ENSG00000105122

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000343625 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding protein_coding 44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 6.882083 0.000000 10.774129 0.0000000 4.1148793 10.0746940 0.18485000 0.000000 0.289050 0.289050 0.003839036 0.003839036 FALSE TRUE
ENST00000599694 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding protein_coding 44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 2.285776 1.940272 3.299595 1.9402722 3.2995950 0.7629792 0.05042500 0.030850 0.077175 0.046325 0.983568631 0.003839036 FALSE TRUE
ENST00000609274 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding protein_coding 44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 3.764351 8.278299 1.262573 0.7869075 0.5075722 -2.7033277 0.07330833 0.141325 0.030600 -0.110725 0.036482986 0.003839036 FALSE TRUE
MSTRG.14684.10 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding   44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 4.106451 6.669305 4.028162 1.5844664 1.9308327 -0.7259992 0.08575833 0.115650 0.098700 -0.016950 0.850125155 0.003839036 FALSE TRUE
MSTRG.14684.5 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding   44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 6.335297 10.170951 3.302051 1.4575882 0.4080783 -1.6200754 0.13533333 0.174225 0.083425 -0.090800 0.240748275 0.003839036 FALSE TRUE
MSTRG.14684.6 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding   44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 4.095617 7.430194 1.620303 0.4216441 0.1222969 -2.1902005 0.08583333 0.128075 0.041800 -0.086275 0.052228322 0.003839036 FALSE TRUE
MSTRG.14684.7 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding   44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 5.747008 9.152979 4.602414 1.5838792 2.6660918 -0.9902949 0.12483333 0.158450 0.121550 -0.036900 0.712849618 0.003839036 FALSE TRUE
MSTRG.14684.8 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding   44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 5.696061 8.105369 2.836123 3.2946706 1.6968666 -1.5116585 0.12442500 0.138775 0.071475 -0.067300 0.809742215 0.003839036 FALSE TRUE
MSTRG.14684.9 ENSG00000105122 No_inf pgKDN_inf RASAL3 protein_coding   44.97122 58.35845 39.281 1.530222 1.978692 -0.5709899 3.446633 2.558368 6.663669 1.6793348 2.3703817 1.3776283 0.07868333 0.044050 0.161575 0.117525 0.568202370 0.003839036 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105122 E001 0.0000000       19 15451624 15451626 3 -      
ENSG00000105122 E002 0.1265070 0.0123210760 1.000000e+00   19 15451627 15451628 2 - 0.000 0.075 7.950
ENSG00000105122 E003 3.0837410 0.0047839544 7.805432e-01 9.153888e-01 19 15451629 15451657 29 - 0.622 0.582 -0.175
ENSG00000105122 E004 68.6544869 0.0035323707 7.795014e-01 9.150054e-01 19 15451658 15451938 281 - 1.817 1.827 0.034
ENSG00000105122 E005 5.5474002 0.0024976904 2.100377e-05 6.410963e-04 19 15451939 15452044 106 - 0.357 0.931 2.562
ENSG00000105122 E006 34.5546609 0.0004122344 9.096106e-03 7.555341e-02 19 15452045 15452108 64 - 1.438 1.576 0.472
ENSG00000105122 E007 23.9796922 0.0155972889 1.322570e-07 7.532364e-06 19 15452109 15452657 549 - 1.024 1.495 1.664
ENSG00000105122 E008 58.0773806 0.0095398251 3.332004e-01 6.252464e-01 19 15452658 15452815 158 - 1.789 1.731 -0.195
