ENSG00000100994

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000216962 ENSG00000100994 No_inf pgKDN_inf PYGB protein_coding protein_coding 74.9431 43.42096 96.58188 0.7724325 1.40522 1.153178 51.711196 23.194481 70.915154 2.582763 1.4859430 1.6118939 0.6623833 0.5329 0.734750 0.201850 0.0330261 0.0330261 FALSE TRUE
ENST00000428458 ENSG00000100994 No_inf pgKDN_inf PYGB protein_coding protein_coding 74.9431 43.42096 96.58188 0.7724325 1.40522 1.153178 9.557004 5.018627 15.687455 3.122549 1.1486237 1.6422943 0.1227167 0.1133 0.162075 0.048775 0.6032602 0.0330261 FALSE TRUE
ENST00000471359 ENSG00000100994 No_inf pgKDN_inf PYGB protein_coding protein_coding_CDS_not_defined 74.9431 43.42096 96.58188 0.7724325 1.40522 1.153178 9.064951 7.032641 8.427533 1.028302 0.9572636 0.2607048 0.1293833 0.1619 0.087350 -0.074550 0.3903737 0.0330261   FALSE
MSTRG.18094.3 ENSG00000100994 No_inf pgKDN_inf PYGB protein_coding   74.9431 43.42096 96.58188 0.7724325 1.40522 1.153178 1.059213 2.611065 0.000000 1.745869 0.0000000 -8.0340092 0.0229250 0.0618 0.000000 -0.061800 0.3628599 0.0330261 TRUE TRUE
MSTRG.18094.5 ENSG00000100994 No_inf pgKDN_inf PYGB protein_coding   74.9431 43.42096 96.58188 0.7724325 1.40522 1.153178 3.550735 5.564147 1.551733 2.572501 0.9869183 -1.8356031 0.0626000 0.1301 0.015875 -0.114225 0.4676784 0.0330261 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000100994 E001 1.553982 0.0096620834 0.1876579827 0.465833014 20 25248085 25248085 1 + 0.448 0.238 -1.311
ENSG00000100994 E002 2.979608 0.0047540874 0.0237894695 0.141178787 20 25248086 25248110 25 + 0.664 0.321 -1.726
ENSG00000100994 E003 18.761181 0.0007221142 0.0778363653 0.285445583 20 25248111 25248259 149 + 1.306 1.182 -0.437
ENSG00000100994 E004 29.079515 0.0006855548 0.5040753435 0.763348211 20 25248260 25248421 162 + 1.462 1.429 -0.111
ENSG00000100994 E005 23.236596 0.0005864467 0.5792204770 0.812052956 20 25259237 25259338 102 + 1.343 1.386 0.148
ENSG00000100994 E006 30.589247 0.0005092474 0.7451183649 0.899163509 20 25269129 25269207 79 + 1.464 1.490 0.088
ENSG00000100994 E007 39.276788 0.0004111790 0.9767989042 0.996306065 20 25271383 25271486 104 + 1.576 1.582 0.020
ENSG00000100994 E008 43.383993 0.0003343735 0.0029697742 0.034298030 20 25274592 25274723 132 + 1.662 1.519 -0.485
ENSG00000100994 E009 39.853500 0.0003749293 0.0003332270 0.006328262 20 25276646 25276757 112 + 1.636 1.452 -0.629
ENSG00000100994 E010 32.832071 0.0004464008 0.0352043432 0.179615083 20 25277244 25277326 83 + 1.536 1.423 -0.388
ENSG00000100994 E011 47.988773 0.0002839427 0.2648811532 0.557898235 20 25278319 25278462 144 + 1.677 1.633 -0.151
ENSG00000100994 E012 39.759621 0.0019735311 0.1773887030 0.451999822 20 25279057 25279149 93 + 1.603 1.538 -0.223
ENSG00000100994 E013 52.050909 0.0081802197 0.0241557468 0.142371890 20 25280266 25280412 147 + 1.734 1.610 -0.423
ENSG00000100994 E014 63.180579 0.0026949291 0.2668063121 0.560198696 20 25280949 25281110 162 + 1.793 1.751 -0.143
ENSG00000100994 E015 22.181445 0.0006575309 0.3474667762 0.638118806 20 25281111 25281112 2 + 1.356 1.300 -0.196
ENSG00000100994 E016 56.758420 0.0023604378 0.1610021887 0.429089887 20 25282033 25282147 115 + 1.753 1.694 -0.197
ENSG00000100994 E017 52.716186 0.0025441123 0.0455974046 0.208962551 20 25283176 25283277 102 + 1.731 1.640 -0.308
ENSG00000100994 E018 51.688269 0.0004655290 0.7839605674 0.916834232 20 25284104 25284251 148 + 1.696 1.691 -0.017
ENSG00000100994 E019 37.120898 0.0004334886 0.7667661728 0.909590450 20 25288425 25288483 59 + 1.546 1.569 0.077
ENSG00000100994 E020 1.461183 0.0091104949 0.4629874969 0.733107629 20 25289848 25289930 83 + 0.333 0.451 0.663
ENSG00000100994 E021 63.922963 0.0026922742 0.0159685049 0.109630766 20 25290481 25290622 142 + 1.816 1.713 -0.348
ENSG00000100994 E022 2.341916 0.0364987533 0.0287681982 0.158924921 20 25291893 25292047 155 + 0.365 0.700 1.608
ENSG00000100994 E023 80.807805 0.0002136707 0.8359892391 0.941142265 20 25292406 25292613 208 + 1.885 1.885 0.000
ENSG00000100994 E024 7.353445 0.0020527386 0.0013585158 0.018957358 20 25293901 25294157 257 + 0.761 1.090 1.245
ENSG00000100994 E025 59.657895 0.0093937247 0.0981795166 0.326824716 20 25294158 25294292 135 + 1.721 1.819 0.329
ENSG00000100994 E026 38.175458 0.0187400670 0.0344566957 0.177314132 20 25295604 25295670 67 + 1.506 1.668 0.552
ENSG00000100994 E027 509.382443 0.0008860198 0.0001118892 0.002609007 20 25296370 25297672 1303 + 2.659 2.721 0.209
ENSG00000100994 E028 41.569679 0.0037388587 0.0097701022 0.079097424 20 25297673 25297742 70 + 1.549 1.694 0.496
ENSG00000100994 E029 62.205210 0.0003388265 0.3282237589 0.620723735 20 25297743 25298012 270 + 1.758 1.804 0.157

Help

Please Click HERE to learn more details about the results from DEXseq.