ENSG00000104517

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000220959 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding protein_coding 69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 3.310549 0.4581164 4.910148 0.4581164 0.6697484 3.3937626 0.04721667 0.006675 0.073500 0.066825 0.01864112 0.01641372 FALSE  
ENST00000517465 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding retained_intron 69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 15.007739 21.6450976 10.973222 2.3948087 2.4272014 -0.9794053 0.21671667 0.316625 0.163025 -0.153600 0.14772209 0.01641372 TRUE  
ENST00000518205 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding protein_coding 69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 18.294032 14.9144975 19.161103 1.1361246 0.5751100 0.3612510 0.26273333 0.219975 0.288500 0.068525 0.56264644 0.01641372 FALSE  
ENST00000521566 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding protein_coding 69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 4.593264 0.0000000 5.062106 0.0000000 1.8529140 8.9864412 0.06356667 0.000000 0.077700 0.077700 0.01641372 0.01641372 FALSE  
MSTRG.28050.3 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding   69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 5.173802 5.0271810 5.661228 0.7939675 0.6668044 0.1710446 0.07568333 0.074475 0.085450 0.010975 0.90386031 0.01641372 FALSE  
MSTRG.28050.4 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding   69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 9.594378 12.4012307 8.002032 0.3257977 1.1572780 -0.6314062 0.13861667 0.182325 0.119600 -0.062725 0.48215630 0.01641372 FALSE  
MSTRG.28050.6 ENSG00000104517 No_inf pgKDN_inf UBR5 protein_coding   69.5575 68.0583 66.54077 1.280269 1.343162 -0.03252782 3.734460 5.4011764 3.044459 1.0947301 1.8337789 -0.8250254 0.05490000 0.079750 0.047325 -0.032425 0.61755459 0.01641372 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104517 E001 0.0000000       8 102252273 102252283 11 -      
ENSG00000104517 E002 0.0000000       8 102252284 102252306 23 -      
ENSG00000104517 E003 0.0000000       8 102252307 102252307 1 -      
ENSG00000104517 E004 0.0000000       8 102252308 102253735 1428 -      
ENSG00000104517 E005 49.8264064 0.0039172870 6.131173e-04 1.021911e-02 8 102253736 102253945 210 - 1.610 1.781 0.582
ENSG00000104517 E006 94.9694733 0.0001870316 2.073324e-06 8.770404e-05 8 102253946 102254197 252 - 1.900 2.048 0.497
ENSG00000104517 E007 59.2123877 0.0003102276 3.387255e-02 1.751565e-01 8 102254198 102254309 112 - 1.734 1.819 0.285
ENSG00000104517 E008 68.7280915 0.0004173363 6.889783e-02 2.651936e-01 8 102254310 102254467 158 - 1.807 1.875 0.229
ENSG00000104517 E009 15.6507932 0.0031223568 8.129454e-01 9.313356e-01 8 102254468 102254514 47 - 1.230 1.213 -0.058
ENSG00000104517 E010 0.0000000       8 102257632 102257717 86 -      
ENSG00000104517 E011 3.4750134 0.0046678068 5.325263e-02 2.296599e-01 8 102258316 102258424 109 - 0.502 0.756 1.111
ENSG00000104517 E012 48.0877855 0.0010597138 1.378173e-04 3.088093e-03 8 102258985 102259129 145 - 1.594 1.767 0.587
