ENSG00000100368

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000403662 ENSG00000100368 No_inf pgKDN_inf CSF2RB protein_coding protein_coding 17.84482 14.61557 19.30458 0.4027127 0.4898726 0.4011969 2.7381085 1.0267704 5.2127072 1.0267704 3.0142312 2.3327014 0.14764167 0.066750 0.273950 0.207200 0.8157534 0.0216254 FALSE TRUE
ENST00000406230 ENSG00000100368 No_inf pgKDN_inf CSF2RB protein_coding protein_coding 17.84482 14.61557 19.30458 0.4027127 0.4898726 0.4011969 1.4641084 1.0489099 1.6994776 1.0489099 1.1505963 0.6909757 0.08154167 0.077625 0.085425 0.007800 0.8353706 0.0216254 FALSE TRUE
MSTRG.19345.1 ENSG00000100368 No_inf pgKDN_inf CSF2RB protein_coding   17.84482 14.61557 19.30458 0.4027127 0.4898726 0.4011969 1.1521166 0.8870132 0.2760651 0.5905614 0.2760651 -1.6487858 0.06384167 0.062275 0.013550 -0.048725 0.8039302 0.0216254 FALSE TRUE
MSTRG.19345.3 ENSG00000100368 No_inf pgKDN_inf CSF2RB protein_coding   17.84482 14.61557 19.30458 0.4027127 0.4898726 0.4011969 0.7246586 0.1717415 1.4071673 0.1717415 0.6135305 2.9630500 0.03780833 0.011175 0.071950 0.060775 0.4799314 0.0216254 FALSE TRUE
MSTRG.19345.4 ENSG00000100368 No_inf pgKDN_inf CSF2RB protein_coding   17.84482 14.61557 19.30458 0.4027127 0.4898726 0.4011969 8.4057610 5.4112708 9.2419509 1.5904554 1.5418670 0.7711265 0.46085000 0.365500 0.477025 0.111525 0.8196670 0.0216254 FALSE TRUE
MSTRG.19345.6 ENSG00000100368 No_inf pgKDN_inf CSF2RB protein_coding   17.84482 14.61557 19.30458 0.4027127 0.4898726 0.4011969 3.3600661 6.0698676 1.4672093 0.2059738 1.4672093 -2.0411657 0.20830833 0.416700 0.078075 -0.338625 0.0216254 0.0216254 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100368 E001 0.2454921 0.016419278 0.88830399   22 36913610 36913627 18 + 0.088 0.103 0.258
ENSG00000100368 E002 0.3723461 0.216276411 0.52853318   22 36913628 36913641 14 + 0.088 0.186 1.260
ENSG00000100368 E003 0.8540187 0.015294315 0.89080796 0.96365730 22 36913642 36913644 3 + 0.277 0.256 -0.154
ENSG00000100368 E004 1.4705675 0.059131512 0.77833352 0.91486644 22 36913645 36913677 33 + 0.370 0.416 0.260
ENSG00000100368 E005 4.7436031 0.003125223 0.57640066 0.81048908 22 36922036 36922133 98 + 0.788 0.723 -0.263
ENSG00000100368 E006 6.3367376 0.002542370 0.85386536 0.94841886 22 36922134 36922283 150 + 0.874 0.855 -0.074
ENSG00000100368 E007 0.0000000       22 36922612 36922730 119 +      
ENSG00000100368 E008 6.6370467 0.002724714 0.02859976 0.15838379 22 36923244 36923367 124 + 0.978 0.745 -0.900
ENSG00000100368 E009 8.0658840 0.001824464 0.81260058 0.93111814 22 36925987 36926177 191 + 0.946 0.969 0.086
ENSG00000100368 E010 7.7421582 0.003011275 0.04155025 0.19815821 22 36929402 36929559 158 + 1.026 0.821 -0.773
ENSG00000100368 E011 7.3512029 0.003368189 0.01169002 0.08905216 22 36929639 36929807 169 + 1.026 0.765 -0.996
ENSG00000100368 E012 10.5902074 0.001322540 0.43920730 0.71516589 22 36930375 36930510 136 + 1.094 1.027 -0.242
ENSG00000100368 E013 0.9903372 0.072475994 0.36462479 0.65319274 22 36930655 36930672 18 + 0.223 0.369 0.998
ENSG00000100368 E014 14.7152266 0.001190228 0.17659796 0.45086945 22 36930673 36930830 158 + 1.145 1.246 0.357
ENSG00000100368 E015 15.5197557 0.002548353 0.82925103 0.93823163 22 36932765 36932904 140 + 1.210 1.225 0.056
ENSG00000100368 E016 13.1675831 0.003052420 0.68771074 0.87125553 22 36933832 36933994 163 + 1.166 1.133 -0.116
ENSG00000100368 E017 0.4906064 0.075128468 0.86874592   22 36935315 36935350 36 + 0.161 0.186 0.261
ENSG00000100368 E018 7.4535200 0.002598249 0.94827402 0.98654009 22 36935351 36935441 91 + 0.923 0.929 0.024
ENSG00000100368 E019 5.8710443 0.018160966 0.77124207 0.91184122 22 36935630 36935687 58 + 0.819 0.855 0.140
ENSG00000100368 E020 7.5079202 0.001907934 0.06417858 0.25509769 22 36936549 36936652 104 + 1.007 0.821 -0.705
ENSG00000100368 E021 324.9750267 0.000109722 0.04007350 0.19403769 22 36937377 36940482 3106 + 2.504 2.522 0.061

Help

Please Click HERE to learn more details about the results from DEXseq.