ENSG00000104691

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265616 ENSG00000104691 No_inf pgKDN_inf UBXN8 protein_coding protein_coding 15.47477 12.91892 17.45464 0.8595354 0.4805375 0.4338354 10.1171670 5.197292 14.159749 0.6491612 0.6586136 1.4442090 0.6386667 0.411125 0.814275 0.403150 0.01712296 0.01712296 FALSE TRUE
ENST00000380154 ENSG00000104691 No_inf pgKDN_inf UBXN8 protein_coding nonsense_mediated_decay 15.47477 12.91892 17.45464 0.8595354 0.4805375 0.4338354 4.2207602 5.909137 3.049243 0.8312535 0.8572667 -0.9522123 0.2846000 0.451575 0.172475 -0.279100 0.12760246 0.01712296 FALSE TRUE
ENST00000620706 ENSG00000104691 No_inf pgKDN_inf UBXN8 protein_coding protein_coding_CDS_not_defined 15.47477 12.91892 17.45464 0.8595354 0.4805375 0.4338354 0.6955875 1.213998 0.000000 0.5495544 0.0000000 -6.9354576 0.0475000 0.091175 0.000000 -0.091175 0.07017017 0.01712296   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104691 E001 0.0000000       8 30729131 30729345 215 +      
ENSG00000104691 E002 0.0000000       8 30731529 30732370 842 +      
ENSG00000104691 E003 0.0000000       8 30732619 30733215 597 +      
ENSG00000104691 E004 0.0000000       8 30733216 30733308 93 +      
ENSG00000104691 E005 0.0000000       8 30733847 30734324 478 +      
ENSG00000104691 E006 0.0000000       8 30744164 30744173 10 +      
ENSG00000104691 E007 0.6071071 0.0148704767 0.687770516 0.87125553 8 30744174 30744188 15 + 0.235 0.176 -0.519
ENSG00000104691 E008 0.6071071 0.0148704767 0.687770516 0.87125553 8 30744189 30744189 1 + 0.235 0.176 -0.519
ENSG00000104691 E009 5.6168965 0.0070310350 0.653820991 0.85465728 8 30744190 30744277 88 + 0.844 0.796 -0.186
ENSG00000104691 E010 2.7360791 0.0058819505 0.024520979 0.14376720 8 30744278 30744327 50 + 0.387 0.700 1.481
ENSG00000104691 E011 4.1163556 0.0036870156 0.001702106 0.02253901 8 30744328 30744460 133 + 0.465 0.861 1.709
ENSG00000104691 E012 3.9313980 0.0668314692 0.698804754 0.87727144 8 30751396 30751396 1 + 0.662 0.721 0.246
ENSG00000104691 E013 10.2896570 0.0013442494 0.850464824 0.94698205 8 30751397 30751506 110 + 1.043 1.061 0.065
ENSG00000104691 E014 5.0167827 0.0045246110 0.976057180 0.99600110 8 30751507 30751518 12 + 0.780 0.779 -0.005
ENSG00000104691 E015 11.0228316 0.0021080428 0.848518875 0.94635876 8 30753035 30753105 71 + 1.071 1.089 0.065
ENSG00000104691 E016 17.3697968 0.0008005619 0.919244928 0.97468950 8 30754665 30754749 85 + 1.266 1.262 -0.016
ENSG00000104691 E017 11.3846300 0.0013075611 0.925418277 0.97756447 8 30754750 30754787 38 + 1.088 1.098 0.034
ENSG00000104691 E018 1.5060002 0.1275954765 0.032345835 0.17024888 8 30756119 30756283 165 + 0.170 0.545 2.387
ENSG00000104691 E019 17.1475553 0.0008052165 0.671027026 0.86344201 8 30756765 30756887 123 + 1.243 1.274 0.107
ENSG00000104691 E020 8.2075590 0.0017956467 0.770891342 0.91163594 8 30760888 30760929 42 + 0.949 0.978 0.109
ENSG00000104691 E021 0.0000000       8 30763146 30763272 127 +      
ENSG00000104691 E022 10.5377411 0.0014908487 0.679691417 0.86767086 8 30763273 30763347 75 + 1.043 1.080 0.133
ENSG00000104691 E023 48.2328050 0.0003559154 0.004142927 0.04355645 8 30766227 30767006 780 + 1.741 1.639 -0.345

Help

Please Click HERE to learn more details about the results from DEXseq.