ENSG00000100938

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000399440 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding protein_coding 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 6.1989852 2.104307 7.142172 2.10430748 2.4862405 1.75819614 0.19749167 0.046775 0.252200 0.205425 0.17431727 0.01327121 FALSE TRUE
ENST00000420554 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding protein_coding 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 1.9747220 2.333979 2.230817 0.98700908 0.7704436 -0.06493433 0.05676667 0.049050 0.073025 0.023975 0.89176263 0.01327121 FALSE TRUE
ENST00000456667 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding protein_coding 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 0.6996626 0.000000 2.098988 0.00000000 2.0989878 7.72040695 0.01954167 0.000000 0.058625 0.058625 0.81796357 0.01327121 FALSE TRUE
ENST00000558007 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding retained_intron 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 8.0618196 12.213157 0.980027 1.70382463 0.9800270 -3.62600533 0.19529167 0.266000 0.033875 -0.232125 0.01327121 0.01327121 FALSE TRUE
ENST00000558483 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding protein_coding 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 2.9136006 3.010123 3.894360 3.01012291 2.2606889 0.37047888 0.08115000 0.061525 0.138500 0.076975 0.76228827 0.01327121 FALSE TRUE
ENST00000558701 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding protein_coding_CDS_not_defined 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 1.6850851 1.261053 3.794202 1.26105315 2.2954128 1.58156952 0.04794167 0.028025 0.115800 0.087775 0.72392446 0.01327121   FALSE
ENST00000559606 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding retained_intron 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 3.0388452 4.471808 2.095718 1.18411315 0.5966103 -1.08976828 0.07915833 0.094950 0.066375 -0.028575 0.84670028 0.01327121   FALSE
ENST00000559801 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding retained_intron 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 1.3777297 3.292573 0.000000 1.31971227 0.0000000 -8.36744657 0.03174167 0.069525 0.000000 -0.069525 0.06258913 0.01327121   FALSE
ENST00000560517 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding protein_coding_CDS_not_defined 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 2.9443346 4.666854 2.094476 0.77333474 0.4411855 -1.15207723 0.07847500 0.100450 0.067200 -0.033250 0.79155071 0.01327121   FALSE
ENST00000561038 ENSG00000100938 No_inf pgKDN_inf GMPR2 protein_coding nonsense_mediated_decay 36.84839 46.20511 30.30669 1.344366 2.262844 -0.6082524 2.0340420 2.906324 1.447648 0.05636329 0.6339656 -1.00050855 0.05674167 0.063125 0.046825 -0.016300 0.82554667 0.01327121 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100938 E001 0.2448930 0.0163290126 0.875341695   14 24232422 24232441 20 + 0.104 0.087 -0.283
ENSG00000100938 E002 0.6160133 0.0163594784 0.825868673 0.93693429 14 24232442 24232489 48 + 0.188 0.222 0.302
ENSG00000100938 E003 1.8445471 0.0078140356 0.900457526 0.96768211 14 24232490 24232634 145 + 0.461 0.443 -0.091
ENSG00000100938 E004 0.9903761 0.0637998516 0.663797937 0.86015275 14 24232635 24232635 1 + 0.258 0.324 0.453
ENSG00000100938 E005 1.1168832 0.1366707151 0.488660552 0.75191630 14 24232636 24232641 6 + 0.258 0.368 0.716
ENSG00000100938 E006 2.4760737 0.0063726387 0.366717839 0.65537493 14 24232642 24232665 24 + 0.461 0.589 0.610
ENSG00000100938 E007 2.9670583 0.0058858356 0.458567640 0.73045688 14 24232666 24232675 10 + 0.535 0.636 0.454
ENSG00000100938 E008 3.5920402 0.0052528093 0.251916517 0.54318351 14 24232676 24232685 10 + 0.568 0.717 0.643
ENSG00000100938 E009 5.1824406 0.0374764283 0.570575530 0.80700600 14 24232686 24232749 64 + 0.747 0.816 0.273
ENSG00000100938 E010 3.5840185 0.0660795370 0.511364249 0.76854259 14 24232750 24232788 39 + 0.599 0.698 0.427
ENSG00000100938 E011 0.6165478 0.0148483673 0.823039867 0.93566477 14 24232789 24232847 59 + 0.188 0.222 0.302
ENSG00000100938 E012 0.1176306 0.0118398541 0.439031883   14 24232893 24232897 5 + 0.104 0.000 -10.442
