ENSG00000105483

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000377461 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding retained_intron 56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 2.3275870 5.711478 0.0000000 0.8178794 0.0000000 -9.16024399 0.03691667 0.090925 0.000000 -0.090925 2.459518e-08 2.459518e-08 FALSE  
ENST00000519332 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding protein_coding 56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 3.7024762 3.651104 3.5306352 2.1481599 2.1516781 -0.04827063 0.06225000 0.056500 0.052450 -0.004050 1.000000e+00 2.459518e-08    
ENST00000520753 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding protein_coding 56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 0.8090117 0.000000 2.4270351 0.0000000 0.9065703 7.92898320 0.01826667 0.000000 0.054800 0.054800 4.405302e-02 2.459518e-08 FALSE  
ENST00000651546 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding protein_coding 56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 2.9940799 4.281649 0.6419507 1.6091852 0.4411959 -2.71869740 0.05686667 0.068100 0.010850 -0.057250 4.785674e-01 2.459518e-08 FALSE  
MSTRG.15431.11 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding   56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 3.2972378 4.504638 3.5916856 1.4475834 1.4275734 -0.32593802 0.05671667 0.074150 0.063175 -0.010975 8.996922e-01 2.459518e-08    
MSTRG.15431.12 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding   56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 0.8874932 0.000000 2.6624795 0.0000000 2.6624795 8.06203509 0.02420000 0.000000 0.072600 0.072600 8.463425e-01 2.459518e-08 FALSE  
MSTRG.15431.14 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding   56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 3.0321646 3.815664 1.3739589 1.8386071 0.7948777 -1.46690923 0.05305833 0.062050 0.027850 -0.034200 8.229988e-01 2.459518e-08 FALSE  
MSTRG.15431.15 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding   56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 9.4010358 9.627477 11.8212422 1.0642112 1.2839527 0.29587421 0.17543333 0.155500 0.226225 0.070725 6.944012e-01 2.459518e-08 FALSE  
MSTRG.15431.16 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding   56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 4.4680082 7.136182 3.5297850 1.1545962 1.3113665 -1.01351101 0.08460833 0.113025 0.072975 -0.040050 8.101558e-01 2.459518e-08 FALSE  
MSTRG.15431.45 ENSG00000105483 No_inf pgKDN_inf CARD8 protein_coding   56.78263 62.65573 55.60798 2.681802 8.814656 -0.1721254 5.8262702 0.000000 6.2610143 0.0000000 6.2610143 9.29255501 0.08514167 0.000000 0.078950 0.078950 8.299072e-01 2.459518e-08    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105483 E001 2.5042432 0.0057507444 7.414018e-02 2.774587e-01 19 48180770 48183092 2323 - 0.348 0.615 1.346
ENSG00000105483 E002 0.0000000       19 48186550 48186765 216 -      
ENSG00000105483 E003 0.3703650 0.0165205219 9.183325e-01   19 48187678 48187770 93 - 0.116 0.143 0.346
ENSG00000105483 E004 0.3727544 0.0165928647 9.182197e-01   19 48189443 48189565 123 - 0.116 0.143 0.346
