ENSG00000103423

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262375 ENSG00000103423 No_inf pgKDN_inf DNAJA3 protein_coding protein_coding 33.40259 26.40728 35.53867 1.55676 0.7197936 0.4283134 8.359106 4.200037 10.7292848 1.8615050 1.7986677 1.3509931 0.23979167 0.155050 0.299950 0.144900 0.57104361 0.04813743 FALSE  
ENST00000355296 ENSG00000103423 No_inf pgKDN_inf DNAJA3 protein_coding protein_coding 33.40259 26.40728 35.53867 1.55676 0.7197936 0.4283134 16.228985 8.151187 18.8748686 3.2398839 3.0532717 1.2103798 0.47465000 0.322125 0.534400 0.212275 0.69019531 0.04813743 FALSE  
ENST00000431375 ENSG00000103423 No_inf pgKDN_inf DNAJA3 protein_coding protein_coding 33.40259 26.40728 35.53867 1.55676 0.7197936 0.4283134 2.817497 4.262610 3.2757196 1.7986975 1.8999777 -0.3789083 0.08981667 0.155575 0.090575 -0.065000 0.82006906 0.04813743 FALSE  
ENST00000573120 ENSG00000103423 No_inf pgKDN_inf DNAJA3 protein_coding retained_intron 33.40259 26.40728 35.53867 1.55676 0.7197936 0.4283134 1.639862 2.963585 0.4108812 0.8315943 0.4108812 -2.8207184 0.05339167 0.108200 0.011700 -0.096500 0.04813743 0.04813743    
ENST00000576180 ENSG00000103423 No_inf pgKDN_inf DNAJA3 protein_coding retained_intron 33.40259 26.40728 35.53867 1.55676 0.7197936 0.4283134 2.032604 2.717780 1.3093961 0.4684669 0.2823071 -1.0478497 0.06535833 0.104800 0.037275 -0.067525 0.32885028 0.04813743 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103423 E001 0.0000000       16 4425805 4425859 55 +      
ENSG00000103423 E002 0.1272623 0.0124222885 3.638713e-01   16 4425860 4425864 5 + 0.000 0.113 9.981
ENSG00000103423 E003 0.1272623 0.0124222885 3.638713e-01   16 4425865 4425867 3 + 0.000 0.113 12.096
ENSG00000103423 E004 2.1946437 0.0064215685 7.438490e-01 0.8986974699 16 4425868 4425878 11 + 0.480 0.528 0.231
ENSG00000103423 E005 13.0426041 0.0015739466 3.744275e-01 0.6620888017 16 4425879 4426047 169 + 1.111 1.183 0.256
ENSG00000103423 E006 8.4914606 0.0028451253 5.580979e-01 0.7997781674 16 4426048 4426092 45 + 0.995 0.940 -0.206
ENSG00000103423 E007 0.2536433 0.0160352938 1.375259e-01   16 4431599 4431672 74 + 0.000 0.202 13.034
ENSG00000103423 E008 0.0000000       16 4431673 4431868 196 +      
ENSG00000103423 E009 0.4982540 0.0152855058 1.699696e-01   16 4433846 4434102 257 + 0.080 0.276 2.138
ENSG00000103423 E010 0.9825072 0.0129367289 5.962047e-01 0.8224987943 16 4434298 4434383 86 + 0.257 0.340 0.553
ENSG00000103423 E011 17.1905273 0.0158592068 1.662666e-01 0.4364397323 16 4434384 4434517 134 + 1.301 1.183 -0.416
ENSG00000103423 E012 12.7320440 0.0072950120 3.937856e-01 0.6786732172 16 4437402 4437485 84 + 1.163 1.089 -0.265
ENSG00000103423 E013 1.6330105 0.0085571624 1.195464e-03 0.0171533043 16 4437486 4437625 140 + 0.147 0.630 3.013
ENSG00000103423 E014 5.6456369 0.0368420447 1.808271e-01 0.4565670467 16 4440257 4441374 1118 + 0.736 0.909 0.678
ENSG00000103423 E015 19.8461428 0.0006649281 8.560074e-02 0.3028002456 16 4441375 4441505 131 + 1.358 1.246 -0.394
ENSG00000103423 E016 13.5716166 0.0010302708 2.866176e-01 0.5801409325 16 4441506 4441575 70 + 1.192 1.109 -0.295
ENSG00000103423 E017 24.4648697 0.0005820132 7.313569e-01 0.8932539387 16 4442268 4442420 153 + 1.392 1.413 0.075
ENSG00000103423 E018 2.8400502 0.0048095776 5.304551e-02 0.2290450341 16 4442421 4443016 596 + 0.450 0.712 1.191
ENSG00000103423 E019 26.4593939 0.0031646990 6.491952e-01 0.8521634391 16 4443017 4443164 148 + 1.445 1.418 -0.092
ENSG00000103423 E020 18.2573727 0.0012011854 8.435551e-02 0.2999690048 16 4444664 4444728 65 + 1.326 1.207 -0.418
ENSG00000103423 E021 27.1801435 0.0006774714 4.082367e-01 0.6906257750 16 4446886 4447014 129 + 1.464 1.418 -0.156
ENSG00000103423 E022 0.8707568 0.0864135213 1.290427e-01 0.3811703607 16 4447015 4447955 941 + 0.147 0.395 1.875
ENSG00000103423 E023 26.6580668 0.0005383836 6.704284e-01 0.8630629152 16 4448733 4448848 116 + 1.426 1.451 0.088
ENSG00000103423 E024 7.0875356 0.0022422273 7.694325e-06 0.0002726582 16 4449554 4450399 846 + 0.647 1.109 1.788
ENSG00000103423 E025 24.8393587 0.0069785122 7.081592e-01 0.8816679952 16 4450400 4450497 98 + 1.395 1.423 0.097
ENSG00000103423 E026 9.3732749 0.0015518953 6.902743e-01 0.8728118365 16 4454811 4454927 117 + 0.995 1.033 0.138
ENSG00000103423 E027 0.2438580 0.0163040390 7.674742e-01   16 4455492 4455545 54 + 0.080 0.113 0.553
ENSG00000103423 E028 47.4182688 0.0003269023 1.375885e-01 0.3948650933 16 4455546 4455780 235 + 1.705 1.643 -0.209
ENSG00000103423 E029 124.8650594 0.0001913979 5.961468e-01 0.8224891697 16 4455781 4456487 707 + 2.089 2.103 0.048
ENSG00000103423 E030 30.2011221 0.0004694425 5.742645e-01 0.8093334340 16 4456488 4456775 288 + 1.476 1.507 0.108

Help

Please Click HERE to learn more details about the results from DEXseq.