ENSG00000101997

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376227 ENSG00000101997 No_inf pgKDN_inf CCDC22 protein_coding protein_coding 10.18791 8.751822 10.49091 0.1223898 0.8694627 0.2612109 9.8717313 8.102714 10.49091 0.4202151 0.8694627 0.3722572 0.96559167 0.92445 1 0.07555 0.03305893 0.03305893 FALSE  
MSTRG.29970.3 ENSG00000101997 No_inf pgKDN_inf CCDC22 protein_coding   10.18791 8.751822 10.49091 0.1223898 0.8694627 0.2612109 0.3161824 0.649108 0.00000 0.3074060 0.0000000 -6.0424430 0.03440833 0.07555 0 -0.07555 0.15004242 0.03305893 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000101997 E001 0.6086152 0.014790817 0.69022592 0.87279951 X 49235470 49235495 26 + 0.235 0.176 -0.524
ENSG00000101997 E002 7.2179991 0.014718458 0.99644840 1.00000000 X 49235496 49235686 191 + 0.913 0.916 0.012
ENSG00000101997 E003 0.2537694 0.016469788 0.23032666   X 49236893 49237085 193 + 0.000 0.176 10.465
ENSG00000101997 E004 9.4277013 0.024317288 0.92187519 0.97574057 X 49237086 49237263 178 + 1.025 1.011 -0.052
ENSG00000101997 E005 4.6551611 0.003701980 0.89425635 0.96500387 X 49242016 49242065 50 + 0.745 0.760 0.061
ENSG00000101997 E006 6.8302578 0.002419786 0.35914052 0.64855972 X 49242066 49242148 83 + 0.938 0.845 -0.354
ENSG00000101997 E007 8.5349533 0.001719334 0.30238198 0.59546771 X 49242886 49242992 107 + 1.025 0.929 -0.354
ENSG00000101997 E008 6.6214640 0.002160009 0.66717360 0.86152588 X 49243118 49243184 67 + 0.859 0.903 0.168
ENSG00000101997 E009 10.5285887 0.001468196 0.98578850 0.99910771 X 49243284 49243462 179 + 1.062 1.061 -0.006
ENSG00000101997 E010 0.2362687 0.015559877 0.25592232   X 49243463 49243466 4 + 0.170 0.000 -10.449
ENSG00000101997 E011 11.8625879 0.001235995 0.91896883 0.97453086 X 49246731 49246925 195 + 1.113 1.106 -0.028
ENSG00000101997 E012 5.9933809 0.040132529 0.95639810 0.98965422 X 49247496 49247558 63 + 0.844 0.845 0.003
ENSG00000101997 E013 8.1423101 0.002087956 0.09141742 0.31401497 X 49247649 49247768 120 + 1.034 0.875 -0.596
ENSG00000101997 E014 2.6766495 0.005615926 0.45246873 0.72567957 X 49248191 49248194 4 + 0.614 0.512 -0.469
ENSG00000101997 E015 8.0668146 0.001837483 0.74445162 0.89879857 X 49248195 49248310 116 + 0.973 0.942 -0.114
ENSG00000101997 E016 8.7811421 0.001933078 0.43753196 0.71381013 X 49248407 49248523 117 + 1.025 0.954 -0.261
ENSG00000101997 E017 10.3631882 0.001661492 0.02848979 0.15808512 X 49248633 49248734 102 + 0.950 1.138 0.689
ENSG00000101997 E018 13.8349105 0.001090911 0.00567268 0.05421767 X 49248817 49248924 108 + 1.053 1.261 0.743
ENSG00000101997 E019 11.2721915 0.001266162 0.83491497 0.94057112 X 49249167 49249262 96 + 1.080 1.097 0.061
ENSG00000101997 E020 8.3092862 0.002857635 0.58177127 0.81374651 X 49249509 49249568 60 + 0.994 0.942 -0.194
ENSG00000101997 E021 9.4315466 0.012549517 0.91642054 0.97370772 X 49249651 49249725 75 + 1.015 1.021 0.024
ENSG00000101997 E022 14.9137945 0.000983140 0.61309376 0.83181039 X 49250148 49250520 373 + 1.219 1.183 -0.128

Help

Please Click HERE to learn more details about the results from DEXseq.