ENSG00000100345

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000216181 ENSG00000100345 No_inf pgKDN_inf MYH9 protein_coding protein_coding 296.6955 212.6534 329.479 1.876811 2.64483 0.6316586 204.61126 120.0591 251.0948 0.3405535 2.190170 1.0644248 0.6748417 0.564750 0.762150 0.1974 8.967590e-17 8.96759e-17 FALSE TRUE
ENST00000690244 ENSG00000100345 No_inf pgKDN_inf MYH9 protein_coding retained_intron 296.6955 212.6534 329.479 1.876811 2.64483 0.6316586 82.11571 79.7513 72.8188 2.4108701 2.668099 -0.1311798 0.2883917 0.374825 0.220925 -0.1539 1.002923e-06 8.96759e-17 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100345 E001 11.7594795 2.733293e-02 7.982093e-02 2.899875e-01 22 36281280 36281291 12 - 1.014 1.199 0.666
ENSG00000100345 E002 16.2527666 5.053823e-03 5.670448e-02 2.376855e-01 22 36281292 36281296 5 - 1.162 1.312 0.531
ENSG00000100345 E003 2443.9395287 8.830005e-05 2.539146e-45 3.184798e-42 22 36281297 36282785 1489 - 3.339 3.432 0.310
ENSG00000100345 E004 266.4612386 1.685178e-03 1.037074e-01 3.365485e-01 22 36284093 36284161 69 - 2.399 2.444 0.150
ENSG00000100345 E005 228.6880104 1.866837e-04 1.353544e-01 3.910129e-01 22 36284162 36284213 52 - 2.337 2.372 0.116
ENSG00000100345 E006 259.3948557 8.284175e-05 7.955877e-01 9.223427e-01 22 36284214 36284265 52 - 2.402 2.411 0.028
ENSG00000100345 E007 1.2341691 9.941306e-03 1.622612e-01 4.306808e-01 22 36284266 36284307 42 - 0.246 0.461 1.311
ENSG00000100345 E008 1.2047380 2.232684e-01 6.197946e-01 8.354912e-01 22 36284308 36284402 95 - 0.368 0.289 -0.495
ENSG00000100345 E009 359.8050335 9.728713e-04 7.500262e-01 9.014575e-01 22 36284403 36284511 109 - 2.543 2.554 0.034
ENSG00000100345 E010 437.0376361 1.017300e-04 1.061381e-03 1.568773e-02 22 36285121 36285329 209 - 2.610 2.663 0.176
ENSG00000100345 E011 285.6181656 8.715268e-05 9.982036e-02 3.300865e-01 22 36285658 36285781 124 - 2.434 2.468 0.113
ENSG00000100345 E012 260.9031918 9.081073e-05 3.676133e-01 6.562576e-01 22 36285865 36285953 89 - 2.414 2.400 -0.047
ENSG00000100345 E013 1.0990342 1.828486e-02 6.920531e-01 8.739421e-01 22 36285954 36286044 91 - 0.290 0.354 0.404
ENSG00000100345 E014 5.2907154 2.874464e-03 1.893631e-02 1.225180e-01 22 36286155 36286717 563 - 0.664 0.932 1.063
ENSG00000100345 E015 349.3554146 6.649625e-05 9.917445e-01 1.000000e+00 22 36286718 36286846 129 - 2.533 2.537 0.012
ENSG00000100345 E016 9.0069561 1.671745e-03 1.620539e-12 2.042106e-10 22 36286847 36288211 1365 - 0.586 1.277 2.652
ENSG00000100345 E017 433.3874536 2.541997e-04 9.350153e-02 3.179641e-01 22 36288252 36288413 162 - 2.637 2.613 -0.079
ENSG00000100345 E018 409.1798725 5.800080e-05 1.612093e-01 4.293585e-01 22 36288727 36288939 213 - 2.610 2.592 -0.061
ENSG00000100345 E019 307.5677797 7.541796e-05 2.035015e-01 4.860999e-01 22 36289085 36289297 213 - 2.487 2.468 -0.064
ENSG00000100345 E020 395.5499283 5.680320e-05 1.412658e-03 1.954098e-02 22 36291986 36292234 249 - 2.606 2.559 -0.157
ENSG00000100345 E021 236.0226172 7.810892e-05 3.812858e-01 6.677470e-01 22 36293329 36293481 153 - 2.370 2.356 -0.048
ENSG00000100345 E022 158.0098347 3.382036e-04 4.309770e-01 7.087184e-01 22 36293759 36293863 105 - 2.198 2.181 -0.056
ENSG00000100345 E023 290.0442944 7.296926e-05 1.569724e-01 4.233286e-01 22 36294092 36294298 207 - 2.463 2.440 -0.075