ENSG00000105483 E005 0.4977836 0.0294584547 5.890492e-01   19 48190496 48190600 105 - 0.116 0.200 0.931
ENSG00000105483 E006 0.0000000       19 48191914 48191982 69 -      
ENSG00000105483 E007 0.2536433 0.0160010880 4.432496e-01   19 48193017 48193181 165 - 0.000 0.143 10.958
ENSG00000105483 E008 1.2611677 0.0108363757 4.277236e-02 2.015979e-01 19 48203146 48203631 486 - 0.116 0.440 2.516
ENSG00000105483 E009 1.1076620 0.0109508651 7.325799e-01 8.937031e-01 19 48203632 48203843 212 - 0.348 0.296 -0.332
ENSG00000105483 E010 0.8617267 0.0128746064 8.274042e-01 9.375103e-01 19 48203844 48204243 400 - 0.284 0.251 -0.239
ENSG00000105483 E011 1.1331844 0.1685310647 1.219065e-01 3.693951e-01 19 48206384 48206520 137 - 0.116 0.408 2.345
ENSG00000105483 E012 1.1149607 0.1520192382 7.955116e-01 9.223427e-01 19 48208086 48208089 4 - 0.283 0.337 0.346
ENSG00000105483 E013 2.1311707 0.1514202257 1.475196e-01 4.088974e-01 19 48208090 48208103 14 - 0.283 0.572 1.569
ENSG00000105483 E014 2.0039084 0.1620945757 1.921288e-01 4.719438e-01 19 48208104 48208118 15 - 0.283 0.549 1.462
ENSG00000105483 E015 2.7498578 0.0055086557 1.127341e-01 3.532124e-01 19 48208119 48208147 29 - 0.404 0.635 1.111
ENSG00000105483 E016 69.0585555 0.0003493810 3.469706e-01 6.375766e-01 19 48208148 48209643 1496 - 1.851 1.818 -0.112
ENSG00000105483 E017 6.8536078 0.0296936542 9.382395e-02 3.185357e-01 19 48209644 48209667 24 - 0.996 0.797 -0.758
ENSG00000105483 E018 111.8823216 0.0002030093 7.247276e-02 2.732046e-01 19 48209668 48210486 819 - 2.068 2.019 -0.167
ENSG00000105483 E019 73.4913044 0.0003242569 1.621970e-01 4.306568e-01 19 48210487 48210786 300 - 1.824 1.876 0.174
ENSG00000105483 E020 19.9437330 0.0026280007 2.699281e-01 5.635545e-01 19 48210787 48210789 3 - 1.352 1.278 -0.260
ENSG00000105483 E021 108.1601206 0.0001428243 3.598437e-01 6.493618e-01 19 48210790 48211151 362 - 2.039 2.014 -0.084
ENSG00000105483 E022 64.4377698 0.0004336668 1.758855e-01 4.499932e-01 19 48211152 48211376 225 - 1.832 1.782 -0.170
ENSG00000105483 E023 64.0009656 0.0002400682 5.896297e-01 8.182870e-01 19 48211377 48211565 189 - 1.784 1.806 0.074
ENSG00000105483 E024 31.7558717 0.0004518425 6.375361e-01 8.453772e-01 19 48211566 48211616 51 - 1.484 1.511 0.092
ENSG00000105483 E025 68.4171418 0.0061657258 2.707183e-01 5.643838e-01 19 48211617 48211826 210 - 1.791 1.847 0.188
ENSG00000105483 E026 34.4571855 0.0004791865 9.787930e-01 9.971889e-01 19 48211827 48211896 70 - 1.534 1.536 0.009
ENSG00000105483 E027 35.3059934 0.0021645589 9.050417e-01 9.695450e-01 19 48211897 48211975 79 - 1.549 1.543 -0.019
ENSG00000105483 E028 1.4868993 0.1271958793 7.857225e-01 9.174837e-01 19 48215138 48215339 202 - 0.348 0.408 0.346
ENSG00000105483 E029 25.2873394 0.0013773360 1.140972e-01 3.556858e-01 19 48215340 48215384 45 - 1.340 1.440 0.346
ENSG00000105483 E030 34.0579617 0.0143860442 3.042470e-01 5.977001e-01 19 48218871 48219012 142 - 1.480 1.558 0.267
ENSG00000105483 E031 42.0376021 0.0030829678 3.771259e-01 6.641729e-01 19 48221730 48221855 126 - 1.646 1.602 -0.150
ENSG00000105483 E032 8.0586842 0.0017207270 4.141788e-01 6.945346e-01 19 48223719 48223868 150 - 0.890 0.973 0.313
