ENSG00000104613

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397977 ENSG00000104613 No_inf pgKDN_inf INTS10 protein_coding protein_coding 38.17708 39.54114 37.43462 2.083997 1.379526 -0.07896092 18.381921 13.085823 23.383552 1.7202489 1.0159391 0.8370042 0.4879167 0.336900 0.629025 0.292125 0.02664656 0.02664656 FALSE TRUE
ENST00000517546 ENSG00000104613 No_inf pgKDN_inf INTS10 protein_coding retained_intron 38.17708 39.54114 37.43462 2.083997 1.379526 -0.07896092 5.721327 6.455809 2.890465 0.8129538 0.7351941 -1.1565466 0.1493667 0.161950 0.078850 -0.083100 0.39786595 0.02664656   FALSE
ENST00000520827 ENSG00000104613 No_inf pgKDN_inf INTS10 protein_coding nonsense_mediated_decay 38.17708 39.54114 37.43462 2.083997 1.379526 -0.07896092 1.563338 4.690015 0.000000 2.2272461 0.0000000 -8.8765215 0.0392000 0.117600 0.000000 -0.117600 0.02891131 0.02664656   FALSE
MSTRG.27349.8 ENSG00000104613 No_inf pgKDN_inf INTS10 protein_coding   38.17708 39.54114 37.43462 2.083997 1.379526 -0.07896092 5.013205 5.966251 3.389920 1.0264114 1.0849526 -0.8137399 0.1305000 0.149875 0.089425 -0.060450 0.64259959 0.02664656 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104613 E001 0.3727544 0.0165930909 0.4875004891   8 19817391 19817415 25 + 0.088 0.185 1.244
ENSG00000104613 E002 0.6101607 0.0211267891 0.7911423604 0.919937737 8 19817416 19817436 21 + 0.224 0.185 -0.341
ENSG00000104613 E003 0.6101607 0.0211267891 0.7911423604 0.919937737 8 19817437 19817438 2 + 0.224 0.185 -0.341
ENSG00000104613 E004 0.9662702 0.3547177105 0.4978421278 0.758427741 8 19817439 19817447 9 + 0.371 0.185 -1.344
ENSG00000104613 E005 1.4554295 0.1727318224 0.4785501368 0.744498914 8 19817448 19817449 2 + 0.447 0.315 -0.757
ENSG00000104613 E006 8.0457753 0.0094641554 0.5883933395 0.817360707 8 19817450 19817580 131 + 0.980 0.927 -0.197
ENSG00000104613 E007 9.9570848 0.0015788895 0.2117491902 0.496780235 8 19817581 19817666 86 + 1.088 0.979 -0.400
ENSG00000104613 E008 0.3532727 0.0157635597 0.1388247633   8 19818194 19818274 81 + 0.224 0.000 -11.678
ENSG00000104613 E009 10.4052292 0.0014318673 0.0223956495 0.136073270 8 19818275 19818342 68 + 1.141 0.941 -0.731
ENSG00000104613 E010 0.3730368 0.0167514223 0.4867981485   8 19818343 19818434 92 + 0.088 0.185 1.244
ENSG00000104613 E011 0.1272623 0.0123362936 0.4561170793   8 19818435 19818473 39 + 0.000 0.103 10.475
ENSG00000104613 E012 0.6167962 0.2386290447 0.5588490192 0.800291698 8 19818474 19818872 399 + 0.161 0.255 0.830
ENSG00000104613 E013 14.8634189 0.0337336640 0.7330994429 0.893891034 8 19819573 19819676 104 + 1.212 1.187 -0.089
ENSG00000104613 E014 22.2924788 0.0180031001 0.7373786827 0.895877650 8 19820379 19820518 140 + 1.379 1.354 -0.088
ENSG00000104613 E015 0.4995438 0.0153650951 0.2465107087   8 19820949 19822438 1490 + 0.088 0.255 1.829
ENSG00000104613 E016 20.9959451 0.0069477971 0.9888223819 1.000000000 8 19822439 19822520 82 + 1.341 1.343 0.009
ENSG00000104613 E017 21.9764603 0.0053671223 0.9205019283 0.975214559 8 19823301 19823387 87 + 1.363 1.359 -0.013
ENSG00000104613 E018 16.1521014 0.0008911872 0.1132922121 0.354015189 8 19823388 19823441 54 + 1.284 1.172 -0.395
ENSG00000104613 E019 0.0000000       8 19823442 19823452 11 +      
ENSG00000104613 E020 14.8580971 0.0029748589 0.5994197584 0.824450951 8 19823873 19823894 22 + 1.218 1.179 -0.137
