ENSG00000104043

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000284509 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding protein_coding 43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 4.637089 2.0347138 2.6748189 1.1797381 2.6748189 0.39292585 0.10004167 0.062050 0.059575 -0.002475 0.78362945 0.04768156 FALSE TRUE
ENST00000558458 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding nonsense_mediated_decay 43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 3.244212 2.5378455 4.6915895 0.2694528 1.2790485 0.88387080 0.07681667 0.085725 0.096375 0.010650 0.99661659 0.04768156 TRUE FALSE
ENST00000558498 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding protein_coding_CDS_not_defined 43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 8.957280 7.5922079 7.1679227 0.3391539 0.7360742 -0.08285209 0.21244167 0.250975 0.153475 -0.097500 0.42926088 0.04768156 FALSE TRUE
MSTRG.9496.1 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding   43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 2.547453 1.0892680 3.6841380 0.8074647 2.1765418 1.74869461 0.05546667 0.037525 0.073225 0.035700 0.96956534 0.04768156 FALSE TRUE
MSTRG.9496.16 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding   43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 3.799657 2.7275481 3.1748420 2.0696811 1.8372445 0.21833748 0.08149167 0.077050 0.061575 -0.015475 1.00000000 0.04768156   FALSE
MSTRG.9496.2 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding   43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 2.964914 1.1795528 3.3112180 0.8318432 1.9187677 1.48129318 0.06859167 0.044575 0.076150 0.031575 0.99435148 0.04768156 FALSE TRUE
MSTRG.9496.6 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding   43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 2.500439 0.4464285 7.0548900 0.4464285 2.5649590 3.95220642 0.05642500 0.017300 0.151975 0.134675 0.27407412 0.04768156 FALSE TRUE
MSTRG.9496.7 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding   43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 1.597885 2.6529483 0.5544625 0.4746250 0.2575168 -2.23807485 0.04447500 0.089375 0.012375 -0.077000 0.04768156 0.04768156 FALSE TRUE
MSTRG.9496.8 ENSG00000104043 No_inf pgKDN_inf ATP8B4 protein_coding   43.41806 30.67167 47.74002 2.515745 3.626777 0.6381242 7.182589 5.6765441 9.0720084 1.0062546 2.0650972 0.67545924 0.16675000 0.184825 0.184650 -0.000175 1.00000000 0.04768156 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104043 E001 0.1170040 0.0117147149 1.000000e+00   15 49858167 49858186 20 - 0.075 0.000 -9.660
ENSG00000104043 E002 0.2454921 0.0164792385 6.918849e-01   15 49858187 49858237 51 - 0.075 0.119 0.736
ENSG00000104043 E003 0.2454921 0.0164792385 6.918849e-01   15 49858238 49858238 1 - 0.075 0.119 0.736
ENSG00000104043 E004 0.3723461 0.1999065511 3.653596e-01   15 49858239 49858240 2 - 0.075 0.213 1.736
ENSG00000104043 E005 0.8634603 0.5331655299 7.188199e-01 8.868007e-01 15 49858241 49858248 8 - 0.196 0.355 1.148
ENSG00000104043 E006 1.3628781 0.1139848674 1.346506e-01 3.901421e-01 15 49858249 49858250 2 - 0.245 0.507 1.542
ENSG00000104043 E007 124.1679379 0.0010889277 2.106630e-07 1.140753e-05 15 49858251 49858999 749 - 2.024 2.170 0.489
ENSG00000104043 E008 11.9757925 0.0012343398 3.712323e-02 1.855573e-01 15 49859000 49859001 2 - 1.028 1.200 0.618
ENSG00000104043 E009 114.7586105 0.0001532696 5.952585e-02 2.446631e-01 15 49859002 49859638 637 - 2.033 2.084 0.173
