ENSG00000103024

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219302 ENSG00000103024 No_inf pgKDN_inf NME3 protein_coding protein_coding 54.22935 58.75848 52.96387 4.419976 2.158099 -0.1497618 27.866346 26.462024 29.285159 4.765494 0.9956330 0.1461938 0.51855833 0.449725 0.554000 0.104275 6.403539e-01 2.690815e-05 FALSE  
ENST00000563498 ENSG00000103024 No_inf pgKDN_inf NME3 protein_coding protein_coding 54.22935 58.75848 52.96387 4.419976 2.158099 -0.1497618 10.690214 12.687724 11.175977 2.130404 0.8798093 -0.1828787 0.19567500 0.215975 0.213450 -0.002525 1.000000e+00 2.690815e-05    
ENST00000564628 ENSG00000103024 No_inf pgKDN_inf NME3 protein_coding protein_coding 54.22935 58.75848 52.96387 4.419976 2.158099 -0.1497618 1.288278 0.000000 2.973106 0.000000 0.7685175 8.2206713 0.02401667 0.000000 0.055475 0.055475 2.690815e-05 2.690815e-05 FALSE  
ENST00000567271 ENSG00000103024 No_inf pgKDN_inf NME3 protein_coding retained_intron 54.22935 58.75848 52.96387 4.419976 2.158099 -0.1497618 9.009178 14.327075 6.221598 1.627266 2.5091179 -1.2020766 0.16196667 0.246600 0.115475 -0.131125 5.258656e-01 2.690815e-05    
MSTRG.10421.7 ENSG00000103024 No_inf pgKDN_inf NME3 protein_coding   54.22935 58.75848 52.96387 4.419976 2.158099 -0.1497618 3.517454 4.796858 2.156723 2.224860 0.8790416 -1.1495796 0.06285833 0.080300 0.039300 -0.041000 8.417261e-01 2.690815e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103024 E001 0.0000000       16 1770320 1770334 15 -      
ENSG00000103024 E002 0.0000000       16 1770335 1770340 6 -      
ENSG00000103024 E003 0.0000000       16 1770341 1770341 1 -      
ENSG00000103024 E004 0.0000000       16 1770342 1770343 2 -      
ENSG00000103024 E005 4.5055222 0.0058057956 0.166386916 0.43660173 16 1770344 1770376 33 - 0.823 0.659 -0.666
ENSG00000103024 E006 21.5823489 0.0086104366 0.306556262 0.59976804 16 1770377 1770460 84 - 1.388 1.318 -0.241
ENSG00000103024 E007 14.8395126 0.0249675890 0.404707234 0.68741953 16 1770461 1770480 20 - 1.234 1.164 -0.250
ENSG00000103024 E008 26.2794702 0.0077840904 0.575941482 0.81027827 16 1770481 1770541 61 - 1.450 1.418 -0.112
ENSG00000103024 E009 41.1430975 0.0003794921 0.256747034 0.54886815 16 1770542 1770648 107 - 1.591 1.643 0.179
ENSG00000103024 E010 57.5221993 0.0038833033 0.248328195 0.53922751 16 1770649 1770766 118 - 1.735 1.784 0.168
ENSG00000103024 E011 0.2444846 0.0164642991 0.880573811   16 1770767 1770880 114 - 0.104 0.087 -0.274
ENSG00000103024 E012 24.4257919 0.0005895077 0.551723736 0.79550521 16 1770881 1770888 8 - 1.420 1.387 -0.115
ENSG00000103024 E013 52.2929564 0.0002781365 0.373355975 0.66109843 16 1770889 1770993 105 - 1.741 1.708 -0.111
ENSG00000103024 E014 4.6639779 0.0030973095 0.787162394 0.91827951 16 1770994 1771069 76 - 0.767 0.737 -0.122
ENSG00000103024 E015 43.0014379 0.0003498062 0.741632466 0.89760795 16 1771070 1771171 102 - 1.647 1.634 -0.043
ENSG00000103024 E016 7.1286299 0.0312508628 0.001066181 0.01573711 16 1771172 1771191 20 - 0.626 1.042 1.633
ENSG00000103024 E017 5.6306617 0.0452653207 0.003189404 0.03613721 16 1771192 1771268 77 - 0.534 0.955 1.726
ENSG00000103024 E018 1.1986677 0.0101523844 0.025277174 0.14630812 16 1771269 1771279 11 - 0.499 0.160 -2.274
ENSG00000103024 E019 21.9991623 0.0006549923 0.857115493 0.94993562 16 1771280 1771304 25 - 1.363 1.354 -0.032
ENSG00000103024 E020 27.1767281 0.0006266705 0.801637462 0.92598357 16 1771305 1771410 106 - 1.437 1.453 0.054
ENSG00000103024 E021 3.0672832 0.0048731910 0.780302739 0.91526604 16 1771411 1771488 78 - 0.626 0.590 -0.159
ENSG00000103024 E022 12.1074835 0.0120836910 0.264242675 0.55727731 16 1771489 1771561 73 - 1.168 1.068 -0.362

Help

Please Click HERE to learn more details about the results from DEXseq.