ENSG00000103066

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219345 ENSG00000103066 No_inf pgKDN_inf PLA2G15 protein_coding protein_coding 52.09074 63.89816 47.91178 1.904676 0.7567748 -0.4153188 19.481687 14.038586 24.4787915 2.4047538 1.8317137 0.8016967 0.39510000 0.222675 0.511375 0.288700 0.005975676 0.005975676 FALSE TRUE
ENST00000413021 ENSG00000103066 No_inf pgKDN_inf PLA2G15 protein_coding protein_coding 52.09074 63.89816 47.91178 1.904676 0.7567748 -0.4153188 3.090241 1.946369 3.2998379 1.2048514 1.0773398 0.7585823 0.06320000 0.030850 0.068375 0.037525 0.615668776 0.005975676 FALSE TRUE
ENST00000444212 ENSG00000103066 No_inf pgKDN_inf PLA2G15 protein_coding protein_coding 52.09074 63.89816 47.91178 1.904676 0.7567748 -0.4153188 15.736127 23.495095 10.0063518 3.3668611 3.4347743 -1.2306164 0.29453333 0.371625 0.206625 -0.165000 0.668607073 0.005975676 FALSE TRUE
ENST00000562449 ENSG00000103066 No_inf pgKDN_inf PLA2G15 protein_coding retained_intron 52.09074 63.89816 47.91178 1.904676 0.7567748 -0.4153188 2.209834 5.010408 0.8323809 0.2268467 0.3193723 -2.5752599 0.03799167 0.078850 0.017100 -0.061750 0.098011587 0.005975676 FALSE TRUE
MSTRG.11364.15 ENSG00000103066 No_inf pgKDN_inf PLA2G15 protein_coding   52.09074 63.89816 47.91178 1.904676 0.7567748 -0.4153188 3.505349 5.950015 3.9759146 4.8014454 3.9759146 -0.5804053 0.06241667 0.087800 0.085975 -0.001825 0.862731504 0.005975676 FALSE TRUE
MSTRG.11364.8 ENSG00000103066 No_inf pgKDN_inf PLA2G15 protein_coding   52.09074 63.89816 47.91178 1.904676 0.7567748 -0.4153188 3.601291 6.244270 2.4991098 0.3020301 0.7735338 -1.3176659 0.06615000 0.098400 0.052750 -0.045650 0.518968404 0.005975676 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103066 E001 0.1271363 0.0123015853 7.018938e-01   16 68245304 68245340 37 + 0.000 0.084 8.733
ENSG00000103066 E002 0.7446930 0.2196019944 6.520869e-01 8.534423e-01 16 68245341 68245370 30 + 0.193 0.269 0.621
ENSG00000103066 E003 0.7446930 0.2196019944 6.520869e-01 8.534423e-01 16 68245371 68245372 2 + 0.193 0.269 0.621
ENSG00000103066 E004 0.7446930 0.2196019944 6.520869e-01 8.534423e-01 16 68245373 68245378 6 + 0.193 0.269 0.621
ENSG00000103066 E005 0.9984009 0.0281533172 2.902424e-01 5.838842e-01 16 68245379 68245379 1 + 0.193 0.359 1.207
ENSG00000103066 E006 1.5055313 0.0193801790 5.338050e-02 2.299724e-01 16 68245380 68245384 5 + 0.193 0.498 1.944
ENSG00000103066 E007 4.3232707 0.0047225136 4.621208e-01 7.326499e-01 16 68245385 68245391 7 + 0.665 0.758 0.381
ENSG00000103066 E008 21.6956082 0.0006686589 1.588378e-01 4.259313e-01 16 68245392 68245553 162 + 1.398 1.313 -0.297
ENSG00000103066 E009 0.3728195 0.0165903012 7.625711e-01   16 68248287 68248568 282 + 0.107 0.155 0.622
ENSG00000103066 E010 0.3795211 0.5848617914 4.074912e-01   16 68248569 68248692 124 + 0.000 0.216 11.042
ENSG00000103066 E011 29.5041830 0.0004797840 4.866576e-05 1.300959e-03 16 68249290 68249446 157 + 1.590 1.376 -0.738
ENSG00000103066 E012 4.7416814 0.0029799728 1.220892e-02 9.153130e-02 16 68253422 68253517 96 + 0.545 0.859 1.310
ENSG00000103066 E013 7.6944648 0.0019041697 9.834185e-09 7.015833e-07 16 68254353 68254780 428 + 0.427 1.108 2.818
ENSG00000103066 E014 3.5211176 0.0290284175 2.138026e-03 2.685909e-02 16 68254781 68254918 138 + 0.326 0.789 2.207
ENSG00000103066 E015 12.2489177 0.0012550841 1.834924e-01 4.603869e-01 16 68254919 68254942 24 + 1.175 1.069 -0.378
ENSG00000103066 E016 23.0277068 0.0006297109 8.973480e-02 3.112381e-01 16 68254943 68255037 95 + 1.431 1.330 -0.347
ENSG00000103066 E017 1.7600237 0.0078230850 2.039711e-02 1.284861e-01 16 68255038 68255281 244 + 0.193 0.553 2.207
ENSG00000103066 E018 24.9375609 0.0010918320 4.813675e-01 7.464410e-01 16 68255282 68255380 99 + 1.431 1.391 -0.136
ENSG00000103066 E019 3.5136251 0.0258451719 8.066805e-03 6.950019e-02 16 68255381 68255705 325 + 0.379 0.774 1.824
ENSG00000103066 E020 1.3629697 0.0096458139 6.419510e-01 8.481245e-01 16 68255706 68255765 60 + 0.326 0.398 0.429
ENSG00000103066 E021 23.8622142 0.0095788152 7.926457e-01 9.208718e-01 16 68255766 68255890 125 + 1.398 1.384 -0.049
ENSG00000103066 E022 25.8667784 0.0007990755 8.164727e-02 2.938452e-01 16 68255891 68255990 100 + 1.477 1.380 -0.337
ENSG00000103066 E023 0.7445664 0.0268001382 6.231302e-01 8.377472e-01 16 68258139 68258233 95 + 0.193 0.269 0.622
ENSG00000103066 E024 414.4610202 0.0001182900 2.559661e-01 5.480024e-01 16 68259146 68261058 1913 + 2.605 2.618 0.041

Help

Please Click HERE to learn more details about the results from DEXseq.