ENSG00000103335

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301015 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding protein_coding 162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 21.82573 28.23288 22.283287 0.9135849 1.1426113 -0.3412778 0.14443333 0.111900 0.181600 0.069700 2.231200e-01 1.476023e-11 FALSE TRUE
ENST00000419505 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding nonsense_mediated_decay 162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 25.20172 27.82365 24.811676 3.8276879 4.0521339 -0.1652295 0.17735833 0.109950 0.208500 0.098550 4.162660e-01 1.476023e-11 FALSE TRUE
ENST00000472168 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding retained_intron 162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 13.12854 18.88658 13.631258 1.8350481 4.8609485 -0.4701484 0.07833333 0.075025 0.101050 0.026025 1.000000e+00 1.476023e-11 FALSE FALSE
ENST00000484567 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding retained_intron 162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 28.20128 64.77995 8.776804 1.7958018 0.5492478 -2.8823596 0.14381667 0.256925 0.071125 -0.185800 1.476023e-11 1.476023e-11 FALSE TRUE
ENST00000518793 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding protein_coding 162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 17.76568 25.18394 13.952199 3.2772111 8.4491864 -0.8515507 0.10432500 0.099400 0.095650 -0.003750 8.032953e-01 1.476023e-11 FALSE TRUE
MSTRG.11733.4 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding   162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 12.44943 18.45789 7.826723 1.7317268 1.1189471 -1.2366965 0.07936667 0.073250 0.063925 -0.009325 8.591804e-01 1.476023e-11 TRUE TRUE
MSTRG.11733.9 ENSG00000103335 No_inf pgKDN_inf PIEZO1 protein_coding   162.912 252.3749 126.4726 3.432684 11.64869 -0.9966872 24.26074 34.17509 21.276858 2.0772391 1.6721858 -0.6834042 0.15480000 0.135350 0.169325 0.033975 6.219520e-01 1.476023e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103335 E001 0.0000000       16 88715338 88715342 5 -      
ENSG00000103335 E002 0.0000000       16 88715343 88715345 3 -      
ENSG00000103335 E003 35.9071313 0.0007098780 6.247969e-01 8.385803e-01 16 88715346 88715448 103 - 1.510 1.538 0.096
ENSG00000103335 E004 65.2265826 0.0002285443 5.630590e-01 8.026066e-01 16 88715449 88715490 42 - 1.766 1.791 0.084
ENSG00000103335 E005 293.7024474 0.0012435700 3.111850e-01 6.044090e-01 16 88715491 88715815 325 - 2.414 2.439 0.084
ENSG00000103335 E006 82.8503837 0.0001874838 5.154991e-01 7.715106e-01 16 88715816 88715854 39 - 1.901 1.879 -0.073
ENSG00000103335 E007 78.3466507 0.0032045508 8.087574e-01 9.294107e-01 16 88715933 88715970 38 - 1.853 1.866 0.042
ENSG00000103335 E008 54.3533200 0.0002790913 9.015197e-01 9.682877e-01 16 88715971 88715977 7 - 1.709 1.705 -0.014
ENSG00000103335 E009 147.6342823 0.0001380328 6.590872e-01 8.576338e-01 16 88715978 88716096 119 - 2.125 2.138 0.044
ENSG00000103335 E010 72.7936779 0.0011293769 5.929896e-01 8.205635e-01 16 88716097 88716119 23 - 1.844 1.825 -0.067
ENSG00000103335 E011 2.0137254 0.0069915009 7.904823e-02 2.883322e-01 16 88716120 88716197 78 - 0.236 0.522 1.688
ENSG00000103335 E012 123.9086284 0.0001492443 4.259911e-01 7.048154e-01 16 88716198 88716277 80 - 2.074 2.052 -0.073
ENSG00000103335 E013 161.7496187 0.0013706054 5.064197e-01 7.651421e-01 16 88716361 88716483 123 - 2.186 2.168 -0.060
ENSG00000103335 E014 214.4510597 0.0007629168 9.495736e-01 9.868879e-01 16 88716559 88716731 173 - 2.296 2.296 -0.001
ENSG00000103335 E015 3.2728505 0.0044246206 1.789025e-02 1.178567e-01 16 88716732 88716792 61 - 0.319 0.683 1.820
ENSG00000103335 E016 165.9859607 0.0001172929 4.255786e-02 2.010535e-01 16 88716806 88716898 93 - 2.147 2.200 0.179
