ENSG00000105339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000424248 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding protein_coding 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 11.384186 12.31000 11.305607 4.2511869 4.7133997 -0.1226887 0.08964167 0.055500 0.114075 0.058575 0.899772777 0.001933838 FALSE TRUE
ENST00000517985 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding protein_coding 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 7.965047 11.76609 3.177784 3.3194364 1.8735576 -1.8852347 0.05468333 0.053275 0.030450 -0.022825 0.599845625 0.001933838 FALSE TRUE
ENST00000518806 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding protein_coding_CDS_not_defined 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 10.940006 20.06373 5.092716 1.6829982 0.4097275 -1.9759716 0.07325833 0.093250 0.054625 -0.038625 0.312863835 0.001933838 FALSE FALSE
ENST00000519811 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding protein_coding 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 26.917126 26.92872 29.735671 3.2130357 1.1839645 0.1429986 0.22590833 0.127200 0.324725 0.197525 0.001933838 0.001933838 FALSE TRUE
ENST00000521835 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding retained_intron 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 9.288923 18.53797 4.025850 0.9762688 1.3597759 -2.2003166 0.05956667 0.086775 0.042300 -0.044475 0.537220041 0.001933838 FALSE TRUE
ENST00000523015 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding retained_intron 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 10.040073 23.81057 2.275373 5.8314267 2.2753733 -3.3817062 0.05645833 0.108250 0.022850 -0.085400 0.025182860 0.001933838 FALSE FALSE
ENST00000523308 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding protein_coding 138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 7.863180 15.32178 3.307193 1.0874389 0.7028502 -2.2084901 0.05095833 0.071300 0.035125 -0.036175 0.261707015 0.001933838 FALSE TRUE
MSTRG.28290.16 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding   138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 10.786563 18.52160 6.943906 0.7595811 0.4946619 -1.4140918 0.07566667 0.086225 0.076100 -0.010125 0.868628671 0.001933838 TRUE TRUE
MSTRG.28290.19 ENSG00000105339 No_inf pgKDN_inf DENND3 protein_coding   138.9026 215.6886 93.56724 8.467678 6.399837 -1.204788 8.033121 14.15821 4.132829 0.3919566 0.4292090 -1.7739690 0.05485833 0.065925 0.044375 -0.021550 0.590343530 0.001933838 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105339 E001 0.3533378 1.580148e-02 2.422701e-02   8 141117278 141117364 87 + 0.309 0.000 -11.821
ENSG00000105339 E002 0.7448190 4.061427e-02 9.985385e-01 1.000000e+00 8 141128589 141128611 23 + 0.229 0.228 0.000
ENSG00000105339 E003 1.4799413 8.284611e-02 5.823673e-01 8.139126e-01 8 141128612 141128620 9 + 0.436 0.345 -0.515
ENSG00000105339 E004 1.5985794 6.287016e-02 3.786999e-01 6.656064e-01 8 141128621 141128627 7 + 0.488 0.345 -0.778
ENSG00000105339 E005 3.6668033 3.852028e-03 2.681134e-02 1.519591e-01 8 141128628 141128648 21 + 0.815 0.534 -1.193
ENSG00000105339 E006 8.5444589 1.601476e-03 3.923155e-04 7.179893e-03 8 141128649 141128674 26 + 1.151 0.815 -1.248
