ENSG00000104852

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000221448 ENSG00000104852 No_inf pgKDN_inf SNRNP70 protein_coding protein_coding 158.4567 167.3339 135.8492 6.217951 2.991746 -0.3007033 30.32688 35.50702 22.301812 3.2310472 1.376015 -0.6707028 0.19040833 0.212500 0.164950 -0.047550 6.214317e-01 6.138658e-06 FALSE TRUE
ENST00000401730 ENSG00000104852 No_inf pgKDN_inf SNRNP70 protein_coding nonsense_mediated_decay 158.4567 167.3339 135.8492 6.217951 2.991746 -0.3007033 10.64928 19.53697 2.846369 1.7596018 1.869682 -2.7746909 0.06468333 0.118025 0.020175 -0.097850 7.294297e-02 6.138658e-06 FALSE TRUE
ENST00000597936 ENSG00000104852 No_inf pgKDN_inf SNRNP70 protein_coding retained_intron 158.4567 167.3339 135.8492 6.217951 2.991746 -0.3007033 25.77638 20.38257 18.196745 6.8774215 3.481878 -0.1635705 0.15795833 0.118475 0.132825 0.014350 8.817412e-01 6.138658e-06 FALSE FALSE
ENST00000598441 ENSG00000104852 No_inf pgKDN_inf SNRNP70 protein_coding protein_coding 158.4567 167.3339 135.8492 6.217951 2.991746 -0.3007033 42.84584 19.48072 57.840121 5.2171388 2.139373 1.5695325 0.28203333 0.119375 0.427000 0.307625 6.138658e-06 6.138658e-06 FALSE TRUE
ENST00000599687 ENSG00000104852 No_inf pgKDN_inf SNRNP70 protein_coding retained_intron 158.4567 167.3339 135.8492 6.217951 2.991746 -0.3007033 17.60408 21.14180 13.533583 0.4606825 1.281264 -0.6431711 0.11060833 0.126650 0.099950 -0.026700 7.266989e-01 6.138658e-06 FALSE TRUE
MSTRG.15443.1 ENSG00000104852 No_inf pgKDN_inf SNRNP70 protein_coding   158.4567 167.3339 135.8492 6.217951 2.991746 -0.3007033 23.57963 39.76232 12.590666 1.2310822 1.368907 -1.6582646 0.14634167 0.238975 0.093375 -0.145600 2.756229e-04 6.138658e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104852 E001 1.2322490 1.437796e-02 8.174622e-01 9.336088e-01 19 49085379 49085418 40 + 0.360 0.325 -0.216
ENSG00000104852 E002 1.8512512 1.056068e-02 7.777968e-01 9.147937e-01 19 49085419 49085422 4 + 0.468 0.426 -0.216
ENSG00000104852 E003 5.5189704 1.270235e-02 1.090359e-01 3.466804e-01 19 49085423 49085450 28 + 0.909 0.721 -0.737
ENSG00000104852 E004 5.7736524 2.756186e-03 1.500172e-01 4.124821e-01 19 49085451 49085452 2 + 0.909 0.751 -0.617
ENSG00000104852 E005 39.6505194 1.558411e-03 5.727691e-01 8.085570e-01 19 49085453 49085494 42 + 1.607 1.579 -0.095
ENSG00000104852 E006 120.0002905 2.083943e-03 3.308466e-02 1.727997e-01 19 49085495 49085636 142 + 2.106 2.036 -0.234
ENSG00000104852 E007 106.8687965 1.506694e-04 1.375344e-04 3.083035e-03 19 49086405 49086479 75 + 2.081 1.970 -0.373
ENSG00000104852 E008 88.8929247 1.861796e-04 6.722360e-04 1.099344e-02 19 49086480 49086523 44 + 2.001 1.892 -0.366
ENSG00000104852 E009 76.2247749 1.398514e-03 2.913752e-03 3.380826e-02 19 49086524 49086561 38 + 1.936 1.825 -0.374
ENSG00000104852 E010 0.5004251 4.701897e-01 9.044080e-01 9.692666e-01 19 49087634 49087777 144 + 0.122 0.192 0.784
ENSG00000104852 E011 90.5468458 1.821187e-04 2.571513e-03 3.073848e-02 19 49090291 49090353 63 + 2.001 1.905 -0.322
ENSG00000104852 E012 104.7754459 2.509643e-04 2.507962e-06 1.030194e-04 19 49090466 49090520 55 + 2.089 1.950 -0.468
ENSG00000104852 E013 0.3516386 2.177748e-02 3.337900e-02   19 49090521 49090639 119 + 0.294 0.000 -10.995
ENSG00000104852 E014 113.7954020 1.666284e-04 2.478914e-08 1.640463e-06 19 49098427 49098491 65 + 2.135 1.978 -0.526
ENSG00000104852 E015 97.5169340 1.774231e-04 2.327907e-06 9.665382e-05 19 49098642 49098704 63 + 2.061 1.917 -0.484
ENSG00000104852 E016 112.2155914 1.464810e-04 1.043136e-05 3.538396e-04 19 49101390 49101471 82 + 2.110 1.985 -0.419
ENSG00000104852 E017 12.8179249 2.026840e-03 8.190608e-02 2.944622e-01 19 49101472 49101668 197 + 1.016 1.168 0.550
ENSG00000104852 E018 36.9644779 3.994230e-04 4.304638e-12 5.193878e-10 19 49102114 49102173 60 + 1.258 1.662 1.390
ENSG00000104852 E019 17.2363102 1.390717e-02 2.768921e-03 3.250033e-02 19 49102174 49102185 12 + 1.042 1.319 0.986
ENSG00000104852 E020 64.5175415 2.300171e-04 4.708281e-14 7.276115e-12 19 49102186 49102410 225 + 1.559 1.883 1.099
ENSG00000104852 E021 274.5234455 7.818111e-05 1.128286e-71 4.056867e-68 19 49102411 49103587 1177 + 2.147 2.515 1.230
ENSG00000104852 E022 149.2576774 1.117835e-03 6.741565e-34 4.784205e-31 19 49103588 49104633 1046 + 1.869 2.256 1.294
ENSG00000104852 E023 117.8415009 3.428698e-03 2.616812e-04 5.209862e-03 19 49104634 49104735 102 + 2.135 2.004 -0.438
ENSG00000104852 E024 121.2658005 1.395105e-04 1.152650e-03 1.670875e-02 19 49107625 49107712 88 + 2.122 2.033 -0.298
ENSG00000104852 E025 49.2145976 3.538920e-04 3.714939e-03 4.034636e-02 19 49107795 49107821 27 + 1.758 1.632 -0.424
ENSG00000104852 E026 336.8853472 9.818029e-05 7.594715e-04 1.214029e-02 19 49107822 49108606 785 + 2.542 2.489 -0.177

Help

Please Click HERE to learn more details about the results from DEXseq.