ENSG00000103335 E017 216.3778367 0.0005517025 4.374000e-03 4.518431e-02 16 88717023 88717211 189 - 2.249 2.319 0.235
ENSG00000103335 E018 87.4040139 0.0004761497 6.584667e-35 4.864897e-32 16 88717212 88717536 325 - 1.464 2.014 1.862
ENSG00000103335 E019 33.0466507 0.0009676411 4.116014e-10 3.781824e-08 16 88717537 88717615 79 - 1.168 1.584 1.447
ENSG00000103335 E020 32.4564678 0.0020375880 6.442170e-12 7.553304e-10 16 88717616 88717714 99 - 1.098 1.586 1.701
ENSG00000103335 E021 27.5841621 0.0005346391 2.847215e-13 3.968002e-11 16 88717715 88717808 94 - 0.968 1.526 1.972
ENSG00000103335 E022 124.8941973 0.0015732153 2.226790e-48 3.245938e-45 16 88717809 88718741 933 - 1.560 2.174 2.069
ENSG00000103335 E023 0.0000000       16 88718972 88719573 602 -      
ENSG00000103335 E024 0.0000000       16 88719574 88719721 148 -      
ENSG00000103335 E025 0.0000000       16 88719802 88719960 159 -      
ENSG00000103335 E026 0.0000000       16 88720069 88720283 215 -      
ENSG00000103335 E027 0.0000000       16 88720284 88720384 101 -      
ENSG00000103335 E028 40.5222907 0.0026655368 1.884406e-02 1.220682e-01 16 88720385 88720532 148 - 1.664 1.541 -0.419
ENSG00000103335 E029 70.5553225 0.0016686673 5.215399e-05 1.380213e-03 16 88720616 88720659 44 - 1.924 1.762 -0.546
ENSG00000103335 E030 83.5567265 0.0042516721 8.930985e-02 3.102461e-01 16 88720660 88720745 86 - 1.939 1.867 -0.242
ENSG00000103335 E031 32.2610770 0.0004189179 9.235552e-02 3.156159e-01 16 88720746 88720748 3 - 1.413 1.513 0.342
ENSG00000103335 E032 120.0139900 0.0001487272 2.863190e-01 5.799717e-01 16 88721166 88721430 265 - 2.066 2.036 -0.101
ENSG00000103335 E033 84.0303663 0.0015349382 1.936035e-02 1.243369e-01 16 88721538 88721673 136 - 1.951 1.864 -0.294
ENSG00000103335 E034 45.0187717 0.0003556800 3.144515e-02 1.673537e-01 16 88721674 88721726 53 - 1.693 1.593 -0.340
ENSG00000103335 E035 118.0480476 0.0001505184 8.101266e-02 2.924540e-01 16 88721808 88722066 259 - 2.073 2.022 -0.169
ENSG00000103335 E036 43.8517462 0.0003181640 2.769557e-01 5.703882e-01 16 88722218 88722303 86 - 1.650 1.599 -0.174
ENSG00000103335 E037 50.8586665 0.0055777590 5.990592e-01 8.242042e-01 16 88722304 88722397 94 - 1.696 1.669 -0.092
ENSG00000103335 E038 0.3720642 0.0165850517 9.795460e-01   16 88722523 88722582 60 - 0.134 0.125 -0.119
ENSG00000103335 E039 59.0299371 0.0009242531 5.392613e-01 7.877143e-01 16 88722583 88722689 107 - 1.721 1.749 0.096
ENSG00000103335 E040 33.7907251 0.0004677909 1.221180e-01 3.695715e-01 16 88722837 88722872 36 - 1.561 1.478 -0.282
ENSG00000103335 E041 56.6409903 0.0003653349 1.446797e-02 1.025517e-01 16 88722873 88722981 109 - 1.792 1.690 -0.345
ENSG00000103335 E042 23.6700394 0.0006145113 8.081545e-03 6.957730e-02 16 88722982 88723009 28 - 1.464 1.300 -0.571
ENSG00000103335 E043 30.6458428 0.0050368105 9.433186e-02 3.196792e-01 16 88723095 88723151 57 - 1.534 1.430 -0.357
ENSG00000103335 E044 39.5157334 0.0003986615 1.232164e-02 9.192906e-02 16 88723226 88723316 91 - 1.653 1.530 -0.420
ENSG00000103335 E045 17.7917852 0.0007409976 1.277836e-01 3.789974e-01 16 88723317 88723328 12 - 1.311 1.203 -0.382
ENSG00000103335 E046 31.7029334 0.0005317219 3.310297e-01 6.233201e-01 16 88723871 88723946 76 - 1.437 1.495 0.199
ENSG00000103335 E047 19.2122273 0.0036429251 5.343211e-02 2.301028e-01 16 88723947 88723971 25 - 1.157 1.310 0.542
ENSG00000103335 E048 22.1300125 0.0050264215 5.543247e-01 7.971032e-01 16 88725009 88725080 72 - 1.296 1.341 0.158
ENSG00000103335 E049 38.6936068 0.0056742547 4.700732e-02 2.129818e-01 16 88725416 88725519 104 - 1.639 1.524 -0.394
ENSG00000103335 E050 41.9123674 0.0003306545 5.883925e-01 8.173607e-01 16 88725595 88725684 90 - 1.613 1.588 -0.087
