ENSG00000101577

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261596 ENSG00000101577 No_inf pgKDN_inf LPIN2 protein_coding protein_coding 15.48379 11.21554 17.03717 0.2636284 0.5046594 0.6027469 0.7616628 0.0000000 1.859600 0.0000000 0.2834460 7.5465857 0.04403333 0.000000 0.110475 0.110475 0.0028051113 0.0005657561 FALSE TRUE
ENST00000677752 ENSG00000101577 No_inf pgKDN_inf LPIN2 protein_coding protein_coding 15.48379 11.21554 17.03717 0.2636284 0.5046594 0.6027469 2.5669487 5.6561202 0.687037 0.2260298 0.4684654 -3.0230540 0.20738333 0.504625 0.039775 -0.464850 0.0005657561 0.0005657561 FALSE TRUE
ENST00000697041 ENSG00000101577 No_inf pgKDN_inf LPIN2 protein_coding protein_coding 15.48379 11.21554 17.03717 0.2636284 0.5046594 0.6027469 5.7161769 4.0394290 6.523825 0.2875680 0.4354736 0.6902093 0.36812500 0.361100 0.382425 0.021325 0.9611591260 0.0005657561 FALSE TRUE
MSTRG.13588.6 ENSG00000101577 No_inf pgKDN_inf LPIN2 protein_coding   15.48379 11.21554 17.03717 0.2636284 0.5046594 0.6027469 3.7721951 0.8124960 4.691313 0.1716213 0.2406636 2.5149831 0.22210000 0.071600 0.274850 0.203250 0.0278733158 0.0005657561 TRUE TRUE
MSTRG.13588.7 ENSG00000101577 No_inf pgKDN_inf LPIN2 protein_coding   15.48379 11.21554 17.03717 0.2636284 0.5046594 0.6027469 2.6668091 0.7074961 3.275391 0.1274953 0.1065764 2.1950222 0.15839167 0.062750 0.192475 0.129725 0.1483775712 0.0005657561 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000101577 E001 0.0000000       18 2885296 2885434 139 -      
ENSG00000101577 E002 0.8243062 0.0149606389 8.955571e-03 7.468838e-02 18 2916994 2916998 5 - 0.391 0.000 -11.279
ENSG00000101577 E003 0.9430094 0.0183676678 4.794234e-03 4.808856e-02 18 2916999 2917006 8 - 0.426 0.000 -13.649
ENSG00000101577 E004 4.8457176 0.0085349632 2.020686e-01 4.845441e-01 18 2917007 2917108 102 - 0.808 0.701 -0.431
ENSG00000101577 E005 177.7090636 0.0058710125 2.255733e-21 6.952041e-19 18 2917109 2920104 2996 - 2.106 2.382 0.924
ENSG00000101577 E006 9.9371827 0.0078143809 8.589784e-02 3.034329e-01 18 2920105 2920437 333 - 1.081 0.970 -0.408
ENSG00000101577 E007 9.1507513 0.0023556634 7.246869e-04 1.165680e-02 18 2920438 2920777 340 - 1.103 0.829 -1.023
ENSG00000101577 E008 4.3505183 0.0361143054 1.171507e-01 3.614236e-01 18 2920778 2920881 104 - 0.793 0.619 -0.723
ENSG00000101577 E009 0.0000000       18 2921533 2921647 115 -      
ENSG00000101577 E010 0.3624961 0.0164063231 7.080991e-01   18 2921757 2922046 290 - 0.151 0.110 -0.538
ENSG00000101577 E011 6.3764135 0.1322663930 3.715412e-02 1.856123e-01 18 2922047 2922199 153 - 0.971 0.675 -1.160
ENSG00000101577 E012 33.1833587 0.0005080877 1.170495e-27 5.739043e-25 18 2922200 2923774 1575 - 1.699 1.126 -1.988
ENSG00000101577 E013 7.5133732 0.0375379531 2.287798e-01 5.174891e-01 18 2923775 2923861 87 - 0.970 0.865 -0.401