ENSG00000105339 E007 22.0495005 1.388753e-03 1.497664e-05 4.836827e-04 8 141128675 141128778 104 + 1.503 1.224 -0.968
ENSG00000105339 E008 17.2223255 6.996388e-03 2.380406e-02 1.412167e-01 8 141128779 141128809 31 + 1.345 1.167 -0.627
ENSG00000105339 E009 20.2539156 2.733896e-02 1.618523e-02 1.105271e-01 8 141136509 141136557 49 + 1.442 1.210 -0.807
ENSG00000105339 E010 28.4613881 8.472226e-04 1.092003e-02 8.518383e-02 8 141136558 141136625 68 + 1.534 1.387 -0.508
ENSG00000105339 E011 43.2010964 5.003467e-03 1.932110e-03 2.490593e-02 8 141136626 141136791 166 + 1.724 1.554 -0.578
ENSG00000105339 E012 2.2216710 6.315189e-03 6.283278e-01 8.403568e-01 8 141137889 141138021 133 + 0.534 0.463 -0.348
ENSG00000105339 E013 39.9249141 6.190621e-03 3.294782e-04 6.274744e-03 8 141138022 141138137 116 + 1.712 1.505 -0.706
ENSG00000105339 E014 52.7104985 8.999849e-03 3.412792e-06 1.348466e-04 8 141141203 141141324 122 + 1.861 1.598 -0.893
ENSG00000105339 E015 1.3537798 1.003534e-02 4.125563e-01 6.937552e-01 8 141141325 141141505 181 + 0.436 0.309 -0.737
ENSG00000105339 E016 53.5586088 2.587744e-04 9.572111e-06 3.279938e-04 8 141141506 141142299 794 + 1.556 1.762 0.699
ENSG00000105339 E017 56.1749477 1.138721e-03 8.262215e-06 2.898353e-04 8 141142300 141142756 457 + 1.572 1.783 0.716
ENSG00000105339 E018 113.5464334 2.386602e-03 3.182049e-12 3.900469e-10 8 141142757 141143913 1157 + 1.827 2.097 0.908
ENSG00000105339 E019 34.9271963 2.595804e-02 9.871708e-04 1.485549e-02 8 141143914 141144147 234 + 1.302 1.600 1.026
ENSG00000105339 E020 70.2266467 4.164303e-04 7.567539e-02 2.810831e-01 8 141144148 141144259 112 + 1.867 1.799 -0.231
ENSG00000105339 E021 3.2108784 7.076314e-03 5.938245e-01 8.211555e-01 8 141150286 141150348 63 + 0.650 0.576 -0.322
ENSG00000105339 E022 71.8259873 2.301718e-04 5.146554e-01 7.711405e-01 8 141150834 141150953 120 + 1.849 1.823 -0.085
ENSG00000105339 E023 86.5408964 8.872154e-04 4.659246e-02 2.118103e-01 8 141151619 141151837 219 + 1.959 1.887 -0.241
ENSG00000105339 E024 33.1674781 4.200459e-04 4.013259e-01 6.845170e-01 8 141155849 141155893 45 + 1.534 1.488 -0.159
ENSG00000105339 E025 39.9899847 5.613027e-04 3.050061e-02 1.643377e-01 8 141155894 141155970 77 + 1.653 1.545 -0.367
ENSG00000105339 E026 2.0949457 6.565345e-03 5.069473e-01 7.656123e-01 8 141157395 141158287 893 + 0.534 0.436 -0.486
ENSG00000105339 E027 45.1631853 6.482248e-03 5.337919e-02 2.299724e-01 8 141160632 141160787 156 + 1.706 1.596 -0.375
ENSG00000105339 E028 43.7671812 6.318867e-03 2.734447e-01 5.671858e-01 8 141163333 141163429 97 + 1.663 1.600 -0.215
ENSG00000105339 E029 63.4730282 6.833932e-04 2.206321e-02 1.349311e-01 8 141165186 141165289 104 + 1.840 1.747 -0.314
ENSG00000105339 E030 103.8019727 8.766976e-04 8.036475e-04 1.265147e-02 8 141166190 141166389 200 + 2.062 1.952 -0.369
ENSG00000105339 E031 212.2734718 8.699684e-05 6.048594e-08 3.707101e-06 8 141168004 141168521 518 + 2.374 2.258 -0.387
ENSG00000105339 E032 24.3441899 1.143877e-02 2.182010e-01 5.046506e-01 8 141168522 141168525 4 + 1.436 1.341 -0.330
ENSG00000105339 E033 19.2768132 8.832891e-04 1.521500e-04 3.337152e-03 8 141173172 141173504 333 + 1.056 1.351 1.047
