ENSG00000100297

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000216122 ENSG00000100297 No_inf pgKDN_inf MCM5 protein_coding protein_coding 36.80191 38.7464 38.1525 1.362487 2.697226 -0.02227909 27.1682040 26.208583 28.2056609 0.4722180 0.4971624 0.1059064 0.74763333 0.678075 0.754675 0.076600 0.78762889 0.0069689 FALSE TRUE
ENST00000416905 ENSG00000100297 No_inf pgKDN_inf MCM5 protein_coding protein_coding 36.80191 38.7464 38.1525 1.362487 2.697226 -0.02227909 0.7446842 2.234053 0.0000000 0.8563787 0.0000000 -7.8099627 0.01920833 0.057625 0.000000 -0.057625 0.04724171 0.0069689 FALSE FALSE
ENST00000464908 ENSG00000100297 No_inf pgKDN_inf MCM5 protein_coding protein_coding_CDS_not_defined 36.80191 38.7464 38.1525 1.362487 2.697226 -0.02227909 2.7162738 0.000000 6.7600834 0.0000000 2.3677931 9.4030298 0.06845833 0.000000 0.166825 0.166825 0.00696890 0.0069689 FALSE FALSE
MSTRG.19314.4 ENSG00000100297 No_inf pgKDN_inf MCM5 protein_coding   36.80191 38.7464 38.1525 1.362487 2.697226 -0.02227909 2.4311473 4.160773 0.6738116 0.4312665 0.2998103 -2.6086438 0.06654167 0.108125 0.016325 -0.091800 0.02154054 0.0069689 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100297 E001 0.2451451 0.0161918691 8.783560e-01   22 35400134 35400136 3 + 0.104 0.087 -0.284
ENSG00000100297 E002 0.2451451 0.0161918691 8.783560e-01   22 35400137 35400139 3 + 0.104 0.087 -0.284
ENSG00000100297 E003 0.4909846 0.0156733524 8.446501e-01   22 35400140 35400141 2 + 0.188 0.159 -0.284
ENSG00000100297 E004 4.5208831 0.0041968954 2.821958e-01 5.757716e-01 22 35400142 35400167 26 + 0.806 0.679 -0.518
ENSG00000100297 E005 5.2741353 0.0041364167 6.278913e-01 8.400317e-01 22 35400168 35400169 2 + 0.824 0.769 -0.217
ENSG00000100297 E006 10.8125904 0.0016729389 7.792254e-01 9.149984e-01 22 35400170 35400208 39 + 1.082 1.058 -0.087
ENSG00000100297 E007 16.3691725 0.0008629333 7.335169e-01 8.941058e-01 22 35400431 35400498 68 + 1.222 1.246 0.087
ENSG00000100297 E008 25.6128598 0.0010019464 2.268124e-01 5.150372e-01 22 35400499 35400605 107 + 1.460 1.389 -0.242
ENSG00000100297 E009 1.2591226 0.0118243592 1.699565e-02 1.138263e-01 22 35401371 35401466 96 + 0.104 0.477 2.886
ENSG00000100297 E010 0.5085150 0.0160629044 7.022405e-02 2.681266e-01 22 35401666 35401814 149 + 0.000 0.276 12.213
ENSG00000100297 E011 38.0052395 0.0005291218 1.993978e-01 4.810365e-01 22 35403207 35403333 127 + 1.621 1.560 -0.209
ENSG00000100297 E012 40.2952143 0.0077791279 7.061788e-01 8.806771e-01 22 35403414 35403517 104 + 1.624 1.603 -0.072
ENSG00000100297 E013 26.4769135 0.0007718909 5.005896e-01 7.605939e-01 22 35403518 35403542 25 + 1.412 1.452 0.135
ENSG00000100297 E014 56.7936184 0.0002732436 2.436190e-01 5.336341e-01 22 35406553 35406725 173 + 1.783 1.738 -0.153
ENSG00000100297 E015 40.5643637 0.0004878713 7.559975e-01 9.038400e-01 22 35408408 35408563 156 + 1.607 1.621 0.050
ENSG00000100297 E016 0.3730368 0.0165762592 7.123184e-01   22 35409478 35410008 531 + 0.104 0.159 0.716
ENSG00000100297 E017 0.4801918 0.0153151865 2.335197e-01   22 35410359 35410381 23 + 0.258 0.087 -1.869
ENSG00000100297 E018 1.5808627 0.0092666377 2.404817e-01 5.297196e-01 22 35410409 35410743 335 + 0.500 0.324 -0.962
ENSG00000100297 E019 43.2864490 0.0004144516 1.191503e-02 9.015503e-02 22 35410744 35410910 167 + 1.703 1.590 -0.381
ENSG00000100297 E020 0.1271363 0.0123074684 6.534214e-01   22 35411244 35411290 47 + 0.000 0.087 10.213
ENSG00000100297 E021 0.0000000       22 35411439 35411496 58 +      
ENSG00000100297 E022 49.1321065 0.0003058328 2.526767e-03 3.036512e-02 22 35412510 35412681 172 + 1.763 1.637 -0.427
ENSG00000100297 E023 32.4150440 0.0004925592 6.225522e-01 8.373705e-01 22 35413875 35413986 112 + 1.534 1.509 -0.087
ENSG00000100297 E024 33.2977720 0.0004090312 8.233985e-01 9.358757e-01 22 35415829 35415972 144 + 1.538 1.526 -0.038
ENSG00000100297 E025 24.6948413 0.0007213768 8.466774e-01 9.456191e-01 22 35416339 35416404 66 + 1.412 1.401 -0.039
ENSG00000100297 E026 58.1730986 0.0003016103 3.820586e-01 6.683119e-01 22 35416638 35416814 177 + 1.787 1.753 -0.113
ENSG00000100297 E027 42.5948007 0.0085732729 1.717065e-01 4.443344e-01 22 35417744 35417856 113 + 1.679 1.600 -0.267
ENSG00000100297 E028 54.6700585 0.0002909814 8.176595e-01 9.336156e-01 22 35419884 35420012 129 + 1.747 1.738 -0.030
ENSG00000100297 E029 51.6434806 0.0003527377 8.929104e-01 9.645020e-01 22 35421318 35421460 143 + 1.714 1.720 0.020
ENSG00000100297 E030 14.8478853 0.0010038136 3.193536e-06 1.272084e-04 22 35421461 35423213 1753 + 0.946 1.322 1.350
ENSG00000100297 E031 55.7978991 0.0002645152 1.690734e-01 4.407309e-01 22 35423214 35423341 128 + 1.719 1.773 0.185
ENSG00000100297 E032 20.6567446 0.0007050466 4.407956e-12 5.294849e-10 22 35423342 35424153 812 + 0.984 1.484 1.772
ENSG00000100297 E033 100.3492134 0.0004397527 9.064048e-03 7.544141e-02 22 35424154 35425431 1278 + 1.956 2.034 0.262

Help

Please Click HERE to learn more details about the results from DEXseq.