ENSG00000101439

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376925 ENSG00000101439 No_inf pgKDN_inf CST3 protein_coding protein_coding 470.2122 700.8331 353.2919 8.634455 7.215427 -0.98819 376.88332 587.5387 260.81725 17.39202 4.311351 -1.1716138 0.7896667 0.837900 0.739325 -0.098575 0.008437528 0.008437528 FALSE  
ENST00000398409 ENSG00000101439 No_inf pgKDN_inf CST3 protein_coding protein_coding 470.2122 700.8331 353.2919 8.634455 7.215427 -0.98819 92.19178 112.0173 91.26387 10.31253 8.959184 -0.2955768 0.2077083 0.160275 0.257225 0.096950 0.047646104 0.008437528 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000101439 E001 17.93338 7.535494e-04 0.000135676 0.00305025 20 23626706 23629465 2760 - 1.409 1.142 -0.937
ENSG00000101439 E002 516.10587 9.264807e-05 0.390034660 0.67551791 20 23633657 23633913 257 - 2.680 2.669 -0.037
ENSG00000101439 E003 429.26517 6.538218e-05 0.649068839 0.85208059 20 23633914 23633999 86 - 2.588 2.594 0.023
ENSG00000101439 E004 523.03666 5.559588e-05 0.024010118 0.14189832 20 23635254 23635367 114 - 2.657 2.686 0.099
ENSG00000101439 E005 700.71370 4.809762e-05 0.247857606 0.53860775 20 23637620 23637932 313 - 2.813 2.801 -0.040
ENSG00000101439 E006 47.57997 3.017626e-04 0.959610966 0.99055786 20 23637933 23637955 23 - 1.647 1.645 -0.008
ENSG00000101439 E007 13.98715 2.274724e-02 0.150600136 0.41319184 20 23638412 23638473 62 - 1.024 1.176 0.551

Help

Please Click HERE to learn more details about the results from DEXseq.