ENSG00000105339 E034 18.4200668 8.683323e-03 1.395658e-01 3.972330e-01 8 141173505 141173741 237 + 1.172 1.294 0.433
ENSG00000105339 E035 28.7256067 1.763505e-03 4.590676e-01 7.307848e-01 8 141175200 141175204 5 + 1.473 1.428 -0.156
ENSG00000105339 E036 132.5483789 1.597628e-04 1.406790e-02 1.004153e-01 8 141175205 141175459 255 + 2.140 2.072 -0.229
ENSG00000105339 E037 110.0791459 1.506680e-04 5.146234e-21 1.508462e-18 8 141175460 141176590 1131 + 1.772 2.094 1.081
ENSG00000105339 E038 115.1420629 7.044456e-04 2.697028e-03 3.185753e-02 8 141176591 141176761 171 + 2.095 2.002 -0.313
ENSG00000105339 E039 65.8266892 2.739508e-03 8.645610e-13 1.148503e-10 8 141177087 141178066 980 + 1.521 1.879 1.216
ENSG00000105339 E040 55.7394090 8.723784e-04 5.024935e-02 2.214898e-01 8 141178067 141178120 54 + 1.780 1.694 -0.289
ENSG00000105339 E041 73.8837890 6.977355e-04 3.842099e-04 7.072348e-03 8 141178121 141178196 76 + 1.930 1.797 -0.449
ENSG00000105339 E042 101.5206100 1.468077e-04 2.288333e-03 2.826060e-02 8 141180747 141180854 108 + 2.043 1.947 -0.321
ENSG00000105339 E043 3.9968679 3.688525e-03 1.574193e-01 4.240673e-01 8 141184488 141185138 651 + 0.534 0.726 0.836
ENSG00000105339 E044 129.9176313 1.559986e-04 4.688452e-02 2.126899e-01 8 141185139 141185278 140 + 2.123 2.067 -0.188
ENSG00000105339 E045 2.6307789 3.965735e-02 1.807324e-01 4.564562e-01 8 141185279 141185458 180 + 0.377 0.596 1.087
ENSG00000105339 E046 16.3016861 1.211769e-03 7.779585e-05 1.927350e-03 8 141188349 141188897 549 + 0.952 1.290 1.218
ENSG00000105339 E047 6.1769442 2.186780e-03 1.683772e-04 3.639782e-03 8 141188898 141188985 88 + 0.436 0.935 2.137
ENSG00000105339 E048 145.9635077 5.494376e-03 2.947436e-01 5.880110e-01 8 141188986 141189146 161 + 2.166 2.122 -0.147
ENSG00000105339 E049 5.7336895 3.014133e-03 2.909298e-01 5.844627e-01 8 141190166 141190283 118 + 0.712 0.838 0.502
ENSG00000105339 E050 111.2220515 1.839175e-04 5.652109e-03 5.410736e-02 8 141190284 141190417 134 + 2.074 1.991 -0.280
ENSG00000105339 E051 62.8403163 2.409317e-04 5.260567e-08 3.276252e-06 8 141190418 141191273 856 + 1.600 1.837 0.804
ENSG00000105339 E052 61.2981068 3.370938e-04 6.181476e-10 5.483417e-08 8 141191274 141191908 635 + 1.556 1.835 0.945
ENSG00000105339 E053 21.6054868 6.155533e-04 3.428505e-03 3.818939e-02 8 141191909 141191990 82 + 1.172 1.381 0.733
ENSG00000105339 E054 33.8004583 4.540996e-04 1.366731e-06 6.107145e-05 8 141191991 141192330 340 + 1.294 1.584 1.000
ENSG00000105339 E055 118.2215650 1.416415e-04 2.472261e-02 1.445441e-01 8 141192331 141192449 119 + 2.089 2.023 -0.221
ENSG00000105339 E056 2.8854923 5.528395e-03 8.966983e-02 3.111291e-01 8 141192450 141192525 76 + 0.377 0.632 1.248
ENSG00000105339 E057 95.8148851 3.055698e-04 9.988317e-01 1.000000e+00 8 141192526 141192663 138 + 1.956 1.955 -0.003
ENSG00000105339 E058 60.4165310 2.506558e-04 1.779325e-09 1.447453e-07 8 141192664 141193753 1090 + 1.556 1.827 0.919
ENSG00000105339 E059 13.7850087 9.761775e-04 5.415737e-01 7.892255e-01 8 141193754 141194032 279 + 1.106 1.156 0.179
ENSG00000105339 E060 1001.3978897 1.047737e-04 1.849093e-03 2.405426e-02 8 141194033 141195808 1776 + 2.950 2.979 0.096

Help

Please Click HERE to learn more details about the results from DEXseq.