ENSG00000100360

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415653 ENSG00000100360 No_inf pgKDN_inf IFT27 protein_coding nonsense_mediated_decay 22.41079 26.99523 22.35147 1.243937 1.704678 -0.2722234 0.4476595 0.000000 1.3429785 0.0000000 0.4778193 7.0799951 0.01972500 0.000000 0.059175 0.059175 0.04310154 0.04310154 TRUE  
ENST00000433985 ENSG00000100360 No_inf pgKDN_inf IFT27 protein_coding protein_coding 22.41079 26.99523 22.35147 1.243937 1.704678 -0.2722234 15.2618327 14.899276 16.3760907 1.9733041 0.8648404 0.1362615 0.70497500 0.561775 0.737500 0.175725 0.48139014 0.04310154 FALSE  
ENST00000471809 ENSG00000100360 No_inf pgKDN_inf IFT27 protein_coding retained_intron 22.41079 26.99523 22.35147 1.243937 1.704678 -0.2722234 1.6587276 2.912459 1.0513341 0.3757222 0.1475317 -1.4613040 0.07116667 0.109900 0.046900 -0.063000 0.45893663 0.04310154 FALSE  
ENST00000495555 ENSG00000100360 No_inf pgKDN_inf IFT27 protein_coding retained_intron 22.41079 26.99523 22.35147 1.243937 1.704678 -0.2722234 1.0376406 2.198700 0.4969587 1.1534110 0.4969587 -2.1232573 0.04343333 0.084875 0.024800 -0.060075 0.56059243 0.04310154 FALSE  
ENST00000495987 ENSG00000100360 No_inf pgKDN_inf IFT27 protein_coding protein_coding_CDS_not_defined 22.41079 26.99523 22.35147 1.243937 1.704678 -0.2722234 1.4316044 3.168317 1.1264959 3.1683173 1.1264959 -1.4836708 0.04877500 0.103600 0.042725 -0.060875 1.00000000 0.04310154 FALSE  
MSTRG.19341.8 ENSG00000100360 No_inf pgKDN_inf IFT27 protein_coding   22.41079 26.99523 22.35147 1.243937 1.704678 -0.2722234 1.4965212 2.828095 0.3249872 0.5194194 0.1895845 -3.0827454 0.06540000 0.103550 0.016675 -0.086875 0.07918607 0.04310154 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100360 E001 0.1187032 0.0118072790 2.483927e-01   22 36758202 36758210 9 - 0.130 0.000 -10.250
ENSG00000100360 E002 0.1187032 0.0118072790 2.483927e-01   22 36758211 36758216 6 - 0.130 0.000 -12.583
ENSG00000100360 E003 0.8627014 0.0145476419 5.846249e-01 8.153960e-01 22 36758217 36758224 8 - 0.311 0.227 -0.609
ENSG00000100360 E004 20.7194407 0.0009896690 3.372338e-02 1.747537e-01 22 36758225 36758409 185 - 1.393 1.259 -0.467
ENSG00000100360 E005 57.4700785 0.0002881133 8.718102e-19 2.108530e-16 22 36758410 36760745 2336 - 1.434 1.824 1.329
ENSG00000100360 E006 3.1348620 0.0101069443 6.099540e-02 2.479271e-01 22 36760746 36760843 98 - 0.379 0.663 1.368
ENSG00000100360 E007 3.2452166 0.0329005276 3.238995e-01 6.164978e-01 22 36760844 36760919 76 - 0.491 0.647 0.713
ENSG00000100360 E008 33.7983479 0.0101425143 3.576842e-05 1.002068e-03 22 36760920 36762903 1984 - 1.298 1.581 0.976
ENSG00000100360 E009 9.2617516 0.0015593012 2.884483e-01 5.820096e-01 22 36762904 36762932 29 - 1.046 0.949 -0.358
ENSG00000100360 E010 19.1990313 0.0045512763 7.354542e-01 8.951119e-01 22 36762933 36763013 81 - 1.290 1.267 -0.079
ENSG00000100360 E011 11.6158899 0.0012839363 2.738614e-02 1.540738e-01 22 36763014 36763918 905 - 0.921 1.126 0.754
ENSG00000100360 E012 19.2996422 0.0008742495 1.715383e-03 2.267030e-02 22 36763919 36763995 77 - 1.405 1.202 -0.710
ENSG00000100360 E013 11.6873204 0.0131116752 1.080683e-05 3.658853e-04 22 36763996 36764036 41 - 1.305 0.905 -1.447
ENSG00000100360 E014 8.4111092 0.0191951891 8.622770e-04 1.337919e-02 22 36766138 36766197 60 - 1.154 0.801 -1.317
ENSG00000100360 E015 1.1244610 0.2022487128 5.701659e-01 8.068837e-01 22 36766198 36766467 270 - 0.230 0.343 0.784
ENSG00000100360 E016 0.0000000       22 36767063 36767305 243 -      
ENSG00000100360 E017 0.0000000       22 36767306 36767365 60 -      
ENSG00000100360 E018 0.0000000       22 36767783 36767859 77 -      
ENSG00000100360 E019 0.0000000       22 36767860 36767862 3 -      
ENSG00000100360 E020 0.0000000       22 36767983 36768099 117 -      
ENSG00000100360 E021 0.0000000       22 36768100 36768554 455 -      
ENSG00000100360 E022 0.9812160 0.0131042945 3.230458e-01 6.158114e-01 22 36772403 36772721 319 - 0.380 0.227 -1.024
ENSG00000100360 E023 12.1783235 0.0048771919 3.169402e-02 1.681804e-01 22 36775674 36775794 121 - 1.204 1.026 -0.643
ENSG00000100360 E024 27.9077892 0.0006295145 2.344303e-04 4.765836e-03 22 36775795 36776030 236 - 1.555 1.358 -0.679
ENSG00000100360 E025 9.6859225 0.0014995100 4.774939e-03 4.794854e-02 22 36776031 36776256 226 - 1.154 0.905 -0.914

Help

Please Click HERE to learn more details about the results from DEXseq.