ENSG00000104517 E013 53.4003509 0.0002757325 1.732215e-05 5.453900e-04 8 102261146 102261259 114 - 1.635 1.814 0.606
ENSG00000104517 E014 66.8592349 0.0003132844 1.683314e-01 4.395305e-01 8 102261915 102262070 156 - 1.804 1.856 0.176
ENSG00000104517 E015 46.7472845 0.0003939806 9.049224e-01 9.695450e-01 8 102264474 102264558 85 - 1.681 1.677 -0.013
ENSG00000104517 E016 46.1872481 0.0003529928 6.589465e-01 8.575929e-01 8 102265100 102265202 103 - 1.663 1.684 0.071
ENSG00000104517 E017 21.8657219 0.0007161315 2.437095e-01 5.337324e-01 8 102265203 102265207 5 - 1.319 1.394 0.260
ENSG00000104517 E018 32.1752698 0.0022044682 1.892911e-01 4.679054e-01 8 102265208 102265275 68 - 1.481 1.555 0.253
ENSG00000104517 E019 11.4274744 0.0012016349 3.096033e-01 6.029300e-01 8 102265276 102265278 3 - 1.048 1.134 0.313
ENSG00000104517 E020 25.6450289 0.0005771469 3.389027e-01 6.305579e-01 8 102266947 102267007 61 - 1.453 1.398 -0.188
ENSG00000104517 E021 2.1235252 0.0712008598 4.968668e-02 2.198851e-01 8 102267008 102267092 85 - 0.294 0.625 1.733
ENSG00000104517 E022 22.4149517 0.0162071657 1.076808e-06 4.968056e-05 8 102267093 102268977 1885 - 1.109 1.524 1.451
ENSG00000104517 E023 43.5460009 0.0075241430 4.192244e-01 6.987592e-01 8 102268978 102269108 131 - 1.625 1.670 0.154
ENSG00000104517 E024 59.8878890 0.0002715323 3.839268e-01 6.700333e-01 8 102270039 102270183 145 - 1.801 1.768 -0.109
ENSG00000104517 E025 40.5279534 0.0041429087 7.537138e-01 9.031185e-01 8 102271134 102271193 60 - 1.609 1.627 0.059
ENSG00000104517 E026 32.3920667 0.0004683894 6.067299e-01 8.288396e-01 8 102271194 102271245 52 - 1.537 1.511 -0.087
ENSG00000104517 E027 74.1331074 0.0002077313 5.453809e-01 7.913429e-01 8 102272529 102272772 244 - 1.864 1.886 0.075
ENSG00000104517 E028 0.0000000       8 102272773 102272931 159 -      
ENSG00000104517 E029 1.0981215 0.0109700977 7.634423e-01 9.078092e-01 8 102275515 102275520 6 - 0.344 0.299 -0.289
ENSG00000104517 E030 39.3398937 0.0003658605 3.474265e-01 6.380679e-01 8 102275521 102275619 99 - 1.627 1.584 -0.147
ENSG00000104517 E031 45.8157826 0.0003303203 2.702573e-01 5.639760e-01 8 102275708 102275828 121 - 1.694 1.647 -0.160
ENSG00000104517 E032 0.3717469 0.0167735973 5.718660e-01   8 102276774 102276971 198 - 0.094 0.175 1.033
ENSG00000104517 E033 58.3775741 0.0002414834 2.221849e-01 5.094732e-01 8 102276972 102277192 221 - 1.748 1.797 0.166
ENSG00000104517 E034 29.8077168 0.0019493770 3.479699e-01 6.384776e-01 8 102278826 102278939 114 - 1.460 1.514 0.187
ENSG00000104517 E035 35.1417331 0.0003959764 9.022278e-02 3.119895e-01 8 102279036 102279166 131 - 1.511 1.598 0.296
ENSG00000104517 E036 21.5973340 0.0047252869 5.052863e-01 7.641303e-01 8 102279167 102279208 42 - 1.329 1.376 0.164
ENSG00000104517 E037 30.3237256 0.0020217660 6.455543e-01 8.499909e-01 8 102280394 102280467 74 - 1.508 1.484 -0.084
ENSG00000104517 E038 46.9162117 0.0002960790 2.552021e-01 5.471532e-01 8 102281289 102281519 231 - 1.704 1.656 -0.163
