ENSG00000103978

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389834 ENSG00000103978 No_inf pgKDN_inf TMEM87A protein_coding protein_coding 48.18618 49.37651 49.98747 2.245341 4.218064 0.0177382 31.142896 24.806675 34.154914 1.8960367 3.884624 0.46120565 0.66050000 0.507525 0.70325 0.195725 0.427099381 0.0003832563 FALSE TRUE
ENST00000568067 ENSG00000103978 No_inf pgKDN_inf TMEM87A protein_coding retained_intron 48.18618 49.37651 49.98747 2.245341 4.218064 0.0177382 5.615195 6.563049 6.144260 2.2139635 4.569428 -0.09497732 0.10560833 0.128425 0.10435 -0.024075 0.819241740 0.0003832563   FALSE
MSTRG.9464.2 ENSG00000103978 No_inf pgKDN_inf TMEM87A protein_coding   48.18618 49.37651 49.98747 2.245341 4.218064 0.0177382 2.171593 6.118898 0.395881 0.8043006 0.395881 -3.91649881 0.04388333 0.125150 0.00650 -0.118650 0.002809125 0.0003832563 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000103978 E001 0.2454921 0.0164710362 0.9614508618   15 42210447 42210527 81 - 0.097 0.093 -0.073
ENSG00000103978 E002 0.3809703 0.0297133582 0.1176679559   15 42210528 42210531 4 - 0.000 0.235 11.483
ENSG00000103978 E003 9.3516184 0.0016209864 0.3833133394 0.6694608869 15 42210532 42210578 47 - 0.968 1.052 0.309
ENSG00000103978 E004 10.5767199 0.0025419046 0.4357186021 0.7122678428 15 42210579 42210591 13 - 1.023 1.095 0.264
ENSG00000103978 E005 152.4219890 0.0003193251 0.0081943271 0.0702404380 15 42210592 42211138 547 - 2.149 2.215 0.221
ENSG00000103978 E006 131.9802052 0.0040179048 0.2478443597 0.5386077503 15 42211139 42211749 611 - 2.099 2.143 0.145
ENSG00000103978 E007 30.2633920 0.0005629241 0.8647899947 0.9532336212 15 42217803 42217833 31 - 1.497 1.492 -0.014
ENSG00000103978 E008 0.2435110 0.0164880639 0.9612296739   15 42217834 42218006 173 - 0.097 0.093 -0.073
ENSG00000103978 E009 41.4817238 0.0003240920 0.6006484704 0.8251706514 15 42218323 42218375 53 - 1.612 1.641 0.098
ENSG00000103978 E010 28.4309545 0.0005455260 0.7329443932 0.8938128866 15 42218376 42218378 3 - 1.475 1.461 -0.048
ENSG00000103978 E011 46.3581112 0.0003059068 0.9886682097 1.0000000000 15 42219581 42219639 59 - 1.672 1.677 0.019
ENSG00000103978 E012 25.3552380 0.0005493275 0.6053731845 0.8280315572 15 42219640 42219642 3 - 1.433 1.408 -0.087
ENSG00000103978 E013 25.3461407 0.0005470732 0.5119721073 0.7691062664 15 42220062 42220135 74 - 1.437 1.404 -0.115
ENSG00000103978 E014 0.2435110 0.0164880639 0.9612296739   15 42226603 42226805 203 - 0.097 0.093 -0.073
ENSG00000103978 E015 0.0000000       15 42226806 42226909 104 -      
ENSG00000103978 E016 0.0000000       15 42227615 42227710 96 -      
ENSG00000103978 E017 10.6030053 0.0013705585 0.1443983243 0.4045558570 15 42227711 42227769 59 - 1.124 1.003 -0.439
ENSG00000103978 E018 28.6124052 0.0082026971 0.3935036951 0.6783835158 15 42228712 42228820 109 - 1.497 1.447 -0.171
