9.496088e-01 22 35345725 35345784 60 + 1.205 1.190 -0.053
ENSG00000100284 E037 15.1622170 0.0121527611 7.179331e-01 8.865073e-01 22 35346930 35346969 40 + 1.192 1.225 0.117
ENSG00000100284 E038 2.8377182 0.0050527839 1.660059e-01 4.360804e-01 22 35346970 35346972 3 + 0.484 0.671 0.848
ENSG00000100284 E039 124.1066401 0.0001545083 2.106395e-01 4.951893e-01 22 35347055 35347992 938 + 2.083 2.111 0.094

Help

Please Click HERE to learn more details about the results from DEXseq.