ENSG00000104522

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000425753 ENSG00000104522 No_inf pgKDN_inf GFUS protein_coding protein_coding 73.04901 68.35305 72.07852 2.03368 1.759369 0.0765528 46.440499 39.260313 53.084685 1.6686588 1.207565 0.4351283 0.63870000 0.577500 0.736700 0.15920 0.03334906 0.03334906 FALSE TRUE
ENST00000527677 ENSG00000104522 No_inf pgKDN_inf GFUS protein_coding retained_intron 73.04901 68.35305 72.07852 2.03368 1.759369 0.0765528 6.267133 5.396740 4.169213 2.0905665 1.093374 -0.3715275 0.08359167 0.076525 0.057075 -0.01945 0.90718343 0.03334906   FALSE
ENST00000532308 ENSG00000104522 No_inf pgKDN_inf GFUS protein_coding retained_intron 73.04901 68.35305 72.07852 2.03368 1.759369 0.0765528 8.084356 9.390144 6.265293 0.8554154 0.976351 -0.5830000 0.11095000 0.137900 0.087250 -0.05065 0.57239799 0.03334906 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104522 E001 0.9958813 0.0120334771 0.1385667430 0.395862116 8 143612618 143612620 3 - 0.171 0.397 1.634
ENSG00000104522 E002 77.1878193 0.0002337411 0.6394105157 0.846636465 8 143612621 143612965 345 - 1.901 1.885 -0.057
ENSG00000104522 E003 4.2980200 0.0031949105 0.5421985757 0.789560115 8 143612966 143613195 230 - 0.686 0.758 0.297
ENSG00000104522 E004 51.6723346 0.0002796382 0.2917100474 0.585124236 8 143613196 143613295 100 - 1.743 1.699 -0.149
ENSG00000104522 E005 2.9420357 0.0094660006 0.9284098240 0.978769238 8 143613296 143613391 96 - 0.590 0.601 0.049
ENSG00000104522 E006 22.7656716 0.0273319709 0.9328497654 0.980593766 8 143613524 143613528 5 - 1.369 1.383 0.049
ENSG00000104522 E007 40.8873270 0.0095837345 0.8034216773 0.926932170 8 143613529 143613603 75 - 1.615 1.629 0.049
ENSG00000104522 E008 2.9451232 0.0172168992 0.6314949610 0.841923176 8 143613604 143613750 147 - 0.562 0.627 0.290
ENSG00000104522 E009 27.1114043 0.0012553946 0.5131423807 0.770120521 8 143613751 143613769 19 - 1.468 1.430 -0.134
ENSG00000104522 E010 42.6983130 0.0003713817 0.9756615602 0.995748601 8 143613770 143613817 48 - 1.642 1.639 -0.009
ENSG00000104522 E011 45.5987401 0.0025683254 0.6218065702 0.836995492 8 143614164 143614228 65 - 1.681 1.656 -0.083
ENSG00000104522 E012 1.0975199 0.0556367987 0.7955242423 0.922342707 8 143614229 143614319 91 - 0.343 0.300 -0.273
ENSG00000104522 E013 20.9514091 0.0185132014 0.2140317131 0.499182115 8 143614320 143614321 2 - 1.391 1.288 -0.357
ENSG00000104522 E014 31.3479191 0.0122857968 0.3168917978 0.609705329 8 143614322 143614363 42 - 1.543 1.475 -0.233
ENSG00000104522 E015 33.5029579 0.0004668037 0.7621585180 0.907258548 8 143614364 143614404 41 - 1.546 1.530 -0.057
ENSG00000104522 E016 33.5122823 0.0004958333 0.6728915361 0.864471610 8 143614405 143614453 49 - 1.549 1.526 -0.078
ENSG00000104522 E017 12.8631531 0.0020658300 0.0037175145 0.040350257 8 143614454 143614623 170 - 1.006 1.241 0.845
ENSG00000104522 E018 26.4826895 0.0123500153 0.3095370373 0.602866191 8 143614624 143614646 23 - 1.475 1.400 -0.259
ENSG00000104522 E019 25.6035131 0.0046050342 0.1575004416 0.424135572 8 143614647 143614671 25 - 1.468 1.378 -0.310
ENSG00000104522 E020 25.0272507 0.0011311500 0.3590720068 0.648529995 8 143614672 143614697 26 - 1.443 1.387 -0.191
ENSG00000104522 E021 1.3707459 0.0125750955 0.1159578915 0.359119892 8 143614698 143614786 89 - 0.236 0.476 1.464
ENSG00000104522 E022 33.5522127 0.0004264568 0.8538542811 0.948418858 8 143614787 143614820 34 - 1.534 1.542 0.028
ENSG00000104522 E023 35.1422325 0.0064568898 0.9667478066 0.993324117 8 143614821 143614862 42 - 1.558 1.557 -0.002
ENSG00000104522 E024 41.6825337 0.0031200387 0.5339551448 0.784289789 8 143614863 143614915 53 - 1.615 1.644 0.099
ENSG00000104522 E025 0.4882780 0.0158659166 0.9709995810   8 143615886 143615942 57 - 0.171 0.175 0.049
ENSG00000104522 E026 1.3776694 0.0102872030 0.0260993111 0.149399304 8 143615943 143616105 163 - 0.171 0.511 2.219
ENSG00000104522 E027 51.7682321 0.0002866012 0.1674483346 0.438083340 8 143616106 143616220 115 - 1.694 1.748 0.185
ENSG00000104522 E028 1.2332898 0.1507524682 0.6074080696 0.829108851 8 143616221 143616440 220 - 0.293 0.397 0.634
ENSG00000104522 E029 1.5970396 0.0083526657 0.7341144763 0.894409735 8 143616441 143616566 126 - 0.388 0.438 0.271
ENSG00000104522 E030 48.2763675 0.0007959865 0.5082654595 0.766589238 8 143616567 143616723 157 - 1.678 1.706 0.093
ENSG00000104522 E031 2.5210179 0.0057111403 0.0001083662 0.002537831 8 143616724 143617036 313 - 0.171 0.739 3.219
ENSG00000104522 E032 1.3691702 0.0096056262 0.1149599644 0.357413032 8 143617037 143617421 385 - 0.236 0.476 1.464
ENSG00000104522 E033 0.0000000       8 143617422 143617427 6 -      
ENSG00000104522 E034 0.3720642 0.0165950015 0.5614259317   8 143617428 143617473 46 - 0.094 0.175 1.048
ENSG00000104522 E035 14.1421694 0.0018506242 0.2275597745 0.516001108 8 143617474 143617552 79 - 1.131 1.222 0.325
ENSG00000104522 E036 0.8690273 0.0132640258 0.2349010542 0.524060122 8 143617928 143618048 121 - 0.171 0.351 1.371

Help

Please Click HERE to learn more details about the results from DEXseq.