ENSG00000104043 E010 90.0422475 0.0001910005 2.752191e-01 5.687228e-01 15 49859639 49860213 575 - 1.935 1.970 0.115
ENSG00000104043 E011 38.9626944 0.0003514468 6.591630e-02 2.585800e-01 15 49860214 49860456 243 - 1.555 1.643 0.300
ENSG00000104043 E012 9.3396466 0.0021222136 9.807871e-01 9.979770e-01 15 49860457 49860475 19 - 1.004 1.007 0.009
ENSG00000104043 E013 19.4842267 0.0007383549 1.987850e-01 4.802222e-01 15 49862245 49862375 131 - 1.266 1.352 0.300
ENSG00000104043 E014 22.1453035 0.0014537629 1.932992e-01 4.731080e-01 15 49866346 49866484 139 - 1.320 1.404 0.289
ENSG00000104043 E015 29.1001777 0.0100496370 9.634056e-01 9.922870e-01 15 49876278 49876523 246 - 1.469 1.469 0.000
ENSG00000104043 E016 0.1265070 0.0122439237 3.152981e-01   15 49876524 49876606 83 - 0.000 0.119 12.361
ENSG00000104043 E017 0.0000000       15 49876643 49876695 53 -      
ENSG00000104043 E018 16.7513803 0.0010961869 7.009034e-01 8.781802e-01 15 49879376 49879459 84 - 1.229 1.257 0.099
ENSG00000104043 E019 0.5991122 0.0142656069 4.134276e-01 6.941814e-01 15 49879460 49879588 129 - 0.245 0.119 -1.264
ENSG00000104043 E020 0.1268540 0.0123068174 3.152275e-01   15 49883141 49883158 18 - 0.000 0.119 12.361
ENSG00000104043 E021 0.0000000       15 49883159 49883208 50 -      
ENSG00000104043 E022 0.0000000       15 49883335 49883392 58 -      
ENSG00000104043 E023 1.3526135 0.0107823330 2.603680e-01 5.530359e-01 15 49885811 49885925 115 - 0.290 0.462 0.999
ENSG00000104043 E024 2.2054336 0.0097387713 2.931109e-01 5.867399e-01 15 49885926 49886121 196 - 0.432 0.585 0.736
ENSG00000104043 E025 2.8062481 0.0826624863 3.895199e-01 6.752279e-01 15 49889130 49889281 152 - 0.515 0.651 0.612
ENSG00000104043 E026 12.8068036 0.0013078674 1.711652e-01 4.434652e-01 15 49894892 49897291 2400 - 1.172 1.058 -0.409
ENSG00000104043 E027 23.0146663 0.0006226043 4.239881e-01 7.031787e-01 15 49897292 49897434 143 - 1.389 1.339 -0.174
ENSG00000104043 E028 15.7814258 0.0011752764 9.714531e-01 9.945334e-01 15 49897435 49897515 81 - 1.214 1.217 0.011
ENSG00000104043 E029 14.6609960 0.0008822772 6.500492e-01 8.526050e-01 15 49898068 49898145 78 - 1.198 1.164 -0.123
ENSG00000104043 E030 18.3812432 0.0058483956 2.715529e-01 5.652837e-01 15 49898146 49898251 106 - 1.308 1.225 -0.293
ENSG00000104043 E031 23.7323625 0.0202291865 3.900504e-01 6.755179e-01 15 49901092 49901239 148 - 1.409 1.339 -0.243
ENSG00000104043 E032 0.6181209 0.0233601753 3.166785e-01 6.095340e-01 15 49901787 49902283 497 - 0.140 0.290 1.321
ENSG00000104043 E033 0.2441403 0.0165332570 6.914025e-01   15 49908045 49908093 49 - 0.075 0.119 0.736
ENSG00000104043 E034 20.6190952 0.0026221992 7.837213e-01 9.167836e-01 15 49916934 49917039 106 - 1.332 1.314 -0.065
ENSG00000104043 E035 0.1170040 0.0117147149 1.000000e+00   15 49917040 49917276 237 - 0.075 0.000 -12.368
ENSG00000104043 E036 17.8333682 0.0046093866 2.734905e-02 1.539551e-01 15 49918839 49918950 112 - 1.324 1.154 -0.600
ENSG00000104043 E037 0.0000000       15 49919760 49919786 27 -      
ENSG00000104043 E038 9.4947017 0.0015326594 2.202528e-02 1.347755e-01 15 49920246 49920273 28 - 1.086 0.864 -0.825
ENSG00000104043 E039 21.4920362 0.0006506638 6.403285e-02 2.549120e-01 15 49920274 49920410 137 - 1.386 1.264 -0.425
ENSG00000104043 E040 3.8918138 0.0045663796 7.231513e-01 8.887420e-01 15 49922224 49922405 182 - 0.663 0.708 0.189
ENSG00000104043 E041 14.7651295 0.0029849296 4.883028e-01 7.516446e-01 15 49923379 49923494 116 - 1.209 1.154 -0.194
