ENSG00000101346

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375749 ENSG00000101346 No_inf pgKDN_inf POFUT1 protein_coding protein_coding 24.90913 16.35135 28.79935 0.515292 1.152033 0.8162455 12.524549 5.407030 17.04045 0.6269422 0.6984926 1.6542360 0.4804250 0.330800 0.593525 0.262725 3.541905e-02 2.885719e-09 FALSE TRUE
ENST00000434904 ENSG00000101346 No_inf pgKDN_inf POFUT1 protein_coding protein_coding_CDS_not_defined 24.90913 16.35135 28.79935 0.515292 1.152033 0.8162455 9.126411 6.093459 11.70934 0.3097469 1.1760340 0.9411927 0.3664333 0.372100 0.404675 0.032575 8.898036e-01 2.885719e-09   FALSE
MSTRG.18134.6 ENSG00000101346 No_inf pgKDN_inf POFUT1 protein_coding   24.90913 16.35135 28.79935 0.515292 1.152033 0.8162455 2.576742 4.297489 0.00000 0.7493049 0.0000000 -8.7507031 0.1250667 0.262875 0.000000 -0.262875 2.885719e-09 2.885719e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000101346 E001 0.2441377 0.0164713117 0.697211022   20 32207880 32207885 6 + 0.076 0.119 0.727
ENSG00000101346 E002 0.2441377 0.0164713117 0.697211022   20 32207886 32207892 7 + 0.076 0.119 0.727
ENSG00000101346 E003 2.1761931 0.0066298141 0.700382889 0.87795216 20 32207893 32207934 42 + 0.516 0.461 -0.273
ENSG00000101346 E004 6.2754160 0.0027006475 0.182112805 0.45820452 20 32207935 32208065 131 + 0.905 0.758 -0.576
ENSG00000101346 E005 6.5799255 0.0428353188 0.647194435 0.85082106 20 32210071 32210192 122 + 0.851 0.899 0.185
ENSG00000101346 E006 10.1716522 0.0248574898 0.761677227 0.90705011 20 32215269 32215451 183 + 1.052 1.019 -0.121
ENSG00000101346 E007 6.2668063 0.0025673079 0.181774865 0.45776818 20 32216609 32216664 56 + 0.905 0.758 -0.576
ENSG00000101346 E008 6.7129437 0.0021212707 0.009092139 0.07553534 20 32216665 32216721 57 + 0.972 0.679 -1.148
ENSG00000101346 E009 0.6269010 0.2036824327 0.096164482 0.32299517 20 32217008 32217923 916 + 0.076 0.354 2.726
ENSG00000101346 E010 0.2542726 0.2877329269 0.160435734   20 32222749 32222833 85 + 0.000 0.212 10.840
ENSG00000101346 E011 14.5645438 0.0020632210 0.016237406 0.11072466 20 32228263 32228455 193 + 1.249 1.057 -0.688
ENSG00000101346 E012 4.1292166 0.0035173852 0.951932153 0.98790665 20 32230819 32230821 3 + 0.699 0.707 0.035
ENSG00000101346 E013 15.8382771 0.0012801337 0.284399721 0.57820518 20 32230822 32231061 240 + 1.184 1.263 0.279
ENSG00000101346 E014 0.2537694 0.0159690729 0.113088453   20 32231062 32231336 275 + 0.000 0.212 11.656
ENSG00000101346 E015 26.1966064 0.0024333335 0.734715784 0.89474481 20 32234473 32234913 441 + 1.432 1.413 -0.068
ENSG00000101346 E016 12.1317415 0.0012000456 0.881203414 0.96003909 20 32234914 32235122 209 + 1.114 1.102 -0.041
ENSG00000101346 E017 98.3574489 0.0003083832 0.845749826 0.94512714 20 32235123 32236432 1310 + 1.985 1.991 0.022
ENSG00000101346 E018 174.8939550 0.0001433791 0.422320625 0.70157828 20 32236433 32237794 1362 + 2.229 2.245 0.053
ENSG00000101346 E019 63.5712549 0.0002582638 0.352888400 0.64282532 20 32237795 32238658 864 + 1.786 1.821 0.116

Help

Please Click HERE to learn more details about the results from DEXseq.