ENSG00000100365

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000248899 ENSG00000100365 No_inf pgKDN_inf NCF4 protein_coding protein_coding 117.6791 143.9401 102.5405 1.124262 2.002378 -0.4892344 75.31975 83.60608 73.870234 3.6338864 3.536735 -0.1785921 0.6473250 0.580500 0.719475 0.138975 0.02705397 0.02705397 FALSE TRUE
ENST00000397147 ENSG00000100365 No_inf pgKDN_inf NCF4 protein_coding protein_coding 117.6791 143.9401 102.5405 1.124262 2.002378 -0.4892344 26.93080 32.00338 21.994551 2.8065609 4.947210 -0.5408733 0.2312833 0.222675 0.216975 -0.005700 0.95239577 0.02705397 FALSE TRUE
ENST00000415063 ENSG00000100365 No_inf pgKDN_inf NCF4 protein_coding protein_coding_CDS_not_defined 117.6791 143.9401 102.5405 1.124262 2.002378 -0.4892344 13.59570 24.31076 6.240977 0.9449657 3.624207 -1.9600344 0.1073750 0.168850 0.059175 -0.109675 0.31069638 0.02705397 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100365 E001 1.2601616 0.1605776835 0.0847033701 0.300710345 22 36860988 36861005 18 + 0.115 0.443 2.539
ENSG00000100365 E002 81.8318037 0.0001886454 0.1611167596 0.429255462 22 36861006 36861203 198 + 1.930 1.888 -0.139
ENSG00000100365 E003 0.3809703 0.0244831110 0.2249165091   22 36862303 36862387 85 + 0.000 0.201 10.305
ENSG00000100365 E004 2.1335011 0.0069495730 0.0593040937 0.244338600 22 36862524 36862781 258 + 0.282 0.575 1.592
ENSG00000100365 E005 0.6263978 0.0141400531 0.3771032624 0.664171084 22 36863091 36863146 56 + 0.115 0.252 1.370
ENSG00000100365 E006 1.1431900 0.0113255334 0.0069385062 0.062721077 22 36863147 36863225 79 + 0.000 0.443 11.890
ENSG00000100365 E007 69.5148226 0.0002186083 0.2128565248 0.498023009 22 36864045 36864129 85 + 1.859 1.819 -0.134
ENSG00000100365 E008 103.2274943 0.0009461370 0.0930604708 0.316943716 22 36864919 36865072 154 + 2.033 1.986 -0.158
ENSG00000100365 E009 32.4919968 0.0019122815 0.2217582987 0.508979074 22 36867392 36867462 71 + 1.549 1.487 -0.212
ENSG00000100365 E010 52.0249360 0.0003212604 0.3915185126 0.676636639 22 36870415 36870542 128 + 1.730 1.699 -0.105
ENSG00000100365 E011 64.4994094 0.0002219008 0.4568475386 0.728992733 22 36871652 36871709 58 + 1.817 1.794 -0.077
ENSG00000100365 E012 1.2517579 0.0161204657 0.2045877104 0.487571631 22 36872137 36872254 118 + 0.207 0.411 1.370
ENSG00000100365 E013 88.3906524 0.0054904181 0.4350740395 0.711975340 22 36872327 36872425 99 + 1.955 1.926 -0.097
ENSG00000100365 E014 133.9296258 0.0001825882 0.3372438650 0.629079875 22 36875653 36875783 131 + 2.128 2.109 -0.065
ENSG00000100365 E015 16.0085746 0.0198385215 0.2328999776 0.521567964 22 36875784 36875787 4 + 1.140 1.258 0.420
ENSG00000100365 E016 73.8072835 0.0030419064 0.0001127863 0.002620991 22 36875788 36876028 241 + 1.747 1.916 0.571
ENSG00000100365 E017 94.9071366 0.0001896163 0.4297282448 0.707866445 22 36876029 36876094 66 + 1.949 1.979 0.099
ENSG00000100365 E018 239.6000725 0.0035023372 0.3440026034 0.635369899 22 36877628 36878017 390 + 2.348 2.379 0.101

Help

Please Click HERE to learn more details about the results from DEXseq.