ENSG00000103479

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262133 ENSG00000103479 No_inf pgKDN_inf RBL2 protein_coding protein_coding 26.50117 35.59178 21.89622 1.542577 0.8412063 -0.7006089 11.538763 9.057024 13.471687 2.1618555 1.2632723 0.5723001 0.4723333 0.248250 0.61740 0.369150 0.009651167 0.009651167 FALSE TRUE
ENST00000379935 ENSG00000103479 No_inf pgKDN_inf RBL2 protein_coding protein_coding_CDS_not_defined 26.50117 35.59178 21.89622 1.542577 0.8412063 -0.7006089 4.503107 9.487555 2.847496 3.3846225 2.2168250 -1.7328044 0.1498167 0.278300 0.12435 -0.153950 0.658995150 0.009651167 FALSE TRUE
ENST00000680543 ENSG00000103479 No_inf pgKDN_inf RBL2 protein_coding retained_intron 26.50117 35.59178 21.89622 1.542577 0.8412063 -0.7006089 3.578474 6.397721 2.060986 0.5361359 0.4048234 -1.6294935 0.1273000 0.182600 0.09505 -0.087550 0.484775024 0.009651167 TRUE TRUE
MSTRG.11178.4 ENSG00000103479 No_inf pgKDN_inf RBL2 protein_coding   26.50117 35.59178 21.89622 1.542577 0.8412063 -0.7006089 5.458484 8.197250 2.871337 2.4332114 1.2860310 -1.5101607 0.2026417 0.226125 0.13550 -0.090625 0.789115436 0.009651167 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103479 E001 0.0000000       16 53433977 53434276 300 +      
ENSG00000103479 E002 0.2459655 0.0162080566 6.765904e-01   16 53434418 53434470 53 + 0.121 0.074 -0.775
ENSG00000103479 E003 10.1986882 0.0013793974 1.002162e-01 3.307809e-01 16 53434471 53434796 326 + 1.119 0.974 -0.531
ENSG00000103479 E004 0.4999558 0.0156909706 6.416098e-01 8.478681e-01 16 53435619 53435744 126 + 0.121 0.194 0.810
ENSG00000103479 E005 12.4501414 0.0335943620 4.562885e-01 7.286943e-01 16 53439016 53439146 131 + 1.160 1.081 -0.285
ENSG00000103479 E006 18.0956096 0.0009484002 1.394397e-01 3.970718e-01 16 53442658 53442858 201 + 1.326 1.223 -0.360
ENSG00000103479 E007 0.2545247 0.2544651971 5.501144e-01   16 53445781 53445929 149 + 0.000 0.138 9.942
ENSG00000103479 E008 8.7192390 0.0118791567 1.288477e-01 3.807820e-01 16 53447042 53447106 65 + 1.063 0.909 -0.571
ENSG00000103479 E009 15.4998587 0.0014299172 1.235732e-01 3.722222e-01 16 53451703 53451831 129 + 1.270 1.155 -0.406
ENSG00000103479 E010 8.6404003 0.0385820683 8.529896e-01 9.481490e-01 16 53453452 53453474 23 + 0.984 0.956 -0.103
ENSG00000103479 E011 15.7084097 0.0008807134 2.140239e-02 1.324680e-01 16 53453475 53453612 138 + 1.306 1.137 -0.594
ENSG00000103479 E012 13.8269494 0.0026819848 2.330598e-03 2.862638e-02 16 53453705 53453769 65 + 1.292 1.053 -0.851
ENSG00000103479 E013 0.1186381 0.0117539577 3.060128e-01   16 53454226 53454347 122 + 0.121 0.000 -11.676
ENSG00000103479 E014 30.4887845 0.0063066218 2.479719e-02 1.447883e-01 16 53454656 53454842 187 + 1.563 1.425 -0.471
ENSG00000103479 E015 23.5930768 0.0006848386 7.076142e-01 8.813176e-01 16 53459451 53459617 167 + 1.387 1.363 -0.082
ENSG00000103479 E016 9.0167343 0.0018051294 8.001103e-01 9.251341e-01 16 53461741 53461768 28 + 0.998 0.974 -0.090
ENSG00000103479 E017 14.1095731 0.0018921728 1.846955e-02 1.202773e-01 16 53461769 53461850 82 + 1.270 1.087 -0.649
ENSG00000103479 E018 16.0847776 0.0011964102 2.473735e-02 1.445800e-01 16 53462552 53462655 104 + 1.312 1.149 -0.576
ENSG00000103479 E019 13.1956110 0.0011177361 3.714026e-01 6.593395e-01 16 53464226 53464290 65 + 1.179 1.107 -0.257
ENSG00000103479 E020 14.6039923 0.0010130655 9.164964e-01 9.737086e-01 16 53464291 53464363 73 + 1.169 1.177 0.028
ENSG00000103479 E021 1.0061699 0.0117715411 1.269293e-01 3.776387e-01 16 53464364 53464877 514 + 0.121 0.364 2.033
ENSG00000103479 E022 24.6482281 0.0052399534 2.729698e-01 5.667444e-01 16 53465438 53465602 165 + 1.435 1.363 -0.250
ENSG00000103479 E023 39.1333799 0.0003897984 7.873776e-10 6.905109e-08 16 53465603 53466773 1171 + 1.345 1.674 1.129
ENSG00000103479 E024 10.7324152 0.0015158821 1.386114e-02 9.934985e-02 16 53466774 53467057 284 + 0.888 1.119 0.855
ENSG00000103479 E025 20.1856948 0.0007004048 6.061402e-01 8.284945e-01 16 53467058 53467169 112 + 1.284 1.319 0.120
ENSG00000103479 E026 34.6928122 0.0004195026 5.096729e-01 7.674763e-01 16 53469916 53470185 270 + 1.555 1.521 -0.117
ENSG00000103479 E027 9.5144896 0.0051085460 1.649362e-03 2.201354e-02 16 53470186 53470382 197 + 0.764 1.094 1.249
ENSG00000103479 E028 45.1427954 0.0003435562 6.696195e-02 2.608173e-01 16 53470383 53470663 281 + 1.589 1.672 0.285
ENSG00000103479 E029 26.9686328 0.0005303872 8.357380e-01 9.410165e-01 16 53470746 53470922 177 + 1.420 1.432 0.040
ENSG00000103479 E030 0.0000000       16 53479154 53479225 72 +      
ENSG00000103479 E031 0.0000000       16 53479546 53479885 340 +      
ENSG00000103479 E032 0.0000000       16 53479886 53479991 106 +      
ENSG00000103479 E033 0.0000000       16 53480567 53480769 203 +      
ENSG00000103479 E034 32.9092940 0.0091432410 7.197170e-02 2.720579e-01 16 53481671 53481835 165 + 1.430 1.549 0.409
ENSG00000103479 E035 46.6613897 0.0003774050 5.724777e-01 8.084407e-01 16 53490130 53490301 172 + 1.642 1.667 0.084
ENSG00000103479 E036 48.5452268 0.0003981980 6.753463e-01 8.655111e-01 16 53490302 53490514 213 + 1.688 1.669 -0.063
ENSG00000103479 E037 105.1237013 0.0003637346 1.910849e-01 4.704466e-01 16 53490515 53491648 1134 + 1.981 2.019 0.127

Help

Please Click HERE to learn more details about the results from DEXseq.