ENSG00000100731

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000304743 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding protein_coding 9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 1.5203664 0.7811039 2.4582673 0.2237498 0.4496571 1.6415596 0.18416667 0.151150 0.269225 0.118075 0.754764595 0.001875887 FALSE TRUE
ENST00000439984 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding protein_coding 9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 0.9754258 0.5515461 0.4114448 0.2652805 0.4114448 -0.4140608 0.09779167 0.065850 0.028650 -0.037200 0.749568499 0.001875887 FALSE TRUE
ENST00000554691 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding protein_coding 9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 1.4789793 1.6079121 0.0000000 0.3764229 0.0000000 -7.3379894 0.19153333 0.292800 0.000000 -0.292800 0.003469526 0.001875887 FALSE TRUE
ENST00000556516 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding protein_coding_CDS_not_defined 9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 0.9657088 1.0320477 0.7517864 0.7671168 0.7517864 -0.4519628 0.08173333 0.086100 0.052350 -0.033750 0.805494354 0.001875887 FALSE TRUE
ENST00000557428 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding protein_coding_CDS_not_defined 9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 1.4828601 0.0000000 3.7254416 0.0000000 1.2669921 8.5451350 0.12974167 0.000000 0.314475 0.314475 0.019212525 0.001875887 FALSE FALSE
MSTRG.8750.11 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding   9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 0.7123881 0.0000000 2.1371642 0.0000000 0.4967786 7.7462887 0.07246667 0.000000 0.217400 0.217400 0.001875887 0.001875887 FALSE TRUE
MSTRG.8750.13 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding   9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 1.0442268 3.1326804 0.0000000 3.1326804 0.0000000 -8.2958517 0.05198333 0.155950 0.000000 -0.155950 0.802642498 0.001875887   FALSE
MSTRG.8750.17 ENSG00000100731 No_inf pgKDN_inf PCNX1 protein_coding   9.759025 8.755742 10.50575 3.784963 1.656367 0.2626031 0.9929382 1.1811658 0.9559906 0.4929612 0.6010122 -0.3022932 0.11941667 0.164475 0.110350 -0.054125 0.841754571 0.001875887 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100731 E001 0.1271363 0.0123960893 3.788657e-01   14 70907405 70907458 54 + 0.000 0.111 10.415
ENSG00000100731 E002 0.7254019 0.0141555362 6.823958e-01 0.8685848222 14 70907459 70907669 211 + 0.261 0.199 -0.507
ENSG00000100731 E003 0.4898235 0.0158376748 7.348500e-01   14 70907670 70907738 69 + 0.150 0.199 0.493
ENSG00000100731 E004 0.9788916 0.0172974734 6.346638e-01 0.8438615597 14 70907739 70908003 265 + 0.261 0.335 0.493
ENSG00000100731 E005 0.0000000       14 70942873 70942940 68 +      
ENSG00000100731 E006 0.0000000       14 70946882 70946914 33 +      
ENSG00000100731 E007 0.0000000       14 70946915 70947123 209 +      
ENSG00000100731 E008 1.1063650 0.1884481520 4.704569e-01 0.7381210934 14 70962226 70962331 106 + 0.261 0.389 0.815
ENSG00000100731 E009 0.0000000       14 70965365 70965369 5 +      
ENSG00000100731 E010 0.3810317 0.0244354535 5.330224e-02   14 70965370 70965432 63 + 0.000 0.272 14.362
ENSG00000100731 E011 1.0957895 0.4186804266 8.419496e-01 0.9432936750 14 70968198 70968243 46 + 0.308 0.335 0.173
