ENSG00000104853

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337392 ENSG00000104853 No_inf pgKDN_inf CLPTM1 protein_coding protein_coding 75.9911 56.19517 81.24976 2.42178 1.211738 0.5318384 70.03069 49.70425 77.24161 1.873519 0.7480242 0.6359055 0.9190417 0.88515 0.950975 0.065825 0.007082745 0.007082745 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000104853 E001 0.0000000       19 44954585 44954590 6 +      
ENSG00000104853 E002 0.3815350 0.0317580772 0.06191502   19 44954591 44954701 111 + 0.000 0.265 11.197
ENSG00000104853 E003 0.3815350 0.0317580772 0.06191502   19 44954702 44955085 384 + 0.000 0.265 13.430
ENSG00000104853 E004 0.8441312 0.0133792031 0.42939383 0.70762116 19 44955380 44955380 1 + 0.315 0.194 -0.925
ENSG00000104853 E005 16.6677309 0.0027553477 0.72436534 0.88928162 19 44955381 44955467 87 + 1.257 1.231 -0.092
ENSG00000104853 E006 0.0000000       19 44955558 44955840 283 +      
ENSG00000104853 E007 32.4726133 0.0028591992 0.02266257 0.13705632 19 44961963 44962075 113 + 1.576 1.447 -0.445
ENSG00000104853 E008 45.1168441 0.0040287332 0.02306604 0.13856580 19 44973087 44973210 124 + 1.711 1.593 -0.399
ENSG00000104853 E009 46.3342448 0.0041907902 0.34551575 0.63650722 19 44974439 44974546 108 + 1.694 1.646 -0.163
ENSG00000104853 E010 30.1123776 0.0005071118 0.86181849 0.95217634 19 44974547 44974597 51 + 1.486 1.496 0.033
ENSG00000104853 E011 47.9984720 0.0003790378 0.82805634 0.93773864 19 44977343 44977460 118 + 1.692 1.683 -0.031
ENSG00000104853 E012 0.8614407 0.0124017740 0.46374153 0.73353135 19 44984287 44984616 330 + 0.215 0.327 0.812
ENSG00000104853 E013 61.5625523 0.0002564655 0.71780136 0.88650726 19 44985218 44985303 86 + 1.788 1.802 0.046
ENSG00000104853 E014 86.8003473 0.0003008931 0.84132516 0.94305428 19 44986455 44986575 121 + 1.938 1.945 0.022
ENSG00000104853 E015 4.9304713 0.0100674766 0.04047324 0.19510938 19 44986576 44986903 328 + 0.645 0.889 0.982
ENSG00000104853 E016 1.9933973 0.0135168864 0.01176699 0.08945723 19 44986904 44987178 275 + 0.268 0.640 1.981
ENSG00000104853 E017 100.0192707 0.0002059660 0.80345626 0.92693217 19 44987179 44987360 182 + 2.005 1.998 -0.025
ENSG00000104853 E018 40.0155003 0.0007043292 0.47986355 0.74544085 19 44987361 44987423 63 + 1.595 1.629 0.114
ENSG00000104853 E019 1.6129599 0.0134742582 0.06338252 0.25333279 19 44987424 44987862 439 + 0.268 0.547 1.567
ENSG00000104853 E020 52.2801413 0.0039915761 0.19990765 0.48172267 19 44988080 44988173 94 + 1.696 1.757 0.208
ENSG00000104853 E021 2.7106455 0.0052871250 0.13887045 0.39626681 19 44989984 44990394 411 + 0.465 0.668 0.927
ENSG00000104853 E022 78.2888763 0.0002965396 0.07403133 0.27722044 19 44990395 44990585 191 + 1.923 1.863 -0.203
ENSG00000104853 E023 68.1726041 0.0002314764 0.44631816 0.72071154 19 44990850 44990945 96 + 1.850 1.822 -0.092
ENSG00000104853 E024 84.0212785 0.0003416051 0.55793931 0.79968448 19 44991238 44991373 136 + 1.919 1.938 0.064
ENSG00000104853 E025 43.5620632 0.0005284953 0.40253194 0.68564166 19 44992233 44992267 35 + 1.629 1.667 0.129
ENSG00000104853 E026 91.9938845 0.0001886392 0.27605861 0.56947580 19 44992268 44992400 133 + 1.951 1.984 0.112
ENSG00000104853 E027 0.4993265 0.0152705341 0.20482102   19 44992553 44992610 58 + 0.084 0.265 1.981
ENSG00000104853 E028 197.4820027 0.0001572956 0.57176833 0.80790442 19 44992611 44993341 731 + 2.290 2.302 0.039

Help

Please Click HERE to learn more details about the results from DEXseq.