ENSG00000103978 E019 21.0291697 0.0006700216 0.3094399976 0.6027860307 15 42231192 42231260 69 - 1.373 1.313 -0.207
ENSG00000103978 E020 1.5880675 0.0087202931 0.7004376400 0.8779521642 15 42231844 42231915 72 - 0.440 0.386 -0.295
ENSG00000103978 E021 0.9895845 0.0173928134 0.5397854997 0.7881225420 15 42232879 42233212 334 - 0.244 0.341 0.664
ENSG00000103978 E022 23.7923916 0.0006246544 0.0374032926 0.1862829092 15 42233213 42233306 94 - 1.453 1.333 -0.415
ENSG00000103978 E023 14.3718760 0.0009642916 0.6214249259 0.8366878136 15 42236320 42236354 35 - 1.163 1.205 0.150
ENSG00000103978 E024 17.2041143 0.0008104010 0.5183231196 0.7734646542 15 42236355 42236419 65 - 1.232 1.282 0.175
ENSG00000103978 E025 28.0086570 0.0010379714 0.4744998145 0.7412290157 15 42237432 42237544 113 - 1.437 1.482 0.156
ENSG00000103978 E026 22.4772231 0.0007127623 0.1925195110 0.4724095657 15 42237545 42237615 71 - 1.408 1.333 -0.261
ENSG00000103978 E027 0.0000000       15 42239668 42239669 2 -      
ENSG00000103978 E028 21.9728716 0.0067913130 0.1565013046 0.4227557529 15 42239670 42239731 62 - 1.408 1.313 -0.330
ENSG00000103978 E029 22.3623583 0.0006692697 0.2180651972 0.5045096235 15 42244050 42244131 82 - 1.404 1.333 -0.246
ENSG00000103978 E030 13.5237328 0.0015123492 0.0547212214 0.2329755568 15 42244132 42244167 36 - 1.232 1.087 -0.518
ENSG00000103978 E031 6.8416274 0.0021542017 0.4479609579 0.7221306843 15 42257935 42258790 856 - 0.931 0.858 -0.279
ENSG00000103978 E032 2.5473524 0.0056743587 0.2212967387 0.5084093672 15 42258791 42258990 200 - 0.630 0.464 -0.773
ENSG00000103978 E033 17.3422595 0.0008813783 0.2280755605 0.5165296571 15 42260958 42261002 45 - 1.303 1.224 -0.276
ENSG00000103978 E034 16.6555045 0.0008649217 0.7177215815 0.8864928268 15 42261196 42261249 54 - 1.257 1.236 -0.073
ENSG00000103978 E035 0.2444846 0.0164267476 0.9617298640   15 42262123 42262243 121 - 0.097 0.093 -0.073
ENSG00000103978 E036 25.5793340 0.0006090770 0.4261525898 0.7049044280 15 42264090 42264203 114 - 1.445 1.404 -0.142
ENSG00000103978 E037 23.3588813 0.0006032839 0.2799841836 0.5732543831 15 42267947 42268032 86 - 1.417 1.356 -0.209
ENSG00000103978 E038 0.1271363 0.0123555334 0.5724789365   15 42271555 42271601 47 - 0.000 0.093 10.073
ENSG00000103978 E039 12.6131680 0.0161860721 0.7246831917 0.8894030719 15 42272063 42272123 61 - 1.148 1.120 -0.101
ENSG00000103978 E040 2.1589916 0.0071160062 0.0000055766 0.0002067136 15 42272676 42272888 213 - 0.000 0.704 13.875
ENSG00000103978 E041 2.0211860 0.0068770949 0.0002348871 0.0047715251 15 42272889 42272962 74 - 0.097 0.661 3.834
ENSG00000103978 E042 2.5208580 0.0267574247 0.0004426150 0.0079388092 15 42272963 42273254 292 - 0.177 0.724 3.097
ENSG00000103978 E043 0.0000000       15 42273255 42273534 280 -      

Help

Please Click HERE to learn more details about the results from DEXseq.