ENSG00000103035

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219313 ENSG00000103035 No_inf pgKDN_inf PSMD7 protein_coding protein_coding 64.06532 47.15338 70.53479 0.9444989 2.079089 0.5808723 58.65316 39.99644 67.16606 0.8579762 1.379897 0.7477149 0.9088167 0.84965 0.95315 0.1035 0.01327121 0.01327121 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103035 E001 1.195958 0.0116277480 0.210955431 0.49578065 16 74296814 74296814 1 + 0.406 0.210 -1.316
ENSG00000103035 E002 1.449602 0.0163039613 0.711308987 0.88333927 16 74296815 74296819 5 + 0.406 0.350 -0.316
ENSG00000103035 E003 1.449602 0.0163039613 0.711308987 0.88333927 16 74296820 74296820 1 + 0.406 0.350 -0.316
ENSG00000103035 E004 3.145674 0.0047961921 0.679519364 0.86760121 16 74296821 74296828 8 + 0.632 0.579 -0.233
ENSG00000103035 E005 32.965959 0.0004797531 0.302822067 0.59594616 16 74296829 74296988 160 + 1.541 1.493 -0.167
ENSG00000103035 E006 1.134096 0.0107580668 0.001814428 0.02368903 16 74299576 74299745 170 + 0.077 0.542 3.684
ENSG00000103035 E007 35.597688 0.0100773707 0.989004100 1.00000000 16 74300115 74300206 92 + 1.553 1.557 0.012
ENSG00000103035 E008 1.239957 0.0234133269 0.049798332 0.22016749 16 74300207 74300477 271 + 0.198 0.501 1.907
ENSG00000103035 E009 38.774640 0.0004426343 0.708338816 0.88176951 16 74301052 74301144 93 + 1.583 1.603 0.069
ENSG00000103035 E010 49.822982 0.0004025716 0.251415692 0.54257807 16 74301555 74301652 98 + 1.714 1.671 -0.145
ENSG00000103035 E011 44.559604 0.0004216225 0.066780650 0.26040121 16 74302212 74302292 81 + 1.679 1.603 -0.257
ENSG00000103035 E012 1.989177 0.1265923651 0.039282687 0.19195535 16 74303989 74304302 314 + 0.294 0.645 1.821
ENSG00000103035 E013 31.097102 0.0004988489 0.930975331 0.97985955 16 74304303 74304394 92 + 1.498 1.497 -0.005
ENSG00000103035 E014 3.435359 0.0049642471 0.111422385 0.35051459 16 74304395 74304709 315 + 0.545 0.752 0.891
ENSG00000103035 E015 0.000000       16 74305289 74305445 157 +      
ENSG00000103035 E016 31.369986 0.0033723976 0.019108193 0.12327527 16 74305446 74306288 843 + 1.445 1.575 0.448

Help

Please Click HERE to learn more details about the results from DEXseq.