ENSG00000104517 E039 21.0717240 0.0006167014 7.761441e-02 2.850316e-01 8 102285127 102285244 118 - 1.397 1.286 -0.387
ENSG00000104517 E040 15.8816119 0.0008918327 5.578608e-01 7.996722e-01 8 102285245 102285338 94 - 1.248 1.207 -0.145
ENSG00000104517 E041 32.8673963 0.0004934675 1.142107e-02 8.780957e-02 8 102285513 102285781 269 - 1.456 1.590 0.457
ENSG00000104517 E042 32.7469296 0.0006338968 5.705574e-01 8.070060e-01 8 102286360 102286617 258 - 1.543 1.514 -0.097
ENSG00000104517 E043 18.7407281 0.0026725545 4.014587e-02 1.942056e-01 8 102287433 102287504 72 - 1.362 1.220 -0.498
ENSG00000104517 E044 18.7481062 0.0007857299 8.428893e-01 9.437711e-01 8 102287505 102287564 60 - 1.288 1.302 0.051
ENSG00000104517 E045 0.3807797 0.0298815187 1.014642e-01   8 102288147 102288154 8 - 0.000 0.241 11.532
ENSG00000104517 E046 20.6035260 0.0006459302 5.602212e-01 8.008633e-01 8 102288155 102288266 112 - 1.314 1.353 0.136
ENSG00000104517 E047 12.0318326 0.0012257723 3.718598e-01 6.597949e-01 8 102289453 102289528 76 - 1.075 1.150 0.269
ENSG00000104517 E048 13.3402491 0.0029279292 8.484200e-01 9.463268e-01 8 102289529 102289576 48 - 1.148 1.165 0.059
ENSG00000104517 E049 39.2627736 0.0003562617 6.730923e-02 2.616632e-01 8 102293605 102293844 240 - 1.647 1.561 -0.291
ENSG00000104517 E050 26.4977852 0.0023784348 1.009491e-02 8.081623e-02 8 102293955 102294115 161 - 1.511 1.358 -0.530
ENSG00000104517 E051 23.3377270 0.0005575008 9.308947e-03 7.675942e-02 8 102294982 102295111 130 - 1.460 1.302 -0.546
ENSG00000104517 E052 21.1966535 0.0014356476 7.142945e-02 2.708434e-01 8 102295204 102295330 127 - 1.401 1.286 -0.402
ENSG00000104517 E053 19.1184238 0.0089913507 1.019233e-01 3.334827e-01 8 102295414 102295532 119 - 1.362 1.239 -0.431
ENSG00000104517 E054 23.1934749 0.0006456506 2.442275e-01 5.343847e-01 8 102295636 102295782 147 - 1.418 1.348 -0.242
ENSG00000104517 E055 15.3743244 0.0009399391 2.588886e-01 5.514137e-01 8 102296893 102296984 92 - 1.254 1.172 -0.289
ENSG00000104517 E056 12.8917753 0.0117082841 6.026670e-01 8.266031e-01 8 102297458 102297606 149 - 1.117 1.165 0.170
ENSG00000104517 E057 14.6868507 0.0024605437 8.011862e-01 9.258678e-01 8 102298392 102298489 98 - 1.204 1.186 -0.064
ENSG00000104517 E058 6.9573672 0.0019416185 5.594485e-01 8.005013e-01 8 102298848 102298859 12 - 0.930 0.871 -0.221
ENSG00000104517 E059 7.3065175 0.0020367834 3.433981e-01 6.346011e-01 8 102298860 102298866 7 - 0.965 0.871 -0.354
ENSG00000104517 E060 13.1354842 0.0123450818 1.547550e-01 4.202696e-01 8 102298867 102298971 105 - 1.211 1.084 -0.453
ENSG00000104517 E061 8.2830364 0.0482044181 5.121944e-01 7.691995e-01 8 102299452 102299496 45 - 1.008 0.926 -0.308
ENSG00000104517 E062 7.8809437 0.0318318696 1.008165e-01 3.314299e-01 8 102299497 102299547 51 - 1.038 0.841 -0.740
ENSG00000104517 E063 16.0953038 0.0008452711 2.031671e-01 4.857085e-01 8 102300000 102300151 152 - 1.277 1.186 -0.319
ENSG00000104517 E064 3.1494508 0.0044896261 1.303443e-01 3.829806e-01 8 102302271 102302481 211 - 0.709 0.509 -0.885
ENSG00000104517 E065 14.4878241 0.0008900188 1.039531e-01 3.369406e-01 8 102304043 102304166 124 - 1.248 1.126 -0.432
