ENSG00000103549

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000324685 ENSG00000103549 No_inf pgKDN_inf RNF40 protein_coding protein_coding 26.85609 22.35306 26.94216 0.9691217 0.5631954 0.2692833 17.830648 16.705328 15.002068 0.7668618 0.8476414 -0.1550489 0.67535000 0.752650 0.558375 -0.194275 0.26602024 0.01285284 FALSE TRUE
ENST00000567365 ENSG00000103549 No_inf pgKDN_inf RNF40 protein_coding protein_coding 26.85609 22.35306 26.94216 0.9691217 0.5631954 0.2692833 1.793278 2.217249 1.110898 1.2803048 1.1108984 -0.9906074 0.06453333 0.092400 0.038900 -0.053500 0.80030242 0.01285284 FALSE FALSE
MSTRG.11056.2 ENSG00000103549 No_inf pgKDN_inf RNF40 protein_coding   26.85609 22.35306 26.94216 0.9691217 0.5631954 0.2692833 4.428182 1.058834 9.585828 0.8474068 0.4221311 3.1663696 0.16210000 0.050875 0.356500 0.305625 0.01285284 0.01285284 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103549 E001 0.0000000       16 30761745 30762051 307 +      
ENSG00000103549 E002 0.4820432 0.0280794051 0.44679814   16 30762289 30762321 33 + 0.219 0.105 -1.252
ENSG00000103549 E003 0.6088971 0.0194461917 0.85107633 0.94726602 16 30762322 30762322 1 + 0.219 0.190 -0.252
ENSG00000103549 E004 1.2184548 0.2668537809 0.99699701 1.00000000 16 30762323 30762335 13 + 0.364 0.322 -0.254
ENSG00000103549 E005 3.9155053 0.0087996004 0.76776245 0.91012505 16 30762336 30762360 25 + 0.673 0.709 0.152
ENSG00000103549 E006 0.8364535 0.0125173445 0.09413342 0.31930194 16 30762361 30762398 38 + 0.363 0.105 -2.252
ENSG00000103549 E007 7.2142454 0.0102353554 0.81521907 0.93242787 16 30762475 30762534 60 + 0.902 0.925 0.088
ENSG00000103549 E008 15.2478332 0.0025713423 0.96239300 0.99183505 16 30762535 30762677 143 + 1.211 1.207 -0.015
ENSG00000103549 E009 22.1489655 0.0022867874 0.51621727 0.77198564 16 30763118 30763285 168 + 1.382 1.340 -0.147
ENSG00000103549 E010 19.7503754 0.0008376925 0.94983279 0.98694335 16 30763418 30763559 142 + 1.314 1.318 0.011
ENSG00000103549 E011 10.6598024 0.0013795512 0.23495207 0.52409526 16 30764179 30764264 86 + 1.016 1.117 0.366
ENSG00000103549 E012 13.8045398 0.0010849222 0.56648533 0.80469535 16 30764265 30764385 121 + 1.149 1.192 0.154
ENSG00000103549 E013 10.9647401 0.0012519016 0.86793192 0.95472980 16 30764938 30765000 63 + 1.084 1.069 -0.054
ENSG00000103549 E014 13.5561802 0.0012778866 0.71495091 0.88509761 16 30765001 30765059 59 + 1.149 1.176 0.099
ENSG00000103549 E015 26.5737889 0.0004943505 0.85094112 0.94724188 16 30765181 30765327 147 + 1.444 1.433 -0.040
ENSG00000103549 E016 13.1434659 0.0011513952 0.59560177 0.82221742 16 30765425 30765499 75 + 1.168 1.126 -0.152
ENSG00000103549 E017 22.3938430 0.0006388450 0.42484424 0.70399937 16 30766163 30766282 120 + 1.390 1.340 -0.174
ENSG00000103549 E018 35.2214796 0.0135524286 0.16747174 0.43808334 16 30766379 30766558 180 + 1.598 1.506 -0.314
ENSG00000103549 E019 0.6339843 0.0158052383 0.01029131 0.08180566 16 30766559 30766740 182 + 0.000 0.375 10.781
ENSG00000103549 E020 29.9492618 0.0005179578 0.38256457 0.66883673 16 30766741 30766876 136 + 1.468 1.513 0.156
ENSG00000103549 E021 0.8706031 0.0124115865 0.14931484 0.41154993 16 30767677 30767893 217 + 0.157 0.375 1.655
ENSG00000103549 E022 28.7228522 0.0005939271 0.33355357 0.62556082 16 30767894 30768015 122 + 1.496 1.442 -0.186
ENSG00000103549 E023 54.4209806 0.0030179407 0.86821142 0.95481658 16 30768103 30768530 428 + 1.739 1.746 0.021
ENSG00000103549 E024 0.0000000       16 30768531 30768531 1 +      
ENSG00000103549 E025 8.6188191 0.0016137894 0.19756004 0.47884249 16 30768619 30768622 4 + 1.034 0.911 -0.458
ENSG00000103549 E026 23.6636999 0.0005809053 0.03782535 0.18768797 16 30768623 30768736 114 + 1.444 1.318 -0.440
ENSG00000103549 E027 44.0138529 0.0003754248 0.86592520 0.95378037 16 30768838 30768987 150 + 1.656 1.647 -0.028
ENSG00000103549 E028 50.3970409 0.0002976833 0.10451500 0.33792412 16 30769186 30769338 153 + 1.678 1.743 0.221
ENSG00000103549 E029 30.3132426 0.0006176086 0.40990088 0.69201266 16 30769339 30769398 60 + 1.474 1.517 0.147
ENSG00000103549 E030 0.9695047 0.0137668240 0.70458397 0.87991187 16 30769399 30769474 76 + 0.320 0.261 -0.404
ENSG00000103549 E031 36.4922615 0.0003629995 0.73626379 0.89534028 16 30769475 30769600 126 + 1.565 1.581 0.052
ENSG00000103549 E032 36.8474878 0.0004212468 0.76734959 0.90988438 16 30771833 30771973 141 + 1.571 1.584 0.046
ENSG00000103549 E033 20.9363909 0.0007226103 0.19463557 0.47461077 16 30772089 30772190 102 + 1.300 1.382 0.282
ENSG00000103549 E034 0.0000000       16 30773815 30773937 123 +      
ENSG00000103549 E035 0.0000000       16 30773938 30774069 132 +      
ENSG00000103549 E036 0.0000000       16 30774070 30774185 116 +      
ENSG00000103549 E037 0.0000000       16 30774186 30774313 128 +      
ENSG00000103549 E038 1.2277124 0.1564939846 0.82098982 0.93501450 16 30774314 30776307 1994 + 0.320 0.375 0.332

Help

Please Click HERE to learn more details about the results from DEXseq.