ENSG00000100731 E012 2.1618451 0.4180505479 4.929965e-01 0.7550252437 14 70969021 70969110 90 + 0.565 0.390 -0.881
ENSG00000100731 E013 0.0000000       14 70969111 70969271 161 +      
ENSG00000100731 E014 0.2356421 0.0156253001 3.835131e-01   14 70969859 70969999 141 + 0.150 0.000 -14.068
ENSG00000100731 E015 7.1204083 0.0019987743 8.152243e-02 0.2935435078 14 70976942 70977743 802 + 0.976 0.794 -0.695
ENSG00000100731 E016 8.9148538 0.0015848705 1.907519e-02 0.1231360140 14 70977744 70978377 634 + 1.077 0.851 -0.843
ENSG00000100731 E017 1.5794713 0.1039037592 8.498694e-01 0.9467686009 14 70978378 70978419 42 + 0.423 0.389 -0.186
ENSG00000100731 E018 3.1778920 0.0144012029 6.457082e-01 0.8501277716 14 70978420 70978648 229 + 0.590 0.652 0.270
ENSG00000100731 E019 1.5651873 0.0237753036 1.755468e-01 0.4496124602 14 70988567 70988699 133 + 0.486 0.272 -1.244
ENSG00000100731 E020 1.8327453 0.0081877289 6.916951e-01 0.8736743933 14 70995741 70995843 103 + 0.423 0.482 0.300
ENSG00000100731 E021 0.8615054 0.0138091900 4.120838e-01 0.6935445765 14 70995844 70995858 15 + 0.209 0.335 0.908
ENSG00000100731 E022 1.7060174 0.0095669343 9.220113e-01 0.9757811720 14 70995859 70995925 67 + 0.423 0.438 0.078
ENSG00000100731 E023 2.1921830 0.0215018826 8.111385e-01 0.9305245249 14 71009634 71009724 91 + 0.486 0.522 0.171
ENSG00000100731 E024 0.1265070 0.0123878326 3.788395e-01   14 71009725 71009868 144 + 0.000 0.111 12.945
ENSG00000100731 E025 1.4431482 0.0093279085 2.360511e-01 0.5253220431 14 71011492 71011549 58 + 0.456 0.272 -1.092
ENSG00000100731 E026 0.1170040 0.0116926117 7.587340e-01   14 71011550 71012838 1289 + 0.081 0.000 -13.172
ENSG00000100731 E027 1.4366992 0.0095321024 6.663013e-02 0.2600203463 14 71012985 71012999 15 + 0.486 0.199 -1.829
ENSG00000100731 E028 2.7529961 0.0182669821 1.723844e-02 0.1148675730 14 71013000 71013030 31 + 0.692 0.335 -1.755
ENSG00000100731 E029 5.8460501 0.0023685401 3.679499e-05 0.0010266429 14 71013031 71013202 172 + 0.985 0.482 -2.092
ENSG00000100731 E030 4.9810368 0.0638885080 7.401407e-01 0.8968699089 14 71019009 71019162 154 + 0.789 0.752 -0.150
ENSG00000100731 E031 1.8320202 0.0075589463 6.913504e-01 0.8734690677 14 71023200 71023232 33 + 0.423 0.482 0.300
ENSG00000100731 E032 1.2155338 0.0117774278 9.213817e-01 0.9754608829 14 71026117 71026120 4 + 0.350 0.335 -0.092
ENSG00000100731 E033 2.0584029 0.0731542646 6.521570e-01 0.8534713313 14 71026121 71026194 74 + 0.514 0.438 -0.381
ENSG00000100731 E034 2.8110264 0.0750406865 6.049318e-01 0.8277788535 14 71026195 71026288 94 + 0.541 0.623 0.367
ENSG00000100731 E035 2.3330456 0.0155105483 3.458085e-01 0.6367147287 14 71026772 71026821 50 + 0.456 0.591 0.645
ENSG00000100731 E036 1.9648877 0.0149242080 2.465870e-01 0.5371984441 14 71026822 71026882 61 + 0.388 0.558 0.856
ENSG00000100731 E037 0.1271363 0.0123960893 3.788657e-01   14 71026883 71027202 320 + 0.000 0.111 12.945
ENSG00000100731 E038 1.0927770 0.1742572916 8.023785e-01 0.9263856916 14 71028700 71028724 25 + 0.308 0.335 0.173
ENSG00000100731 E039 1.6950949 0.1629237520 6.792751e-01 0.8674944417 14 71028725 71028791 67 + 0.456 0.390 -0.354
ENSG00000100731 E040 4.6045514 0.0473040147 4.207344e-01 0.6999348845 14 71033429 71033538 110 + 0.790 0.679 -0.451
ENSG00000100731 E041 4.2879855 0.0159903745 4.255192e-01 0.7045524091 14 71033931 71034036 106 + 0.673 0.774 0.410