ENSG00000100938 E013 0.1176306 0.0118398541 0.439031883   14 24232898 24232900 3 + 0.104 0.000 -10.442
ENSG00000100938 E014 0.1176306 0.0118398541 0.439031883   14 24232901 24232901 1 + 0.104 0.000 -10.442
ENSG00000100938 E015 0.6256726 0.0153945265 0.251362279 0.54257807 14 24232902 24232917 16 + 0.104 0.276 1.717
ENSG00000100938 E016 0.8609339 0.2664163409 0.831630342 0.93923908 14 24232918 24232922 5 + 0.258 0.276 0.133
ENSG00000100938 E017 0.9877879 0.1154935342 0.667500344 0.86155563 14 24232923 24232928 6 + 0.258 0.324 0.454
ENSG00000100938 E018 1.2325548 0.3247564413 0.629107017 0.84097672 14 24232929 24232946 18 + 0.318 0.368 0.303
ENSG00000100938 E019 1.2325548 0.3247564413 0.629107017 0.84097672 14 24232947 24232947 1 + 0.318 0.368 0.303
ENSG00000100938 E020 3.0707753 0.1780549999 0.814177807 0.93209369 14 24232948 24232977 30 + 0.628 0.589 -0.168
ENSG00000100938 E021 3.1769563 0.0043145486 0.369190398 0.65744536 14 24232978 24233218 241 + 0.679 0.564 -0.506
ENSG00000100938 E022 14.9899719 0.0023319318 0.843304149 0.94397837 14 24233219 24233340 122 + 1.207 1.194 -0.046
ENSG00000100938 E023 13.4173230 0.0017806894 0.691474208 0.87357921 14 24233479 24233586 108 + 1.136 1.169 0.116
ENSG00000100938 E024 5.5245405 0.0027152256 0.821063187 0.93501450 14 24233587 24233593 7 + 0.824 0.801 -0.091
ENSG00000100938 E025 5.3955140 0.0055097725 0.716425930 0.88570998 14 24233594 24233598 5 + 0.824 0.786 -0.152
ENSG00000100938 E026 0.6351480 0.0193642209 0.035868645 0.18166396 14 24233599 24233675 77 + 0.000 0.324 12.092
ENSG00000100938 E027 0.7514889 0.0147526604 0.147722046 0.40911305 14 24234107 24234112 6 + 0.104 0.324 2.039
ENSG00000100938 E028 3.6028932 0.0073639293 0.129202762 0.38135072 14 24234113 24234241 129 + 0.535 0.735 0.869
ENSG00000100938 E029 6.8501628 0.0191664945 0.013473944 0.09756849 14 24235374 24235736 363 + 0.703 0.995 1.131
ENSG00000100938 E030 12.9831549 0.0011876357 0.291434479 0.58495133 14 24235737 24235820 84 + 1.185 1.106 -0.283
ENSG00000100938 E031 11.3872505 0.0015281187 0.276302309 0.56982597 14 24235967 24236041 75 + 1.136 1.049 -0.314
ENSG00000100938 E032 9.6819519 0.0031580184 0.438838639 0.71486071 14 24236042 24236095 54 + 1.062 0.995 -0.247
ENSG00000100938 E033 10.1097603 0.0207823733 0.559071195 0.80040602 14 24236096 24236140 45 + 1.008 1.066 0.214
ENSG00000100938 E034 1.2541191 0.0321902235 0.107999562 0.34460441 14 24236975 24237041 67 + 0.188 0.443 1.717
ENSG00000100938 E035 1.7424617 0.0148717429 0.216397441 0.50251801 14 24237042 24237070 29 + 0.318 0.508 1.039
ENSG00000100938 E036 16.9624258 0.0050489303 0.011240079 0.08683891 14 24237071 24237152 82 + 1.344 1.162 -0.638
ENSG00000100938 E037 13.7715886 0.0136577842 0.026777629 0.15181590 14 24237245 24237272 28 + 1.262 1.075 -0.669
ENSG00000100938 E038 18.6845447 0.0008417886 0.017761870 0.11724748 14 24237273 24237351 79 + 1.369 1.218 -0.529
ENSG00000100938 E039 8.3680184 0.0016641008 0.881432868 0.96010066 14 24237520 24237562 43 + 0.959 0.975 0.058
ENSG00000100938 E040 6.3695027 0.0023211509 0.001425817 0.01966250 14 24237563 24237953 391 + 0.627 0.985 1.417
ENSG00000100938 E041 2.1383832 0.0072269927 0.003275958 0.03691716 14 24238188 24238245 58 + 0.188 0.636 2.624
ENSG00000100938 E042 2.4960921 0.0057659851 0.065747538 0.25828740 14 24238246 24238330 85 + 0.371 0.636 1.302
ENSG00000100938 E043 0.0000000       14 24238331 24238378 48 +      
ENSG00000100938 E044 0.0000000       14 24238379 24238405 27 +      
ENSG00000100938 E045 0.0000000       14 24238406 24238588 183 +      
ENSG00000100938 E046 0.0000000       14 24238589 24238596 8 +      
ENSG00000100938 E047 0.0000000       14 24238597 24238626 30 +      
ENSG00000100938 E048 0.0000000       14 24238627 24238748 122 +      
ENSG00000100938 E049 0.0000000       14 24238749 24238769 21 +      
ENSG00000100938 E050 0.0000000       14 24238770 24238803 34 +      
ENSG00000100938 E051 0.0000000       14 24238804 24238905 102 +      
ENSG00000100938 E052 0.0000000       14 24238906 24238957 52 +      
ENSG00000100938 E053 0.0000000       14 24238958 24239242 285 +      

Help

Please Click HERE to learn more details about the results from DEXseq.