ENSG00000104081

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354670 ENSG00000104081 No_inf pgKDN_inf BMF protein_coding protein_coding 39.12488 39.14759 38.77908 1.771834 1.819713 -0.01364126 6.875474 6.837464 10.0362551 2.465446 0.8576251 0.5530160 0.17775000 0.178150 0.262225 0.084075 8.159227e-01 1.568344e-06 FALSE  
ENST00000397573 ENSG00000104081 No_inf pgKDN_inf BMF protein_coding protein_coding 39.12488 39.14759 38.77908 1.771834 1.819713 -0.01364126 2.061303 1.225532 0.6436276 1.225532 0.6436276 -0.9185922 0.05420000 0.029175 0.016850 -0.012325 1.000000e+00 1.568344e-06 FALSE  
ENST00000561360 ENSG00000104081 No_inf pgKDN_inf BMF protein_coding protein_coding 39.12488 39.14759 38.77908 1.771834 1.819713 -0.01364126 1.361707 2.652416 0.3213580 1.029088 0.1923087 -3.0062730 0.03411667 0.067075 0.007800 -0.059275 4.305674e-01 1.568344e-06 FALSE  
MSTRG.9305.1 ENSG00000104081 No_inf pgKDN_inf BMF protein_coding   39.12488 39.14759 38.77908 1.771834 1.819713 -0.01364126 1.862040 0.000000 3.6943739 0.000000 0.5127595 8.5330859 0.04820833 0.000000 0.097375 0.097375 1.568344e-06 1.568344e-06    
MSTRG.9305.4 ENSG00000104081 No_inf pgKDN_inf BMF protein_coding   39.12488 39.14759 38.77908 1.771834 1.819713 -0.01364126 17.858205 20.818897 16.7139527 1.246641 1.4327840 -0.3166706 0.45749167 0.533250 0.432900 -0.100350 5.972037e-01 1.568344e-06    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104081 E001 0.1271363 0.0123958713 5.360865e-01   15 40087890 40087892 3 - 0.000 0.095 9.903
ENSG00000104081 E002 0.2543986 0.0160818800 2.409340e-01   15 40087893 40087893 1 - 0.000 0.173 12.727
ENSG00000104081 E003 432.2886194 0.0001920250 2.647690e-02 1.508064e-01 15 40087894 40091009 3116 - 2.626 2.646 0.066
ENSG00000104081 E004 28.0270967 0.0007981177 7.666084e-01 9.094285e-01 15 40091010 40091201 192 - 1.472 1.454 -0.062
ENSG00000104081 E005 20.5553629 0.0064590608 9.228500e-01 9.763295e-01 15 40091202 40091288 87 - 1.338 1.329 -0.033
ENSG00000104081 E006 32.3263996 0.0107484947 9.031479e-01 9.688647e-01 15 40091289 40091441 153 - 1.519 1.526 0.023
ENSG00000104081 E007 46.5138089 0.0002965343 8.662638e-01 9.539942e-01 15 40091442 40091675 234 - 1.681 1.672 -0.029
ENSG00000104081 E008 15.0122985 0.0009235590 4.317574e-01 7.093458e-01 15 40091676 40091717 42 - 1.234 1.175 -0.211
ENSG00000104081 E009 10.4893938 0.0022247178 4.068892e-01 6.894706e-01 15 40091718 40091733 16 - 1.097 1.023 -0.268
ENSG00000104081 E010 11.8783851 0.0044480806 1.194499e-02 9.021718e-02 15 40091734 40091786 53 - 1.209 0.992 -0.783
ENSG00000104081 E011 8.8685298 0.0016794138 8.385633e-02 2.987454e-01 15 40091787 40091790 4 - 1.071 0.909 -0.600
ENSG00000104081 E012 18.8031972 0.0008686375 3.470865e-01 6.376529e-01 15 40091791 40091888 98 - 1.329 1.264 -0.224
ENSG00000104081 E013 0.6244140 0.1563352361 2.226476e-01 5.099653e-01 15 40093603 40093652 50 - 0.095 0.296 2.001
ENSG00000104081 E014 11.7569942 0.0013284248 9.857204e-01 9.990789e-01 15 40104180 40104242 63 - 1.105 1.106 0.001
ENSG00000104081 E015 13.5525205 0.0020208601 4.116574e-01 6.931946e-01 15 40104243 40104340 98 - 1.195 1.130 -0.234
ENSG00000104081 E016 2.3594986 0.0058598153 4.067929e-07 2.050465e-05 15 40104939 40105259 321 - 0.770 0.000 -16.633
ENSG00000104081 E017 13.9508612 0.0010752510 8.683591e-01 9.548371e-01 15 40105795 40105902 108 - 1.182 1.168 -0.050
ENSG00000104081 E018 17.1219621 0.0008400632 6.290524e-01 8.409693e-01 15 40105903 40106047 145 - 1.276 1.241 -0.123
ENSG00000104081 E019 6.3666888 0.0431181257 9.706385e-01 9.941400e-01 15 40106048 40106091 44 - 0.867 0.867 0.000
ENSG00000104081 E020 0.4994828 0.0340662021 3.218086e-01   15 40106092 40106093 2 - 0.095 0.239 1.586
ENSG00000104081 E021 2.2584617 0.1270896535 1.966266e-02 1.256053e-01 15 40106094 40106304 211 - 0.239 0.670 2.323
ENSG00000104081 E022 2.0543065 0.1068716417 1.707000e-01 4.430266e-01 15 40106305 40106357 53 - 0.595 0.347 -1.263
ENSG00000104081 E023 2.7186644 0.0198550109 2.161990e-01 5.023361e-01 15 40106358 40106438 81 - 0.471 0.646 0.808
ENSG00000104081 E024 0.5004251 0.5020489282 5.746728e-01 8.095769e-01 15 40106439 40106448 10 - 0.095 0.239 1.586
ENSG00000104081 E025 2.7318867 0.0176840558 9.721972e-02 3.247522e-01 15 40106584 40106890 307 - 0.433 0.670 1.101
ENSG00000104081 E026 1.0963338 0.0845404737 7.649271e-01 9.085131e-01 15 40106891 40106930 40 - 0.347 0.297 -0.321
ENSG00000104081 E027 0.4827683 0.5257303820 5.834272e-01   15 40108043 40108258 216 - 0.239 0.095 -1.586
ENSG00000104081 E028 7.6012992 0.0028118899 7.927886e-01 9.209338e-01 15 40108259 40108357 99 - 0.921 0.946 0.094
ENSG00000104081 E029 3.6561980 0.0041402955 4.763783e-01 7.428725e-01 15 40108358 40108386 29 - 0.713 0.621 -0.386
ENSG00000104081 E030 2.8242187 0.0114439420 5.369374e-01 7.861261e-01 15 40108387 40108704 318 - 0.537 0.621 0.380
ENSG00000104081 E031 3.1776737 0.0050037876 7.064707e-01 8.809224e-01 15 40108773 40108892 120 - 0.646 0.595 -0.221

Help

Please Click HERE to learn more details about the results from DEXseq.