ENSG00000105122 E009 106.6879873 0.0001526242 7.079434e-02 2.694306e-01 19 15453107 15453497 391 - 2.047 1.993 -0.182
ENSG00000105122 E010 54.3716904 0.0002637995 9.723507e-02 3.247833e-01 19 15454149 15454267 119 - 1.768 1.698 -0.238
ENSG00000105122 E011 42.8606513 0.0003877478 7.635609e-01 9.078324e-01 19 15454361 15454473 113 - 1.634 1.617 -0.056
ENSG00000105122 E012 40.0197121 0.0003932509 2.272727e-01 5.156370e-01 19 15454474 15454562 89 - 1.557 1.613 0.193
ENSG00000105122 E013 1.1323327 0.0906736140 1.057858e-01 3.404207e-01 19 15454653 15454656 4 - 0.120 0.399 2.240
ENSG00000105122 E014 84.6086904 0.0002307167 5.212611e-01 7.753053e-01 19 15454657 15454893 237 - 1.901 1.920 0.063
ENSG00000105122 E015 33.6127058 0.0004807262 1.577844e-13 2.281487e-11 19 15454894 15456103 1210 - 1.186 1.633 1.549
ENSG00000105122 E016 35.7766852 0.0004171459 4.119164e-01 6.934684e-01 19 15456104 15456164 61 - 1.521 1.561 0.136
ENSG00000105122 E017 40.8875193 0.0003949128 8.488779e-01 9.464293e-01 19 15456165 15456248 84 - 1.611 1.599 -0.039
ENSG00000105122 E018 8.7367283 0.0387294486 6.230748e-02 2.507081e-01 19 15456249 15456375 127 - 0.807 1.040 0.881
ENSG00000105122 E019 5.6256630 0.0596418244 8.971475e-02 3.112089e-01 19 15456376 15456501 126 - 0.622 0.880 1.048
ENSG00000105122 E020 41.5412333 0.0021755862 1.141708e-02 8.779140e-02 19 15456502 15456646 145 - 1.688 1.561 -0.434
ENSG00000105122 E021 0.7630396 0.1540675250 6.953370e-02 2.665788e-01 19 15456647 15456679 33 - 0.000 0.328 12.284
ENSG00000105122 E022 0.6175864 0.0143621426 9.002998e-01 9.676132e-01 19 15456778 15456891 114 - 0.214 0.194 -0.175
ENSG00000105122 E023 27.1162706 0.0053800806 7.279174e-03 6.481674e-02 19 15457292 15457468 177 - 1.533 1.362 -0.590
ENSG00000105122 E024 53.1769684 0.0037065064 2.432698e-02 1.430029e-01 19 15457469 15457834 366 - 1.782 1.673 -0.371
ENSG00000105122 E025 6.5232927 0.0540817096 1.455927e-02 1.029553e-01 19 15457835 15457921 87 - 0.587 0.958 1.496
ENSG00000105122 E026 26.6528305 0.0010273838 2.113938e-07 1.143562e-05 19 15457922 15458327 406 - 1.177 1.516 1.181
ENSG00000105122 E027 31.5074212 0.0207586493 9.788526e-03 7.920996e-02 19 15458328 15458426 99 - 1.614 1.409 -0.705
ENSG00000105122 E028 30.7499992 0.0130399062 1.040129e-01 3.369996e-01 19 15458529 15458655 127 - 1.553 1.440 -0.389
ENSG00000105122 E029 13.3777203 0.0076240977 6.030661e-02 2.464410e-01 19 15460203 15460220 18 - 1.237 1.076 -0.575
ENSG00000105122 E030 15.1654408 0.0168796000 5.017304e-01 7.615773e-01 19 15460221 15460258 38 - 1.229 1.168 -0.214
ENSG00000105122 E031 18.0980540 0.0017509411 1.735076e-01 4.467872e-01 19 15461060 15461121 62 - 1.324 1.225 -0.345
ENSG00000105122 E032 16.7396708 0.0008497348 1.997614e-01 4.815581e-01 19 15461218 15461296 79 - 1.289 1.195 -0.333
ENSG00000105122 E033 0.4985061 0.0286880354 6.339090e-01   19 15461297 15461317 21 - 0.120 0.194 0.825
ENSG00000105122 E034 16.5411493 0.0008375088 5.863068e-01 8.165636e-01 19 15461471 15461607 137 - 1.252 1.210 -0.148
ENSG00000105122 E035 27.5733197 0.0088646111 1.018407e-01 3.333540e-01 19 15464031 15464377 347 - 1.508 1.393 -0.398
ENSG00000105122 E036 1.2495246 0.0101438603 2.415980e-01 5.313521e-01 19 15464505 15464566 62 - 0.214 0.399 1.240

Help

Please Click HERE to learn more details about the results from DEXseq.