ENSG00000105197

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000594583 ENSG00000105197 No_inf pgKDN_inf TIMM50 protein_coding protein_coding 67.75811 44.18208 80.31802 2.887703 2.653725 0.8621153 23.3634128 14.345266 27.43928 1.790687 2.745829 0.9351881 0.3406917 0.322975 0.339975 0.017000 0.95788233 0.02431241 FALSE FALSE
ENST00000597666 ENSG00000105197 No_inf pgKDN_inf TIMM50 protein_coding protein_coding 67.75811 44.18208 80.31802 2.887703 2.653725 0.8621153 0.7411113 2.223334 0.00000 1.691289 0.000000 -7.8030552 0.0169500 0.050850 0.000000 -0.050850 0.40250731 0.02431241 FALSE FALSE
ENST00000599794 ENSG00000105197 No_inf pgKDN_inf TIMM50 protein_coding protein_coding 67.75811 44.18208 80.31802 2.887703 2.653725 0.8621153 11.8685601 6.245208 13.93400 2.111449 2.228508 1.1565145 0.1705083 0.142100 0.173000 0.030900 0.84987466 0.02431241 FALSE TRUE
ENST00000601403 ENSG00000105197 No_inf pgKDN_inf TIMM50 protein_coding protein_coding 67.75811 44.18208 80.31802 2.887703 2.653725 0.8621153 8.7776045 1.273173 12.74946 1.273173 1.976247 3.3137798 0.1140583 0.024600 0.160925 0.136325 0.02431241 0.02431241 FALSE TRUE
ENST00000602265 ENSG00000105197 No_inf pgKDN_inf TIMM50 protein_coding nonsense_mediated_decay 67.75811 44.18208 80.31802 2.887703 2.653725 0.8621153 13.0817749 9.372910 17.92733 2.224431 1.399773 0.9348576 0.1983583 0.222175 0.222575 0.000400 0.96432673 0.02431241 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105197 E001 0.0000000       19 39480412 39480483 72 +      
ENSG00000105197 E002 0.3722815 0.0165507542 0.3544204416   19 39480484 39480837 354 + 0.079 0.205 1.608
ENSG00000105197 E003 0.4987885 0.0231956202 0.1588667346   19 39480838 39480840 3 + 0.079 0.280 2.193
ENSG00000105197 E004 0.9802701 0.0141660058 0.5566658689 0.79885100 19 39480841 39480845 5 + 0.254 0.344 0.608
ENSG00000105197 E005 1.3342345 0.0096129877 0.8281886123 0.93774495 19 39480846 39480849 4 + 0.378 0.344 -0.199
ENSG00000105197 E006 1.3342345 0.0096129877 0.8281886123 0.93774495 19 39480850 39480852 3 + 0.378 0.344 -0.199
ENSG00000105197 E007 1.3342345 0.0096129877 0.8281886123 0.93774495 19 39480853 39480855 3 + 0.378 0.344 -0.199
ENSG00000105197 E008 1.7073363 0.0082223864 0.8048755216 0.92776568 19 39480856 39480857 2 + 0.413 0.449 0.193
ENSG00000105197 E009 5.9003695 0.0023539036 0.0571827239 0.23901636 19 39480858 39480881 24 + 0.910 0.693 -0.861
ENSG00000105197 E010 9.5472904 0.0014014477 0.1454477467 0.40595005 19 39480882 39480927 46 + 1.068 0.932 -0.503
ENSG00000105197 E011 11.2120147 0.0016486754 0.0350780509 0.17924203 19 39480928 39480961 34 + 1.149 0.962 -0.681
ENSG00000105197 E012 0.0000000       19 39481225 39481316 92 +      
ENSG00000105197 E013 27.6842477 0.0187068487 0.0822937868 0.29538372 19 39481883 39482033 151 + 1.501 1.369 -0.459
ENSG00000105197 E014 19.7836570 0.0007614404 0.5733495827 0.80876256 19 39482885 39482916 32 + 1.327 1.289 -0.134