ENSG00000104517 E066 6.3336037 0.0023837595 3.035855e-01 5.969318e-01 8 102304167 102304169 3 - 0.917 0.809 -0.415
ENSG00000104517 E067 20.8521794 0.0006580856 1.414285e-01 4.000316e-01 8 102305085 102305295 211 - 1.384 1.291 -0.324
ENSG00000104517 E068 15.7850514 0.0010786224 7.410773e-03 6.565254e-02 8 102311299 102311496 198 - 1.314 1.118 -0.693
ENSG00000104517 E069 13.8249513 0.0010524744 3.919022e-03 4.186344e-02 8 102311735 102311889 155 - 1.271 1.047 -0.800
ENSG00000104517 E070 12.7761820 0.0011023518 1.218913e-01 3.693951e-01 8 102312134 102312245 112 - 1.198 1.075 -0.439
ENSG00000104517 E071 13.5109962 0.0057079433 1.581350e-01 4.249552e-01 8 102312342 102312485 144 - 1.217 1.102 -0.413
ENSG00000104517 E072 9.7200527 0.0014952196 9.122488e-02 3.137814e-01 8 102313804 102313916 113 - 1.101 0.950 -0.552
ENSG00000104517 E073 8.8459048 0.0019800024 3.381497e-02 1.750217e-01 8 102314744 102314853 110 - 1.084 0.886 -0.736
ENSG00000104517 E074 13.3500205 0.0010050763 1.793624e-02 1.180299e-01 8 102323311 102323495 185 - 1.242 1.057 -0.663
ENSG00000104517 E075 10.4373737 0.0012963723 3.987842e-02 1.935345e-01 8 102326546 102326663 118 - 1.141 0.962 -0.651
ENSG00000104517 E076 11.6798352 0.0022687915 2.920213e-06 1.176242e-04 8 102327742 102327896 155 - 1.265 0.857 -1.494
ENSG00000104517 E077 9.3366345 0.0022321308 1.200914e-02 9.056219e-02 8 102329090 102329200 111 - 1.117 0.886 -0.857
ENSG00000104517 E078 8.6293694 0.0349880782 1.874986e-01 4.656134e-01 8 102329283 102329399 117 - 1.057 0.899 -0.587
ENSG00000104517 E079 10.1656057 0.0080228512 5.417038e-03 5.247172e-02 8 102342473 102342666 194 - 1.163 0.899 -0.968
ENSG00000104517 E080 0.8381526 0.0215744236 5.436027e-02 2.321847e-01 8 102342667 102342684 18 - 0.390 0.096 -2.553
ENSG00000104517 E081 9.0821834 0.0175539367 7.700408e-01 9.113104e-01 8 102345396 102345545 150 - 0.987 1.017 0.110
ENSG00000104517 E082 0.3808443 0.0290846845 1.013003e-01   8 102345896 102346235 340 - 0.000 0.241 11.536
ENSG00000104517 E083 11.7868308 0.0057387183 5.449334e-02 2.325193e-01 8 102346236 102346395 160 - 1.184 1.017 -0.602
ENSG00000104517 E084 10.9026096 0.0031171355 1.731448e-02 1.151914e-01 8 102346903 102347092 190 - 1.170 0.962 -0.756
ENSG00000104517 E085 0.3634051 0.0167486279 5.953962e-01   8 102359652 102360070 419 - 0.171 0.096 -0.968
ENSG00000104517 E086 7.2723512 0.0205209480 1.325739e-01 3.864787e-01 8 102360071 102360190 120 - 0.998 0.826 -0.653
ENSG00000104517 E087 4.7552478 0.0272125260 7.055991e-01 8.804210e-01 8 102360589 102360665 77 - 0.784 0.737 -0.190
ENSG00000104517 E088 3.5271412 0.0043984447 3.859503e-01 6.717388e-01 8 102361125 102361206 82 - 0.709 0.599 -0.470
ENSG00000104517 E089 0.0000000       8 102361207 102361209 3 -      
ENSG00000104517 E090 1.5599954 0.0155293119 5.530699e-02 2.343561e-01 8 102361582 102361626 45 - 0.534 0.241 -1.704
ENSG00000104517 E091 5.5844522 0.0181861738 1.926735e-01 4.724987e-01 8 102412173 102412759 587 - 0.891 0.737 -0.605

Help

Please Click HERE to learn more details about the results from DEXseq.