ENSG00000103335 E051 0.5071304 0.0157432306 2.155481e-01 5.013097e-01 16 88725685 88726025 341 - 0.000 0.221 11.709
ENSG00000103335 E052 65.6200020 0.0002354863 6.043986e-01 8.274383e-01 16 88726284 88726455 172 - 1.800 1.780 -0.065
ENSG00000103335 E053 0.1271363 0.0122907754 1.000000e+00   16 88726456 88726489 34 - 0.000 0.067 9.786
ENSG00000103335 E054 51.1317713 0.0015780189 1.363755e-01 3.928051e-01 16 88726547 88726643 97 - 1.727 1.658 -0.233
ENSG00000103335 E055 94.2566015 0.0001842101 1.299036e-01 3.823484e-01 16 88726715 88726958 244 - 1.975 1.926 -0.164
ENSG00000103335 E056 27.0938290 0.0005053755 1.938912e-01 4.737235e-01 16 88727039 88727054 16 - 1.464 1.388 -0.265
ENSG00000103335 E057 63.0319968 0.0002255359 1.346746e-01 3.901421e-01 16 88727055 88727192 138 - 1.809 1.751 -0.199
ENSG00000103335 E058 53.9630608 0.0003274924 7.117232e-02 2.703498e-01 16 88727557 88727661 105 - 1.755 1.678 -0.261
ENSG00000103335 E059 0.8805755 0.0240843464 3.103513e-01 6.035036e-01 16 88727662 88727843 182 - 0.134 0.300 1.466
ENSG00000103335 E060 76.8085138 0.0002340135 1.855904e-04 3.933058e-03 16 88731706 88731910 205 - 1.942 1.809 -0.448
ENSG00000103335 E061 45.4926261 0.0083171072 9.795962e-02 3.263793e-01 16 88732335 88732463 129 - 1.696 1.599 -0.331
ENSG00000103335 E062 29.6096119 0.0004563769 3.503099e-01 6.405569e-01 16 88732464 88732535 72 - 1.485 1.433 -0.182
ENSG00000103335 E063 39.2817090 0.0004733590 9.147356e-05 2.206411e-03 16 88732607 88732732 126 - 1.693 1.501 -0.654
ENSG00000103335 E064 8.2740968 0.0016568209 1.556484e-02 1.077907e-01 16 88732733 88732980 248 - 0.727 0.999 1.051
ENSG00000103335 E065 59.4755628 0.0077464733 6.855380e-02 2.643063e-01 16 88733278 88733454 177 - 1.809 1.713 -0.326
ENSG00000103335 E066 45.2570347 0.0015104692 4.642108e-02 2.114103e-01 16 88733588 88733745 158 - 1.693 1.597 -0.327
ENSG00000103335 E067 30.1343717 0.0083163391 8.664233e-02 3.050439e-01 16 88733906 88734054 149 - 1.534 1.419 -0.394
ENSG00000103335 E068 41.8799421 0.0003566147 3.757600e-01 6.631189e-01 16 88734356 88734538 183 - 1.625 1.582 -0.144
ENSG00000103335 E069 45.9116675 0.0003406637 7.729690e-01 9.125992e-01 16 88734650 88734798 149 - 1.643 1.630 -0.042
ENSG00000103335 E070 49.3578349 0.0003127304 5.067193e-02 2.225340e-01 16 88734875 88735053 179 - 1.724 1.637 -0.294
ENSG00000103335 E071 21.6272186 0.0009312102 1.158089e-01 3.588646e-01 16 88735135 88735246 112 - 1.388 1.285 -0.360
ENSG00000103335 E072 41.6053149 0.0032034149 2.757148e-01 5.692674e-01 16 88736148 88736408 261 - 1.632 1.574 -0.195
ENSG00000103335 E073 0.1272623 0.0122936827 1.000000e+00   16 88736409 88736465 57 - 0.000 0.067 9.786
ENSG00000103335 E074 10.9083546 0.0014008438 7.665562e-01 9.094066e-01 16 88736639 88736739 101 - 1.059 1.033 -0.094
ENSG00000103335 E075 0.0000000       16 88737559 88737646 88 -      
ENSG00000103335 E076 0.0000000       16 88737728 88737814 87 -      
ENSG00000103335 E077 0.0000000       16 88737934 88738105 172 -      
ENSG00000103335 E078 0.0000000       16 88738227 88738440 214 -      
ENSG00000103335 E079 0.0000000       16 88738568 88738736 169 -      
ENSG00000103335 E080 6.1788870 0.0763595730 4.319263e-01 7.094921e-01 16 88741478 88741616 139 - 0.895 0.789 -0.414
ENSG00000103335 E081 0.0000000       16 88742053 88742095 43 -      
ENSG00000103335 E082 4.7292794 0.0319071912 7.810639e-01 9.157207e-01 16 88742300 88742422 123 - 0.696 0.739 0.177
ENSG00000103335 E083 16.3281987 0.0345288377 4.603822e-01 7.318603e-01 16 88749384 88749479 96 - 1.263 1.175 -0.312
ENSG00000103335 E084 28.9721189 0.0049236063 6.946517e-03 6.275603e-02 16 88784901 88785220 320 - 1.552 1.382 -0.585
ENSG00000103335 E085 0.0000000       16 88791812 88791853 42 -      

Help

Please Click HERE to learn more details about the results from DEXseq.