ENSG00000102030

Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370009 ENSG00000102030 No_inf pgKDN_inf NAA10 protein_coding protein_coding 82.76068 61.81377 99.2538 1.587522 2.988455 0.6831061 36.436652 23.637316 48.241373 1.2084361 3.238954 1.0288936 0.43296667 0.381750 0.485575 0.103825 0.31480900 0.01452827 FALSE  
ENST00000393712 ENSG00000102030 No_inf pgKDN_inf NAA10 protein_coding protein_coding 82.76068 61.81377 99.2538 1.587522 2.988455 0.6831061 11.668997 4.509014 22.656788 2.6648966 3.237203 2.3265000 0.12851667 0.072275 0.226800 0.154525 0.27685264 0.01452827 FALSE  
ENST00000460996 ENSG00000102030 No_inf pgKDN_inf NAA10 protein_coding retained_intron 82.76068 61.81377 99.2538 1.587522 2.988455 0.6831061 14.219647 10.151768 13.732819 0.5160188 2.756278 0.4355266 0.17287500 0.164325 0.137300 -0.027025 0.83428937 0.01452827 FALSE  
ENST00000466877 ENSG00000102030 No_inf pgKDN_inf NAA10 protein_coding retained_intron 82.76068 61.81377 99.2538 1.587522 2.988455 0.6831061 1.721799 3.350827 0.000000 1.3931588 0.000000 -8.3926726 0.02464167 0.053550 0.000000 -0.053550 0.01452827 0.01452827 TRUE  
ENST00000484950 ENSG00000102030 No_inf pgKDN_inf NAA10 protein_coding retained_intron 82.76068 61.81377 99.2538 1.587522 2.988455 0.6831061 4.212806 4.485808 2.325951 0.6524596 1.045954 -0.9445702 0.05443333 0.072750 0.024325 -0.048425 0.36590291 0.01452827 FALSE  
ENST00000700299 ENSG00000102030 No_inf pgKDN_inf NAA10 protein_coding retained_intron 82.76068 61.81377 99.2538 1.587522 2.988455 0.6831061 2.106463 4.174687 1.041178 1.4127558 0.638163 -1.9931130 0.03040000 0.067800 0.010850 -0.056950 0.48800836 0.01452827 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results from IsoformSwitchAnalyzeR.