ENSG00000104613 E021 20.6600650 0.0009358622 0.1631263425 0.431773576 8 19823895 19823981 87 + 1.375 1.287 -0.306
ENSG00000104613 E022 16.3109992 0.0008096570 0.3368880899 0.628840667 8 19823982 19824044 63 + 1.268 1.202 -0.234
ENSG00000104613 E023 1.3578059 0.0305509780 0.2521323023 0.543505339 8 19824045 19824492 448 + 0.279 0.457 1.051
ENSG00000104613 E024 1.2597216 0.0102400368 0.0035213222 0.038898964 8 19824664 19824802 139 + 0.088 0.531 3.414
ENSG00000104613 E025 12.5385190 0.0011518659 0.3972551605 0.681475124 8 19824803 19824837 35 + 1.161 1.095 -0.237
ENSG00000104613 E026 25.1582970 0.0005635767 0.0650394400 0.256876284 8 19824838 19824972 135 + 1.464 1.359 -0.364
ENSG00000104613 E027 25.6737035 0.0006802362 0.1294753391 0.381716570 8 19826426 19826559 134 + 1.464 1.379 -0.296
ENSG00000104613 E028 27.4281625 0.0008886113 0.1720165699 0.444731398 8 19830406 19830518 113 + 1.414 1.493 0.270
ENSG00000104613 E029 15.2102165 0.0014068612 0.1048059351 0.338458973 8 19830519 19830559 41 + 1.148 1.269 0.430
ENSG00000104613 E030 20.0737061 0.0009370995 0.2235846595 0.511167473 8 19832028 19832100 73 + 1.358 1.281 -0.268
ENSG00000104613 E031 10.8996834 0.0014907165 0.0280566586 0.156517152 8 19832101 19832110 10 + 1.154 0.966 -0.685
ENSG00000104613 E032 32.3655733 0.0005770889 0.0771729043 0.284152272 8 19833169 19833321 153 + 1.563 1.474 -0.305
ENSG00000104613 E033 8.6697028 0.0020889116 0.8876341869 0.962400736 8 19837052 19837052 1 + 0.990 0.979 -0.041
ENSG00000104613 E034 12.9100727 0.0135212850 0.4182571789 0.697901887 8 19837053 19837080 28 + 1.175 1.104 -0.251
ENSG00000104613 E035 18.2698978 0.0007777350 0.3338113492 0.625782180 8 19837081 19837160 80 + 1.313 1.250 -0.222
ENSG00000104613 E036 0.7332058 0.0144313033 0.8424666499 0.943569646 8 19837161 19837517 357 + 0.224 0.255 0.244
ENSG00000104613 E037 0.8524383 0.0171168022 0.8748293192 0.957156635 8 19841827 19841955 129 + 0.279 0.255 -0.171
ENSG00000104613 E038 12.4925132 0.0011481247 0.4087392014 0.690977310 8 19842848 19842898 51 + 1.096 1.164 0.244
ENSG00000104613 E039 9.5472707 0.0016428218 0.6218373027 0.836995492 8 19842899 19842927 29 + 1.000 1.046 0.170
ENSG00000104613 E040 15.2429941 0.0013028918 0.0473270785 0.213726756 8 19844076 19844127 52 + 1.133 1.281 0.524
ENSG00000104613 E041 24.1055868 0.0005917958 0.3437502617 0.635077814 8 19844128 19844238 111 + 1.371 1.429 0.200
ENSG00000104613 E042 1.2053990 0.0102377116 0.3098460358 0.603119536 8 19845423 19845696 274 + 0.411 0.255 -0.978
ENSG00000104613 E043 0.2363338 0.0156920956 0.3041169112   8 19845697 19845703 7 + 0.161 0.000 -11.093
ENSG00000104613 E044 21.6844754 0.0007437925 0.1862021865 0.464055669 8 19845704 19845797 94 + 1.313 1.397 0.293
ENSG00000104613 E045 3.2470402 0.0044245243 0.0014015527 0.019415939 8 19845798 19845914 117 + 0.371 0.801 1.981
ENSG00000104613 E046 3.8198861 0.0127411218 0.1926912205 0.472498672 8 19847394 19847558 165 + 0.594 0.763 0.713
ENSG00000104613 E047 10.4015322 0.0053954529 0.0005665019 0.009629282 8 19848763 19849161 399 + 0.876 1.194 1.167
ENSG00000104613 E048 4.3222284 0.0033119432 0.0462212991 0.210818787 8 19849162 19849239 78 + 0.594 0.836 1.003
ENSG00000104613 E049 52.5606506 0.0053799990 0.0050829259 0.050246064 8 19851649 19852083 435 + 1.658 1.794 0.460

Help

Please Click HERE to learn more details about the results from DEXseq.