ENSG00000100567

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000216455 ENSG00000100567 No_inf pgKDN_inf PSMA3 protein_coding protein_coding 75.17696 73.6787 75.67686 2.353124 3.932195 0.03859945 32.380497 23.812101 42.167716 1.8336392 1.5270961 0.8241803 0.43646667 0.323700 0.563050 0.239350 0.006395027 0.006395027 FALSE TRUE
ENST00000555743 ENSG00000100567 No_inf pgKDN_inf PSMA3 protein_coding retained_intron 75.17696 73.6787 75.67686 2.353124 3.932195 0.03859945 8.634194 9.912002 4.956444 3.4555263 2.8955349 -0.9984180 0.11534167 0.139100 0.060625 -0.078475 0.818526315 0.006395027 FALSE TRUE
ENST00000557087 ENSG00000100567 No_inf pgKDN_inf PSMA3 protein_coding nonsense_mediated_decay 75.17696 73.6787 75.67686 2.353124 3.932195 0.03859945 16.751706 17.337814 13.087364 3.6063271 3.4556065 -0.4054774 0.21465833 0.232550 0.167700 -0.064850 0.787716002 0.006395027 FALSE FALSE
ENST00000557290 ENSG00000100567 No_inf pgKDN_inf PSMA3 protein_coding retained_intron 75.17696 73.6787 75.67686 2.353124 3.932195 0.03859945 7.329074 9.598985 5.739524 0.7479315 0.7215771 -0.7409416 0.09755000 0.130000 0.075050 -0.054950 0.388361738 0.006395027   FALSE
MSTRG.8587.2 ENSG00000100567 No_inf pgKDN_inf PSMA3 protein_coding   75.17696 73.6787 75.67686 2.353124 3.932195 0.03859945 5.775906 7.092691 5.132534 1.1648893 0.5717204 -0.4658861 0.07881667 0.097775 0.069575 -0.028200 0.822583219 0.006395027 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100567 E001 1.3521457 0.0096715676 7.837177e-01 9.167836e-01 14 58244786 58244842 57 + 0.348 0.391 0.250
ENSG00000100567 E002 1.3521457 0.0096715676 7.837177e-01 9.167836e-01 14 58244843 58244845 3 + 0.348 0.391 0.250
ENSG00000100567 E003 3.1507690 0.0058907014 1.113964e-01 3.505146e-01 14 58244846 58244855 10 + 0.714 0.504 -0.931
ENSG00000100567 E004 5.0463008 0.0257529937 5.243929e-01 7.775379e-01 14 58244856 58244865 10 + 0.734 0.820 0.341
ENSG00000100567 E005 8.4709229 0.0016797814 5.898035e-01 8.183488e-01 14 58244866 58244872 7 + 0.948 1.001 0.196
ENSG00000100567 E006 8.7242839 0.0015822957 4.435600e-01 7.183427e-01 14 58244873 58244873 1 + 0.948 1.021 0.272
ENSG00000100567 E007 9.8413225 0.0014254588 2.942585e-01 5.875887e-01 14 58244874 58244876 3 + 0.983 1.078 0.350
ENSG00000100567 E008 12.0676870 0.0071180383 2.127329e-01 4.979401e-01 14 58244877 58244878 2 + 1.054 1.166 0.402
ENSG00000100567 E009 18.5568172 0.0007503339 3.314689e-01 6.236400e-01 14 58244879 58244903 25 + 1.254 1.322 0.236
ENSG00000100567 E010 27.2041254 0.0005205862 9.745392e-01 9.954114e-01 14 58244904 58244941 38 + 1.448 1.452 0.013
ENSG00000100567 E011 0.0000000       14 58245112 58245478 367 +      
ENSG00000100567 E012 31.5902939 0.0075550768 9.018417e-02 3.119895e-01 14 58247750 58247788 39 + 1.564 1.459 -0.360
ENSG00000100567 E013 29.0880608 0.0010582038 6.297262e-03 5.841131e-02 14 58247789 58247832 44 + 1.549 1.400 -0.513
ENSG00000100567 E014 18.4844003 0.0021872497 1.403151e-02 1.002219e-01 14 58252119 58252123 5 + 1.369 1.200 -0.590
ENSG00000100567 E015 52.7941458 0.0002795185 4.639275e-05 1.254209e-03 14 58252124 58252242 119 + 1.807 1.645 -0.551
ENSG00000100567 E016 55.1250011 0.0002743223 1.763718e-01 4.504692e-01 14 58257745 58257846 102 + 1.775 1.723 -0.173
ENSG00000100567 E017 0.1187032 0.0118335435 5.308319e-01   14 58257847 58257924 78 + 0.095 0.000 -9.182
ENSG00000100567 E018 45.8263262 0.0003276970 7.756524e-01 9.138060e-01 14 58257925 58257998 74 + 1.663 1.677 0.049
ENSG00000100567 E019 1.3603317 0.1106701452 4.485055e-01 7.224902e-01 14 58257999 58258454 456 + 0.297 0.432 0.795
ENSG00000100567 E020 23.4286895 0.0005866672 1.625013e-01 4.309516e-01 14 58260948 58260958 11 + 1.428 1.346 -0.284
ENSG00000100567 E021 24.4800283 0.0006490865 3.183376e-02 1.686123e-01 14 58260959 58260968 10 + 1.467 1.342 -0.432
ENSG00000100567 E022 39.6890873 0.0033241549 1.711625e-01 4.434652e-01 14 58260969 58261020 52 + 1.644 1.575 -0.235
ENSG00000100567 E023 1.2253537 0.0101144318 9.823491e-01 9.986626e-01 14 58263524 58263704 181 + 0.348 0.346 -0.013
ENSG00000100567 E024 49.1558016 0.0003020368 1.538124e-02 1.069449e-01 14 58263705 58263770 66 + 1.749 1.649 -0.337
ENSG00000100567 E025 52.0700312 0.0016821626 2.858041e-01 5.793959e-01 14 58267474 58267520 47 + 1.747 1.703 -0.149
ENSG00000100567 E026 66.9124469 0.0003247663 3.971269e-14 6.190359e-12 14 58267521 58268660 1140 + 1.663 1.944 0.951
ENSG00000100567 E027 23.3417298 0.0005981216 1.386177e-03 1.925369e-02 14 58269975 58270417 443 + 1.272 1.470 0.687
ENSG00000100567 E028 58.0059301 0.0003265023 5.975112e-01 8.233137e-01 14 58270418 58270485 68 + 1.780 1.762 -0.062
ENSG00000100567 E029 17.3843314 0.0018144506 3.114135e-02 1.663772e-01 14 58270486 58270933 448 + 1.177 1.332 0.546
ENSG00000100567 E030 44.9974579 0.0003382512 3.273569e-01 6.198886e-01 14 58270934 58270998 65 + 1.683 1.642 -0.139
ENSG00000100567 E031 27.8251982 0.0143059513 2.426783e-05 7.275491e-04 14 58270999 58271850 852 + 1.260 1.586 1.125
ENSG00000100567 E032 56.9368733 0.0002728240 3.239821e-01 6.165274e-01 14 58271851 58272316 466 + 1.741 1.781 0.136

Help

Please Click HERE to learn more details about the results from DEXseq.