ENSG00000101577 E014 13.4595051 0.0012221537 4.029236e-14 6.262617e-12 18 2923862 2924397 536 - 1.335 0.701 -2.360
ENSG00000101577 E015 9.5839140 0.0233169481 1.844164e-01 4.615722e-01 18 2924398 2924540 143 - 1.058 0.970 -0.324
ENSG00000101577 E016 2.9461332 0.0299468174 4.305783e-01 7.084228e-01 18 2924541 2924546 6 - 0.518 0.675 0.703
ENSG00000101577 E017 6.9756279 0.0525062034 5.457875e-01 7.916231e-01 18 2925224 2925368 145 - 0.835 0.970 0.514
ENSG00000101577 E018 6.3698632 0.0022507340 4.946668e-01 7.559605e-01 18 2926723 2926805 83 - 0.808 0.928 0.462
ENSG00000101577 E019 6.1076934 0.0025472854 9.157605e-01 9.735788e-01 18 2927722 2927811 90 - 0.822 0.881 0.231
ENSG00000101577 E020 9.6936892 0.0028815419 5.547998e-07 2.737655e-05 18 2927812 2928590 779 - 1.169 0.725 -1.675
ENSG00000101577 E021 4.1377753 0.0045288545 6.355056e-01 8.444702e-01 18 2928591 2928660 70 - 0.714 0.701 -0.052
ENSG00000101577 E022 1.3329174 0.0275358619 5.610690e-01 8.015430e-01 18 2928661 2928720 60 - 0.391 0.332 -0.345
ENSG00000101577 E023 5.8383061 0.0289988546 5.060386e-01 7.647580e-01 18 2929065 2929158 94 - 0.848 0.810 -0.148
ENSG00000101577 E024 8.6220920 0.0021227765 4.756390e-02 2.144013e-01 18 2931256 2931443 188 - 0.861 1.097 0.877
ENSG00000101577 E025 5.7851794 0.0057778914 1.027129e-01 3.350408e-01 18 2934351 2934450 100 - 0.714 0.942 0.895
ENSG00000101577 E026 12.0551809 0.0011547144 5.688355e-01 8.060421e-01 18 2937692 2938037 346 - 1.110 1.116 0.022
ENSG00000101577 E027 5.8645316 0.0025876416 7.128731e-01 8.840472e-01 18 2939480 2939603 124 - 0.793 0.881 0.342
ENSG00000101577 E028 3.4654708 0.0042125401 4.510055e-02 2.076890e-01 18 2940605 2940712 108 - 0.489 0.790 1.310
ENSG00000101577 E029 0.0000000       18 2951055 2951134 80 -      
ENSG00000101577 E030 0.0000000       18 2951135 2951161 27 -      
ENSG00000101577 E031 0.0000000       18 2951162 2951356 195 -      
ENSG00000101577 E032 0.9802085 0.0123422587 7.899005e-01 9.194452e-01 18 2954504 2954599 96 - 0.263 0.332 0.462
ENSG00000101577 E033 1.1011453 0.0183616486 9.621740e-01 9.917362e-01 18 2960649 2960849 201 - 0.310 0.332 0.140
ENSG00000101577 E034 0.0000000       18 2968032 2968150 119 -      
ENSG00000101577 E035 0.0000000       18 2972360 2972392 33 -      
ENSG00000101577 E036 0.0000000       18 2977083 2977185 103 -      
ENSG00000101577 E037 0.0000000       18 2982668 2982873 206 -      
ENSG00000101577 E038 0.0000000       18 2986045 2986130 86 -      
ENSG00000101577 E039 0.3560444 0.0322765936 1.476612e-01   18 3011718 3011959 242 - 0.211 0.000 -12.384
ENSG00000101577 E040 0.0000000       18 3013037 3013086 50 -      
ENSG00000101577 E041 1.7248365 0.0075543991 3.780284e-01 6.651632e-01 18 3013087 3013271 185 - 0.352 0.518 0.877

Help

Please Click HERE to learn more details about the results from DEXseq.