ENSG00000103257

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261622 ENSG00000103257 No_inf pgKDN_inf SLC7A5 protein_coding protein_coding 83.12202 18.88518 84.49028 0.3696389 1.107611 2.160937 48.27419 6.671802 53.90631 0.8099470 3.008150 3.012413 0.5227667 0.353625 0.637225 0.2836 0.001933261 0.001933261 FALSE TRUE
ENST00000565644 ENSG00000103257 No_inf pgKDN_inf SLC7A5 protein_coding protein_coding 83.12202 18.88518 84.49028 0.3696389 1.107611 2.160937 34.84783 12.213382 30.58396 0.8884605 2.241639 1.323603 0.4772333 0.646375 0.362775 -0.2836 0.004387840 0.001933261 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103257 E001 720.116872 0.0015012790 4.649585e-03 4.699601e-02 16 87830023 87832731 2709 - 2.755 2.796 0.135
ENSG00000103257 E002 76.099045 0.0003739955 3.142420e-01 6.073581e-01 16 87832732 87833025 294 - 1.800 1.769 -0.105
ENSG00000103257 E003 45.626512 0.0003226787 9.202674e-01 9.752146e-01 16 87834414 87834591 178 - 1.575 1.582 0.022
ENSG00000103257 E004 7.511701 0.0046123450 2.755483e-01 5.691550e-01 16 87836498 87836647 150 - 0.872 0.742 -0.511
ENSG00000103257 E005 0.000000       16 87836648 87836805 158 -      
ENSG00000103257 E006 29.994373 0.0004779423 2.371536e-01 5.261381e-01 16 87837845 87837941 97 - 1.414 1.344 -0.241
ENSG00000103257 E007 43.541896 0.0003818235 3.858427e-01 6.716816e-01 16 87838714 87838817 104 - 1.564 1.527 -0.127
ENSG00000103257 E008 42.922154 0.0003474215 6.168940e-01 8.340721e-01 16 87839702 87839825 124 - 1.542 1.582 0.134
ENSG00000103257 E009 27.580536 0.0005243822 6.356505e-01 8.445486e-01 16 87840429 87840473 45 - 1.356 1.400 0.152
ENSG00000103257 E010 36.709521 0.0044197249 5.080556e-01 7.664318e-01 16 87841050 87841155 106 - 1.473 1.527 0.184
ENSG00000103257 E011 28.319057 0.0053089801 1.875447e-01 4.656619e-01 16 87851724 87851849 126 - 1.393 1.303 -0.314
ENSG00000103257 E012 0.000000       16 87863590 87863639 50 -      
ENSG00000103257 E013 58.953371 0.0006852786 2.387391e-06 9.866786e-05 16 87868885 87869507 623 - 1.725 1.479 -0.839

Help

Please Click HERE to learn more details about the results from DEXseq.