ENSG00000104043 E042 17.1724224 0.0007942417 2.725627e-01 5.662336e-01 15 49931119 49931307 189 - 1.279 1.200 -0.279
ENSG00000104043 E043 17.0728339 0.0008546166 1.121340e-03 1.637648e-02 15 49934017 49934182 166 - 1.328 1.081 -0.876
ENSG00000104043 E044 9.4989875 0.0059683865 1.436127e-02 1.020233e-01 15 49961977 49962020 44 - 1.093 0.845 -0.923
ENSG00000104043 E045 19.3999944 0.0007117430 1.045424e-02 8.268646e-02 15 49972582 49972790 209 - 1.362 1.182 -0.630
ENSG00000104043 E046 0.9732229 0.3457051897 9.032082e-01 9.689049e-01 15 49979412 49979605 194 - 0.290 0.290 -0.003
ENSG00000104043 E047 0.4899771 0.0157966600 6.146103e-01   15 49979606 49979616 11 - 0.140 0.213 0.736
ENSG00000104043 E048 4.4322482 0.0115752583 1.825116e-02 1.192928e-01 15 49979617 49979626 10 - 0.825 0.507 -1.364
ENSG00000104043 E049 14.2955263 0.0011178203 5.322316e-01 7.826320e-01 15 49979627 49979770 144 - 1.193 1.145 -0.173
ENSG00000104043 E050 5.9944967 0.0096388415 2.482734e-02 1.448705e-01 15 49979771 49979813 43 - 0.924 0.651 -1.090
ENSG00000104043 E051 9.0774164 0.0377917140 7.430877e-01 8.983949e-01 15 49981206 49981294 89 - 1.012 0.964 -0.178
ENSG00000104043 E052 13.3274147 0.0023833582 8.031999e-01 9.268841e-01 15 49987391 49987511 121 - 1.155 1.135 -0.071
ENSG00000104043 E053 9.2163285 0.0180409408 9.259004e-01 9.777382e-01 15 49987512 49987549 38 - 0.996 1.007 0.040
ENSG00000104043 E054 9.5136509 0.0070014666 1.355641e-01 3.913034e-01 15 49996677 49996759 83 - 1.065 0.917 -0.548
ENSG00000104043 E055 6.9730669 0.0066253086 6.836983e-02 2.638988e-01 15 50002153 50002223 71 - 0.962 0.759 -0.783
ENSG00000104043 E056 0.8704120 0.0297559225 7.590099e-02 2.815242e-01 15 50009272 50009676 405 - 0.140 0.412 2.058
ENSG00000104043 E057 6.8279559 0.0300878632 9.627728e-03 7.841133e-02 15 50010845 50010917 73 - 0.988 0.651 -1.329
ENSG00000104043 E058 0.7446279 0.0285353789 1.579589e-01 4.247372e-01 15 50018889 50018976 88 - 0.140 0.355 1.736
ENSG00000104043 E059 7.4838139 0.0771288127 2.977362e-01 5.908186e-01 15 50038768 50038829 62 - 0.971 0.825 -0.555
ENSG00000104043 E060 11.6585086 0.0011763654 6.807935e-01 8.681671e-01 15 50044594 50044692 99 - 1.079 1.114 0.126
ENSG00000104043 E061 8.4783657 0.0017050732 7.546617e-01 9.035120e-01 15 50047351 50047391 41 - 0.979 0.949 -0.112
ENSG00000104043 E062 11.4787852 0.0011479824 2.277381e-01 5.161718e-01 15 50047392 50047464 73 - 1.125 1.020 -0.380
ENSG00000104043 E063 9.7376022 0.0290389723 4.536749e-02 2.083135e-01 15 50074127 50074185 59 - 1.099 0.864 -0.873
ENSG00000104043 E064 6.9859858 0.0273229417 1.746779e-01 4.484947e-01 15 50106939 50107004 66 - 0.953 0.782 -0.656
ENSG00000104043 E065 2.3135668 0.0066133030 6.853708e-01 8.700259e-01 15 50107005 50107008 4 - 0.489 0.547 0.277
ENSG00000104043 E066 0.2539903 0.0160854868 1.114409e-01   15 50108045 50108102 58 - 0.000 0.213 13.294
ENSG00000104043 E067 0.1272623 0.0124504466 3.151141e-01   15 50113198 50113316 119 - 0.000 0.119 12.360
ENSG00000104043 E068 0.2543986 0.0161393080 1.113391e-01   15 50114426 50114504 79 - 0.000 0.213 13.294
ENSG00000104043 E069 3.0558048 0.0060351303 2.936428e-01 5.871798e-01 15 50119123 50119238 116 - 0.540 0.680 0.621
ENSG00000104043 E070 1.1899823 0.0116633091 5.104412e-02 2.236586e-01 15 50119332 50119481 150 - 0.432 0.119 -2.434
ENSG00000104043 E071 0.0000000       15 50182261 50182817 557 -      

Help

Please Click HERE to learn more details about the results from DEXseq.