ENSG00000105341

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000221943 ENSG00000105341 No_inf pgKDN_inf DMAC2 protein_coding protein_coding 19.82701 15.82781 21.46108 0.3116901 2.666973 0.4390217 8.4653517 10.444129 5.458238 0.5496628 2.1552966 -0.93492507 0.47223333 0.658875 0.312175 -0.346700 0.422934544 0.008336253 FALSE TRUE
ENST00000438807 ENSG00000105341 No_inf pgKDN_inf DMAC2 protein_coding protein_coding 19.82701 15.82781 21.46108 0.3116901 2.666973 0.4390217 3.2018973 2.140447 4.802780 0.9747901 1.8014786 1.16223367 0.15291667 0.137675 0.207750 0.070075 0.832690721 0.008336253 FALSE TRUE
ENST00000589503 ENSG00000105341 No_inf pgKDN_inf DMAC2 protein_coding retained_intron 19.82701 15.82781 21.46108 0.3116901 2.666973 0.4390217 2.5536128 2.491248 2.564414 0.4155853 0.3147156 0.04159641 0.13196667 0.156600 0.119725 -0.036875 0.848990913 0.008336253 FALSE TRUE
ENST00000592922 ENSG00000105341 No_inf pgKDN_inf DMAC2 protein_coding protein_coding 19.82701 15.82781 21.46108 0.3116901 2.666973 0.4390217 0.6524692 0.000000 1.210199 0.0000000 1.2101990 6.93097263 0.03171667 0.000000 0.052725 0.052725 0.860402546 0.008336253 FALSE TRUE
ENST00000594660 ENSG00000105341 No_inf pgKDN_inf DMAC2 protein_coding protein_coding 19.82701 15.82781 21.46108 0.3116901 2.666973 0.4390217 4.2078599 0.000000 6.682335 0.0000000 2.2828361 9.38636594 0.17403333 0.000000 0.277025 0.277025 0.008336253 0.008336253 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105341 E001 0.1265070 0.0122875396 0.643284211   19 41431318 41431318 1 - 0.000 0.088 9.181
ENSG00000105341 E002 1.6036126 0.0114769813 0.602669760 0.82660309 19 41431319 41431338 20 - 0.367 0.447 0.436
ENSG00000105341 E003 1.7218725 0.0627764768 0.824991848 0.93658929 19 41431339 41431352 14 - 0.414 0.447 0.173
ENSG00000105341 E004 47.3553313 0.0003770002 0.448739506 0.72267293 19 41431353 41431748 396 - 1.663 1.696 0.112
ENSG00000105341 E005 8.5299466 0.0506469796 0.286563664 0.58009701 19 41431749 41431755 7 - 0.899 1.029 0.484
ENSG00000105341 E006 19.5336238 0.0013564242 0.958190600 0.98998342 19 41431756 41431871 116 - 1.310 1.309 -0.005
ENSG00000105341 E007 8.4190952 0.0018132952 0.117613004 0.36229420 19 41431872 41431888 17 - 1.046 0.902 -0.535
ENSG00000105341 E008 15.4671611 0.0017394644 0.793698390 0.92135878 19 41431889 41431987 99 - 1.223 1.206 -0.058
ENSG00000105341 E009 44.2259930 0.0003613505 0.084668072 0.30062461 19 41431988 41432314 327 - 1.689 1.621 -0.234
ENSG00000105341 E010 19.1122625 0.0011422459 0.272101907 0.56590230 19 41432315 41432408 94 - 1.338 1.269 -0.242
ENSG00000105341 E011 4.7096417 0.0704226017 0.290454753 0.58404205 19 41432409 41432845 437 - 0.649 0.821 0.702
ENSG00000105341 E012 0.4879956 0.0161167220 0.862749800   19 41432846 41432853 8 - 0.185 0.161 -0.242
ENSG00000105341 E013 0.8429675 0.0125128740 0.171982064 0.44468482 19 41432854 41432928 75 - 0.367 0.161 -1.564
ENSG00000105341 E014 1.7984648 0.0079381464 0.006934276 0.06270845 19 41432929 41433062 134 - 0.623 0.224 -2.242
ENSG00000105341 E015 3.6664949 0.0039614765 0.403385639 0.68640210 19 41433063 41433223 161 - 0.721 0.618 -0.434
ENSG00000105341 E016 1.6056003 0.1057823057 0.697888793 0.87669293 19 41433224 41433271 48 - 0.368 0.447 0.436
ENSG00000105341 E017 6.1769625 0.0030399312 0.277210358 0.57058594 19 41433272 41433283 12 - 0.782 0.902 0.465
ENSG00000105341 E018 17.7220621 0.0050794596 0.089027131 0.30959316 19 41433284 41433434 151 - 1.332 1.212 -0.421
ENSG00000105341 E019 0.2455571 0.0162131370 0.892932461   19 41433440 41433536 97 - 0.102 0.088 -0.242
ENSG00000105341 E020 17.3914024 0.0009056216 0.220999307 0.50802901 19 41433537 41433626 90 - 1.305 1.224 -0.282
ENSG00000105341 E021 10.7297871 0.0028727963 0.425521752 0.70455241 19 41433627 41433673 47 - 1.025 1.096 0.261
ENSG00000105341 E022 7.4586768 0.0021177175 0.013203184 0.09629486 19 41436392 41436428 37 - 0.763 1.019 0.981
ENSG00000105341 E023 7.3432945 0.0024124107 0.003513925 0.03885200 19 41436429 41436472 44 - 0.721 1.029 1.185
ENSG00000105341 E024 7.1892132 0.0158081477 0.063293202 0.25310711 19 41438218 41438234 17 - 0.782 0.990 0.796
ENSG00000105341 E025 13.1441373 0.0129262488 0.908987714 0.97113908 19 41438235 41438414 180 - 1.139 1.155 0.056
ENSG00000105341 E026 0.6244140 0.1705764063 0.298612512 0.59163106 19 41438966 41439473 508 - 0.102 0.279 1.758
ENSG00000105341 E027 0.7436814 0.0140609214 0.542132296 0.78952755 19 41439474 41439881 408 - 0.185 0.279 0.758
ENSG00000105341 E028 1.8410226 0.0113170737 0.934230093 0.98106717 19 41439882 41440480 599 - 0.457 0.447 -0.049
ENSG00000105341 E029 0.0000000       19 41440481 41440717 237 -      

Help

Please Click HERE to learn more details about the results from DEXseq.