ENSG00000102543

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000251108 ENSG00000102543 No_inf pgKDN_inf CDADC1 protein_coding protein_coding 2.919814 2.94998 3.274851 0.7450165 0.5338447 0.1502403 1.4682017 1.67475051 1.3661516 0.23072390 0.2472595 -0.29189558 0.5807083 0.675700 0.46695 -0.208750 0.80878562 0.03694442 FALSE TRUE
ENST00000466868 ENSG00000102543 No_inf pgKDN_inf CDADC1 protein_coding protein_coding_CDS_not_defined 2.919814 2.94998 3.274851 0.7450165 0.5338447 0.1502403 0.3674261 0.42393155 0.4151448 0.42393155 0.4151448 -0.02951335 0.1051333 0.101425 0.10420 0.002775 1.00000000 0.03694442 FALSE FALSE
ENST00000496061 ENSG00000102543 No_inf pgKDN_inf CDADC1 protein_coding nonsense_mediated_decay 2.919814 2.94998 3.274851 0.7450165 0.5338447 0.1502403 0.5623905 0.07205962 1.4935542 0.07205962 0.4876812 4.19556061 0.1673917 0.017250 0.42885 0.411600 0.03694442 0.03694442 TRUE TRUE
MSTRG.7824.2 ENSG00000102543 No_inf pgKDN_inf CDADC1 protein_coding   2.919814 2.94998 3.274851 0.7450165 0.5338447 0.1502403 0.3381639 0.68320617 0.0000000 0.68320617 0.0000000 -6.11521258 0.0854000 0.163575 0.00000 -0.163575 0.83546823 0.03694442 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000102543 E001 0.0000000       13 49247925 49247932 8 +      
ENSG00000102543 E002 0.1170040 0.011901129 0.498623727   13 49247933 49247935 3 + 0.097 0.000 -10.519
ENSG00000102543 E003 0.1170040 0.011901129 0.498623727   13 49247936 49247940 5 + 0.097 0.000 -12.763
ENSG00000102543 E004 0.1170040 0.011901129 0.498623727   13 49247941 49247946 6 + 0.097 0.000 -12.763
ENSG00000102543 E005 0.8521940 0.014443710 0.622437737 0.83732729 13 49247947 49247976 30 + 0.302 0.234 -0.490
ENSG00000102543 E006 1.8471320 0.198536539 0.673865201 0.86494151 13 49247977 49248047 71 + 0.399 0.498 0.511
ENSG00000102543 E007 2.2462905 0.006918540 0.022959339 0.13820190 13 49248048 49248119 72 + 0.302 0.637 1.732
ENSG00000102543 E008 0.1272623 0.013067214 0.583843871   13 49248120 49248469 350 + 0.000 0.093 11.734
ENSG00000102543 E009 1.8596556 0.056542565 0.284173808 0.57792723 13 49248871 49248965 95 + 0.353 0.530 0.925
ENSG00000102543 E010 1.3525515 0.179919862 0.992731067 1.00000000 13 49255839 49255913 75 + 0.353 0.386 0.187
ENSG00000102543 E011 0.0000000       13 49255914 49255915 2 +      
ENSG00000102543 E012 3.3542570 0.017590308 0.001043076 0.01548081 13 49259346 49259485 140 + 0.815 0.386 -1.949
ENSG00000102543 E013 2.7846916 0.005901969 0.087069018 0.30578761 13 49259486 49259523 38 + 0.678 0.464 -0.982
ENSG00000102543 E014 0.6069811 0.014918463 0.586339673 0.81656357 13 49265879 49265984 106 + 0.244 0.169 -0.660
ENSG00000102543 E015 0.3549719 0.017780118 0.088928786   13 49265985 49266003 19 + 0.244 0.000 -13.994
ENSG00000102543 E016 7.5388952 0.002680103 0.042835141 0.20173511 13 49267490 49268059 570 + 1.013 0.843 -0.641
ENSG00000102543 E017 0.8900499 0.019672940 0.006289834 0.05839450 13 49274291 49274331 41 + 0.000 0.426 13.990
ENSG00000102543 E018 0.7624406 0.014138688 0.012650295 0.09357162 13 49274332 49274340 9 + 0.000 0.386 13.829
ENSG00000102543 E019 2.7473085 0.005423252 0.013662143 0.09844409 13 49278350 49278519 170 + 0.353 0.704 1.691
ENSG00000102543 E020 2.0743652 0.086197567 0.741496229 0.89751136 13 49280509 49280698 190 + 0.513 0.464 -0.244
ENSG00000102543 E021 0.9503153 0.013564010 0.019524972 0.12505874 13 49286222 49286282 61 + 0.441 0.093 -2.882
ENSG00000102543 E022 14.1708115 0.002010041 0.076873419 0.28351278 13 49291684 49293485 1802 + 1.107 1.236 0.458

Help

Please Click HERE to learn more details about the results from DEXseq.