ENSG00000100345 E024 196.0798508 9.196089e-05 6.510183e-01 8.530243e-01 22 36294932 36295076 145 - 2.287 2.281 -0.022
ENSG00000100345 E025 77.4628296 5.457016e-04 1.617414e-01 4.300440e-01 22 36295505 36295511 7 - 1.863 1.917 0.181
ENSG00000100345 E026 269.1710007 7.364289e-05 3.402189e-01 6.318994e-01 22 36295512 36295717 206 - 2.413 2.435 0.072
ENSG00000100345 E027 231.2060229 8.173206e-05 4.064778e-01 6.891374e-01 22 36296843 36297014 172 - 2.361 2.348 -0.046
ENSG00000100345 E028 0.8711996 1.323205e-02 7.511757e-02 2.797149e-01 22 36297015 36297323 309 - 0.140 0.411 2.048
ENSG00000100345 E029 195.7577924 1.079590e-04 2.886002e-02 1.592201e-01 22 36298919 36299042 124 - 2.302 2.256 -0.154
ENSG00000100345 E030 189.4257395 1.960168e-04 7.555772e-02 2.807917e-01 22 36300127 36300264 138 - 2.284 2.246 -0.127
ENSG00000100345 E031 105.0898289 1.407824e-04 2.572601e-01 5.495293e-01 22 36300851 36300909 59 - 2.028 1.997 -0.105
ENSG00000100345 E032 155.8676809 1.008892e-04 2.992223e-03 3.447415e-02 22 36300910 36301057 148 - 2.213 2.141 -0.240
ENSG00000100345 E033 130.9342624 2.602479e-04 5.463663e-06 2.029457e-04 22 36301534 36301665 132 - 2.156 2.030 -0.422
ENSG00000100345 E034 0.2447669 1.657362e-02 7.002185e-01   22 36301666 36301714 49 - 0.076 0.119 0.726
ENSG00000100345 E035 1.1169441 4.046065e-02 9.471677e-02 3.202244e-01 22 36302308 36302567 260 - 0.196 0.461 1.726
ENSG00000100345 E036 110.0894461 1.422830e-04 3.657185e-03 3.991801e-02 22 36302568 36302676 109 - 2.067 1.983 -0.283
ENSG00000100345 E037 177.2330304 7.563532e-04 2.180662e-03 2.723757e-02 22 36303995 36304155 161 - 2.270 2.193 -0.258
ENSG00000100345 E038 124.4922138 3.720973e-04 9.395119e-03 7.716101e-02 22 36305033 36305102 70 - 2.116 2.044 -0.242
ENSG00000100345 E039 0.9639653 1.046636e-01 4.795294e-01 7.452667e-01 22 36305723 36305929 207 - 0.331 0.212 -0.860
ENSG00000100345 E040 135.6528685 1.215865e-04 2.902525e-04 5.655520e-03 22 36305930 36306051 122 - 2.161 2.065 -0.320
ENSG00000100345 E041 200.8750216 9.197539e-05 2.119624e-05 6.462397e-04 22 36306414 36306607 194 - 2.329 2.237 -0.308
ENSG00000100345 E042 0.1272623 1.238176e-02 3.204414e-01   22 36308695 36308807 113 - 0.000 0.119 12.072
ENSG00000100345 E043 0.3717469 1.671310e-02 3.224616e-01   22 36308808 36308870 63 - 0.076 0.212 1.726
ENSG00000100345 E044 0.8632958 1.614790e-02 3.088367e-01 6.021981e-01 22 36308871 36309281 411 - 0.196 0.354 1.141
ENSG00000100345 E045 137.2324762 1.694617e-04 4.547320e-02 2.085681e-01 22 36309282 36309396 115 - 2.150 2.099 -0.170
ENSG00000100345 E046 0.6096878 2.286658e-02 9.229269e-01 9.763295e-01 22 36309397 36309460 64 - 0.196 0.212 0.141
ENSG00000100345 E047 1.5130206 8.506854e-03 1.047032e-04 2.463815e-03 22 36310906 36311579 674 - 0.076 0.650 4.186
ENSG00000100345 E048 0.8890123 1.209869e-02 5.606813e-04 9.557454e-03 22 36311580 36312048 469 - 0.000 0.506 14.868
ENSG00000100345 E049 154.5343492 1.465458e-04 4.120395e-01 6.935329e-01 22 36312049 36312222 174 - 2.189 2.171 -0.058
ENSG00000100345 E050 128.9699527 2.646843e-03 4.274470e-01 7.060062e-01 22 36314145 36314318 174 - 2.113 2.089 -0.081
ENSG00000100345 E051 0.0000000       22 36316513 36316516 4 -      
