ENSG00000105464

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263269 ENSG00000105464 No_inf pgKDN_inf GRIN2D protein_coding protein_coding 20.21261 12.5358 22.18366 0.1653322 0.3410846 0.8229437 0.9899867 1.9144358 0.2050156 0.3035900 0.1062911 -3.161922 0.06463333 0.151975 0.009250 -0.142725 0.002924098 0.002924098 FALSE TRUE
MSTRG.15411.2 ENSG00000105464 No_inf pgKDN_inf GRIN2D protein_coding   20.21261 12.5358 22.18366 0.1653322 0.3410846 0.8229437 16.7570886 9.8339189 20.6115628 0.5533028 0.7729341 1.066849 0.82733333 0.785300 0.929325 0.144025 0.213727106 0.002924098 FALSE TRUE
MSTRG.15411.5 ENSG00000105464 No_inf pgKDN_inf GRIN2D protein_coding   20.21261 12.5358 22.18366 0.1653322 0.3410846 0.8229437 1.3070093 0.6188066 1.3670809 0.3838520 0.7298797 1.130925 0.06176667 0.049375 0.061425 0.012050 0.933965972 0.002924098 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105464 E001 2.158240 0.0067105892 6.373480e-08 3.877740e-06 19 48393668 48393868 201 + 0.000 0.791 13.241
ENSG00000105464 E002 5.940481 0.0028157071 6.931624e-15 1.161025e-12 19 48394658 48394936 279 + 0.202 1.158 4.503
ENSG00000105464 E003 1.888794 0.0078206728 1.978022e-04 4.144626e-03 19 48398367 48398857 491 + 0.144 0.695 3.329
ENSG00000105464 E004 1.088024 0.0124428853 6.908565e-01 8.731056e-01 19 48399087 48399107 21 + 0.339 0.282 -0.371
ENSG00000105464 E005 3.730746 0.0040475246 1.039714e-01 3.369429e-01 19 48399108 48399145 38 + 0.743 0.536 -0.895
ENSG00000105464 E006 33.278878 0.0004377602 3.538150e-02 1.800563e-01 19 48404734 48405353 620 + 1.566 1.467 -0.340
ENSG00000105464 E007 14.309170 0.0011952746 4.494241e-01 7.231560e-01 19 48413991 48414105 115 + 1.198 1.149 -0.174
ENSG00000105464 E008 6.758316 0.0020925649 1.428710e-01 4.023791e-01 19 48414373 48414380 8 + 0.938 0.791 -0.569
ENSG00000105464 E009 20.092153 0.0008385129 1.419228e-01 4.008412e-01 19 48414381 48414584 204 + 1.351 1.264 -0.307
ENSG00000105464 E010 1.352934 0.0205896503 3.378145e-01 6.296111e-01 19 48414846 48414863 18 + 0.298 0.451 0.892
ENSG00000105464 E011 22.300018 0.0034695088 3.796176e-01 6.662425e-01 19 48414864 48415032 169 + 1.332 1.399 0.232
ENSG00000105464 E012 24.655413 0.0159244499 1.645544e-01 4.337981e-01 19 48416002 48416155 154 + 1.351 1.467 0.400
ENSG00000105464 E013 24.433228 0.0005825291 4.755100e-02 2.143860e-01 19 48419234 48419359 126 + 1.440 1.330 -0.382
ENSG00000105464 E014 32.414140 0.0009971410 5.816411e-01 8.136357e-01 19 48419585 48419814 230 + 1.525 1.506 -0.065
ENSG00000105464 E015 5.683363 0.0026094427 4.165809e-01 6.964317e-01 19 48421785 48421790 6 + 0.851 0.769 -0.325
ENSG00000105464 E016 16.786924 0.0069073384 6.293315e-01 8.409767e-01 19 48421791 48421892 102 + 1.224 1.271 0.165
ENSG00000105464 E017 10.710282 0.0013336289 6.739926e-01 8.649499e-01 19 48421893 48421945 53 + 1.043 1.089 0.166
ENSG00000105464 E018 19.287878 0.0007633470 3.816662e-01 6.680768e-01 19 48441769 48441956 188 + 1.320 1.271 -0.172
ENSG00000105464 E019 27.932035 0.0005752785 2.718332e-02 1.532712e-01 19 48442150 48442382 233 + 1.498 1.383 -0.399
ENSG00000105464 E020 221.616927 0.0001055502 3.694575e-01 6.576297e-01 19 48442600 48444980 2381 + 2.330 2.355 0.081

Help

Please Click HERE to learn more details about the results from DEXseq.