ENSG00000101473

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000217455 ENSG00000101473 No_inf pgKDN_inf ACOT8 protein_coding protein_coding 17.66241 19.45512 18.0539 0.9485443 2.503857 -0.1077818 10.4061215 12.6109139 8.2441883 0.7836411 2.8692939 -0.6126181 0.59441667 0.655600 0.440325 -0.215275 0.77664201 0.01598035 FALSE  
ENST00000461272 ENSG00000101473 No_inf pgKDN_inf ACOT8 protein_coding nonsense_mediated_decay 17.66241 19.45512 18.0539 0.9485443 2.503857 -0.1077818 1.5729020 0.9910771 2.7804091 0.5725126 2.1914841 1.4789236 0.09694167 0.052250 0.185025 0.132775 0.98752434 0.01598035 TRUE  
ENST00000484783 ENSG00000101473 No_inf pgKDN_inf ACOT8 protein_coding retained_intron 17.66241 19.45512 18.0539 0.9485443 2.503857 -0.1077818 0.4768033 0.0000000 0.9371928 0.0000000 0.3294391 6.5655862 0.02725833 0.000000 0.053900 0.053900 0.07694565 0.01598035 FALSE  
ENST00000484975 ENSG00000101473 No_inf pgKDN_inf ACOT8 protein_coding retained_intron 17.66241 19.45512 18.0539 0.9485443 2.503857 -0.1077818 1.0454745 2.0636812 0.1764513 0.2915806 0.1764513 -3.4753236 0.05547500 0.105200 0.007075 -0.098125 0.01598035 0.01598035 FALSE  
ENST00000487205 ENSG00000101473 No_inf pgKDN_inf ACOT8 protein_coding protein_coding 17.66241 19.45512 18.0539 0.9485443 2.503857 -0.1077818 0.6524161 0.0000000 1.9572482 0.0000000 1.1503036 7.6200352 0.03004167 0.000000 0.090125 0.090125 0.39636470 0.01598035 FALSE  
ENST00000488679 ENSG00000101473 No_inf pgKDN_inf ACOT8 protein_coding nonsense_mediated_decay 17.66241 19.45512 18.0539 0.9485443 2.503857 -0.1077818 2.0370566 1.9883357 2.1985374 1.2775883 1.3588167 0.1442923 0.10637500 0.094375 0.110150 0.015775 1.00000000 0.01598035 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000101473 E001 0.0000000       20 45841721 45841725 5 -      
ENSG00000101473 E002 0.0000000       20 45841726 45841729 4 -      
ENSG00000101473 E003 0.0000000       20 45841730 45841737 8 -      
ENSG00000101473 E004 0.0000000       20 45841738 45841764 27 -      
ENSG00000101473 E005 0.0000000       20 45841765 45841956 192 -      
ENSG00000101473 E006 0.0000000       20 45842023 45842746 724 -      
ENSG00000101473 E007 1.1044824 0.0115849300 0.90879388 0.97110263 20 45842747 45843398 652 - 0.329 0.313 -0.105
ENSG00000101473 E008 1.6316578 0.0158408240 0.03869237 0.19028541 20 45843399 45843526 128 - 0.195 0.521 2.032
ENSG00000101473 E009 18.1476367 0.0009045668 0.23466929 0.52373805 20 45843527 45843721 195 - 1.228 1.306 0.273
ENSG00000101473 E010 1.6124885 0.3383427821 0.64572969 0.85012777 20 45843722 45843722 1 - 0.330 0.462 0.741
ENSG00000101473 E011 1.9753930 0.1445368913 0.77979426 0.91512736 20 45843723 45843772 50 - 0.432 0.493 0.309
ENSG00000101473 E012 5.4596843 0.0026160489 0.13923181 0.39671026 20 45843773 45844262 490 - 0.697 0.865 0.672
ENSG00000101473 E013 18.1351001 0.0206566313 0.31133065 0.60450399 20 45844263 45844420 158 - 1.325 1.237 -0.309
ENSG00000101473 E014 13.6141964 0.0013010138 0.24920729 0.54013606 20 45848450 45848532 83 - 1.205 1.122 -0.297
ENSG00000101473 E015 20.5314094 0.0035374821 0.51382703 0.77063339 20 45848533 45848675 143 - 1.348 1.310 -0.133
ENSG00000101473 E016 2.7648362 0.0053476620 0.00321345 0.03635709 20 45848676 45849110 435 - 0.268 0.700 2.236
ENSG00000101473 E017 0.0000000       20 45853420 45853421 2 -      
ENSG00000101473 E018 0.9907493 0.0141012958 0.77949660 0.91500539 20 45853422 45853922 501 - 0.268 0.313 0.310
ENSG00000101473 E019 0.8638036 0.2795752178 0.92083325 0.97524654 20 45853923 45853979 57 - 0.268 0.266 -0.014
ENSG00000101473 E020 0.5078243 0.2323873459 0.13903162 0.39649594 20 45853980 45853984 5 - 0.000 0.266 11.024
ENSG00000101473 E021 13.5943271 0.0013505330 0.12109544 0.36825335 20 45855159 45855292 134 - 1.220 1.108 -0.401
ENSG00000101473 E022 1.3503178 0.0098908208 0.84696021 0.94568449 20 45856783 45857187 405 - 0.384 0.355 -0.164
ENSG00000101473 E023 12.1867221 0.0015884539 0.97079987 0.99422973 20 45857188 45857405 218 - 1.111 1.115 0.013

Help

Please Click HERE to learn more details about the results from DEXseq.