ENSG00000105197 E015 0.1186381 0.0118497387 0.8392337712   19 39482917 39482963 47 + 0.079 0.000 -9.664
ENSG00000105197 E016 0.9810290 0.0167689484 0.5564471419 0.79872838 19 39482964 39483134 171 + 0.254 0.344 0.608
ENSG00000105197 E017 17.0032761 0.0008938440 0.6796703730 0.86767086 19 39483135 39483156 22 + 1.261 1.231 -0.107
ENSG00000105197 E018 1.8553729 0.3001909707 0.2395770180 0.52867505 19 39483157 39483545 389 + 0.299 0.604 1.607
ENSG00000105197 E019 0.3703650 0.0166786504 0.3540104699   19 39485039 39485151 113 + 0.079 0.205 1.608
ENSG00000105197 E020 0.8708214 0.0129839267 0.0912304139 0.31378141 19 39485152 39485263 112 + 0.145 0.400 1.930
ENSG00000105197 E021 2.7314446 0.0063083520 0.0075562681 0.06651539 19 39485264 39485543 280 + 0.378 0.743 1.708
ENSG00000105197 E022 29.1659519 0.0056162511 0.8913930513 0.96384108 19 39485544 39485590 47 + 1.476 1.468 -0.027
ENSG00000105197 E023 21.7394408 0.0109051936 0.7763383168 0.91413093 19 39485591 39485602 12 + 1.358 1.339 -0.065
ENSG00000105197 E024 0.6253605 0.1628311653 0.1039132305 0.33686699 19 39485603 39485687 85 + 0.079 0.344 2.607
ENSG00000105197 E025 37.9403554 0.0004485074 0.2403368961 0.52952858 19 39485688 39485807 120 + 1.607 1.550 -0.196
ENSG00000105197 E026 1.0973052 0.0112672669 0.7689297976 0.91062684 19 39485808 39486186 379 + 0.299 0.344 0.286
ENSG00000105197 E027 34.2270860 0.0007336454 0.5751120679 0.80974506 19 39486187 39486291 105 + 1.553 1.523 -0.102
ENSG00000105197 E028 33.3754862 0.0005520081 0.5478242526 0.79319069 19 39486397 39486495 99 + 1.543 1.511 -0.109
ENSG00000105197 E029 0.1186381 0.0118497387 0.8392337712   19 39488006 39488060 55 + 0.079 0.000 -9.664
ENSG00000105197 E030 25.6444786 0.0005363017 0.0454783634 0.20857398 19 39488061 39488113 53 + 1.465 1.345 -0.412
ENSG00000105197 E031 36.8680419 0.0091833019 0.2774417450 0.57073679 19 39488114 39488217 104 + 1.598 1.531 -0.231
ENSG00000105197 E032 33.8986674 0.0091829420 0.9036419007 0.96904248 19 39488539 39488645 107 + 1.540 1.531 -0.033
ENSG00000105197 E033 39.2712030 0.0022218957 0.0839532401 0.29899195 19 39489719 39490418 700 + 1.562 1.646 0.284
ENSG00000105197 E034 9.3341018 0.0015964753 0.0115780743 0.08853706 19 39490419 39491511 1093 + 0.900 1.127 0.836
ENSG00000105197 E035 5.7348796 0.0033491312 0.4788742421 0.74480642 19 39491512 39491896 385 + 0.789 0.866 0.300
ENSG00000105197 E036 10.4741218 0.0204115168 0.0023672617 0.02892512 19 39491897 39492416 520 + 0.900 1.207 1.122
ENSG00000105197 E037 6.6741223 0.0039815426 0.0006512428 0.01071838 19 39492417 39492768 352 + 0.696 1.052 1.374
ENSG00000105197 E038 9.9605250 0.0013356663 0.0037272468 0.04041881 19 39492769 39493294 526 + 0.910 1.164 0.930
ENSG00000105197 E039 5.0209990 0.0030671028 0.2353957577 0.52470800 19 39493295 39493785 491 + 0.713 0.848 0.538

Help

Please Click HERE to learn more details about the results from DEXseq.