ENSG00000100731 E042 3.2732292 0.0479081115 6.817644e-01 0.8682780953 14 71036065 71036157 93 + 0.654 0.591 -0.272
ENSG00000100731 E043 4.8247130 0.0030310486 1.342887e-01 0.3895194718 14 71045133 71045283 151 + 0.831 0.652 -0.729
ENSG00000100731 E044 2.9210148 0.0049032595 9.882399e-01 0.9999677249 14 71046964 71047105 142 + 0.590 0.591 0.008
ENSG00000100731 E045 3.6351196 0.0040213226 5.905348e-01 0.8188057365 14 71047807 71047959 153 + 0.692 0.623 -0.296
ENSG00000100731 E046 1.0824190 0.0113395491 2.258695e-01 0.5137695364 14 71047960 71047984 25 + 0.388 0.199 -1.314
ENSG00000100731 E047 1.0983763 0.0113490881 8.602417e-01 0.9515792048 14 71050652 71050657 6 + 0.308 0.335 0.171
ENSG00000100731 E048 2.3310024 0.0062643575 3.354502e-01 0.6272881778 14 71050658 71050760 103 + 0.456 0.591 0.645
ENSG00000100731 E049 3.7783949 0.0465194356 7.205270e-01 0.8874416213 14 71051883 71052012 130 + 0.654 0.705 0.213
ENSG00000100731 E050 0.1271363 0.0123960893 3.788657e-01   14 71053297 71053412 116 + 0.000 0.111 12.945
ENSG00000100731 E051 2.9483079 0.0074719384 2.220604e-01 0.5093246890 14 71055504 71055562 59 + 0.514 0.679 0.734
ENSG00000100731 E052 8.6634505 0.0360863418 6.618070e-01 0.8588315532 14 71057509 71057724 216 + 0.957 1.012 0.207
ENSG00000100731 E053 0.0000000       14 71060668 71060742 75 +      
ENSG00000100731 E054 10.9978402 0.0031726906 1.005524e-01 0.3311057294 14 71073545 71073798 254 + 1.133 0.987 -0.531
ENSG00000100731 E055 9.1681490 0.0016628715 2.326179e-02 0.1392608876 14 71076189 71076419 231 + 1.084 0.869 -0.803
ENSG00000100731 E056 0.0000000       14 71078651 71078739 89 +      
ENSG00000100731 E057 4.5768995 0.0259261277 7.470194e-02 0.2786867655 14 71088330 71088430 101 + 0.831 0.591 -0.993
ENSG00000100731 E058 7.4656217 0.0019049415 2.121337e-02 0.1317353774 14 71089192 71089342 151 + 1.012 0.774 -0.911
ENSG00000100731 E059 0.1186381 0.0118338732 7.586750e-01   14 71092554 71093845 1292 + 0.081 0.000 -13.172
ENSG00000100731 E060 12.1639413 0.0011831338 9.153316e-01 0.9734944708 14 71101990 71102220 231 + 1.120 1.111 -0.032
ENSG00000100731 E061 6.2880178 0.0022237533 1.918595e-01 0.4716063275 14 71103395 71103476 82 + 0.915 0.774 -0.549
ENSG00000100731 E062 8.1327106 0.0017689938 6.522171e-01 0.8534713313 14 71103477 71103588 112 + 0.976 0.932 -0.164
ENSG00000100731 E063 5.8699354 0.0068675770 3.866906e-01 0.6725459750 14 71103589 71103669 81 + 0.789 0.885 0.373
ENSG00000100731 E064 15.6102137 0.0010936488 6.083123e-01 0.8294245441 14 71105235 71105440 206 + 1.200 1.237 0.130
ENSG00000100731 E065 23.3675006 0.0006530071 9.692434e-01 0.9936412263 14 71108604 71109019 416 + 1.382 1.384 0.008
ENSG00000100731 E066 5.2240368 0.0027874218 7.928596e-01 0.9209615701 14 71109020 71109046 27 + 0.804 0.774 -0.120
ENSG00000100731 E067 14.8623809 0.0049010544 6.770959e-01 0.8661023382 14 71109452 71109592 141 + 1.183 1.215 0.113
ENSG00000100731 E068 6.7081258 0.0224203145 7.621369e-01 0.9072585480 14 71109795 71109831 37 + 0.869 0.901 0.124
ENSG00000100731 E069 14.0805565 0.0009252799 8.013077e-02 0.2905831789 14 71109832 71109982 151 + 1.113 1.244 0.468
ENSG00000100731 E070 103.5651260 0.0002731083 1.224964e-05 0.0004070684 14 71109983 71115382 5400 + 1.964 2.075 0.374

Help

Please Click HERE to learn more details about the results from DEXseq.