ENSG00000100345 E052 135.9555317 3.456069e-04 1.928193e-02 1.240992e-01 22 36316517 36316669 153 - 2.150 2.088 -0.207
ENSG00000100345 E053 0.9790750 1.212737e-02 4.908375e-01 7.533379e-01 22 36317299 36318206 908 - 0.246 0.354 0.726
ENSG00000100345 E054 116.6955968 3.357124e-04 3.975905e-03 4.225195e-02 22 36318207 36318325 119 - 2.092 2.009 -0.278
ENSG00000100345 E055 103.9796531 3.580624e-04 7.595813e-01 9.056297e-01 22 36319540 36319635 96 - 2.014 2.007 -0.021
ENSG00000100345 E056 1.7268554 8.168854e-02 1.956077e-01 4.759016e-01 22 36319636 36320219 584 - 0.331 0.546 1.141
ENSG00000100345 E057 49.4810896 5.136901e-03 6.484458e-01 8.515736e-01 22 36320220 36320240 21 - 1.701 1.680 -0.071
ENSG00000100345 E058 60.3188930 3.824924e-03 2.590651e-01 5.516092e-01 22 36320241 36320273 33 - 1.797 1.746 -0.171
ENSG00000100345 E059 95.7624471 7.593893e-04 6.832531e-03 6.205890e-02 22 36320274 36320363 90 - 2.009 1.920 -0.298
ENSG00000100345 E060 1.1242762 1.254231e-02 1.597152e-02 1.096357e-01 22 36320364 36320797 434 - 0.140 0.506 2.534
ENSG00000100345 E061 92.3513769 1.688458e-04 3.801853e-02 1.880760e-01 22 36320798 36320896 99 - 1.985 1.920 -0.217
ENSG00000100345 E062 2.6011644 9.547306e-03 9.156980e-03 7.586345e-02 22 36320957 36321757 801 - 0.368 0.733 1.726
ENSG00000100345 E063 73.1015127 5.846125e-04 1.809020e-03 2.364132e-02 22 36321758 36321821 64 - 1.902 1.786 -0.390
ENSG00000100345 E064 0.1187032 1.185576e-02 9.602302e-01   22 36321822 36321922 101 - 0.076 0.000 -12.032
ENSG00000100345 E065 88.7721545 7.560667e-04 5.791385e-03 5.502071e-02 22 36322429 36322521 93 - 1.978 1.884 -0.315
ENSG00000100345 E066 0.4917399 1.591100e-02 6.242617e-01   22 36322522 36322994 473 - 0.140 0.212 0.726
ENSG00000100345 E067 1.2251667 1.008326e-02 4.415347e-01 7.170003e-01 22 36324287 36324668 382 - 0.290 0.411 0.726
ENSG00000100345 E068 0.1187032 1.185576e-02 9.602302e-01   22 36325033 36325071 39 - 0.076 0.000 -12.032
ENSG00000100345 E069 0.0000000       22 36325072 36325123 52 -      
ENSG00000100345 E070 0.9728782 5.977736e-02 9.846631e-01 9.989245e-01 22 36325124 36326035 912 - 0.290 0.289 -0.011
ENSG00000100345 E071 81.7906667 2.015061e-04 1.436388e-02 1.020284e-01 22 36326568 36326661 94 - 1.939 1.856 -0.277
ENSG00000100345 E072 54.4855895 2.759114e-04 6.990072e-03 6.299878e-02 22 36327461 36327488 28 - 1.775 1.663 -0.381
ENSG00000100345 E073 0.1265070 1.231076e-02 3.204214e-01   22 36328859 36328952 94 - 0.000 0.119 12.074
ENSG00000100345 E074 111.6391844 1.496724e-04 4.191695e-02 1.992025e-01 22 36341370 36341526 157 - 2.064 2.006 -0.192
ENSG00000100345 E075 45.0779693 7.582066e-03 9.036271e-02 3.121636e-01 22 36348904 36348927 24 - 1.690 1.592 -0.332
ENSG00000100345 E076 174.9268007 1.281778e-04 3.239597e-07 1.681660e-05 22 36348928 36349255 328 - 2.279 2.158 -0.404
ENSG00000100345 E077 0.2346346 1.565360e-02 4.649886e-01   22 36364779 36364833 55 - 0.140 0.000 -12.920
ENSG00000100345 E078 0.0000000       22 36365046 36365112 67 -      
ENSG00000100345 E079 0.1271363 1.236416e-02 3.204491e-01   22 36370586 36370610 25 - 0.000 0.119 12.072
ENSG00000100345 E080 63.2396814 1.915496e-03 1.969344e-01 4.779921e-01 22 36387807 36388010 204 - 1.818 1.766 -0.175

Help

Please Click HERE to learn more details about the results from DEXseq.