ENSG00000105483 E033 58.0808046 0.0002603374 3.266272e-01 6.190066e-01 19 48230438 48230697 260 - 1.780 1.742 -0.128
ENSG00000105483 E034 8.8346545 0.0016385342 1.504641e-01 4.130761e-01 19 48230698 48230700 3 - 1.058 0.925 -0.494
ENSG00000105483 E035 0.7451005 0.3518280244 8.362721e-01 9.412876e-01 19 48230701 48230776 76 - 0.208 0.251 0.345
ENSG00000105483 E036 45.5664776 0.0006171214 1.266564e-01 3.772767e-01 19 48230777 48231006 230 - 1.695 1.627 -0.230
ENSG00000105483 E037 0.3727544 0.0165928647 9.182197e-01   19 48231007 48231068 62 - 0.116 0.143 0.346
ENSG00000105483 E038 24.0142559 0.0005833120 2.829426e-01 5.766296e-01 19 48231660 48231728 69 - 1.423 1.359 -0.222
ENSG00000105483 E039 22.1345171 0.0006882815 1.650494e-01 4.345720e-01 19 48231729 48231810 82 - 1.402 1.316 -0.300
ENSG00000105483 E040 3.1533977 0.0478980024 1.559668e-03 2.106138e-02 19 48231811 48232114 304 - 0.208 0.739 2.869
ENSG00000105483 E041 14.0879499 0.0010179551 2.018269e-02 1.277621e-01 19 48232453 48232493 41 - 1.267 1.090 -0.629
ENSG00000105483 E042 24.0174349 0.0006217725 4.340878e-08 2.735058e-06 19 48232494 48232789 296 - 1.113 1.489 1.318
ENSG00000105483 E043 31.3156797 0.0007057545 1.388054e-06 6.176839e-05 19 48232790 48233271 482 - 1.295 1.581 0.985
ENSG00000105483 E044 12.8313009 0.0010805648 7.589213e-03 6.664687e-02 19 48233272 48233404 133 - 0.968 1.199 0.839
ENSG00000105483 E045 4.6077523 0.0040756030 1.382690e-01 3.956295e-01 19 48233405 48233409 5 - 0.610 0.797 0.779
ENSG00000105483 E046 30.7954090 0.0008796026 1.220547e-02 9.153130e-02 19 48233410 48233820 411 - 1.392 1.536 0.497
ENSG00000105483 E047 7.4560096 0.0050585753 1.686182e-01 4.399310e-01 19 48233821 48233845 25 - 0.815 0.964 0.568
ENSG00000105483 E048 15.8967526 0.0064568535 7.016413e-02 2.680997e-01 19 48233846 48233980 135 - 1.113 1.264 0.536
ENSG00000105483 E049 19.7072374 0.0007536833 1.138870e-01 3.553589e-01 19 48233981 48234277 297 - 1.230 1.340 0.387
ENSG00000105483 E050 11.1879533 0.0214030246 9.588740e-02 3.225101e-01 19 48234278 48234402 125 - 0.953 1.130 0.645
ENSG00000105483 E051 20.1921632 0.0006864756 1.717410e-03 2.268596e-02 19 48234403 48234471 69 - 1.428 1.225 -0.707
ENSG00000105483 E052 17.2377151 0.0008899644 1.962115e-03 2.519636e-02 19 48234472 48234543 72 - 1.370 1.154 -0.757
ENSG00000105483 E053 0.9970461 0.0199997045 4.181359e-01 6.977875e-01 19 48234544 48234669 126 - 0.208 0.337 0.931
ENSG00000105483 E054 0.7076830 0.0135191055 1.819109e-03 2.372716e-02 19 48238262 48238333 72 - 0.454 0.000 -14.123
ENSG00000105483 E055 0.9702001 0.0413886442 1.901205e-01 4.691599e-01 19 48238334 48238335 2 - 0.404 0.200 -1.392
ENSG00000105483 E056 2.8152505 0.0094293223 2.054234e-01 4.886662e-01 19 48238336 48238382 47 - 0.671 0.498 -0.780
ENSG00000105483 E057 22.4861691 0.0006248337 5.132783e-02 2.245005e-01 19 48238383 48238474 92 - 1.428 1.308 -0.417
ENSG00000105483 E058 17.9637781 0.0205032476 2.628411e-01 5.556412e-01 19 48238475 48238526 52 - 1.322 1.225 -0.337
ENSG00000105483 E059 9.2041860 0.0029056133 1.128257e-01 3.533839e-01 19 48238527 48238532 6 - 1.081 0.935 -0.539
ENSG00000105483 E060 23.3128739 0.0181247572 7.447188e-02 2.782832e-01 19 48240962 48241063 102 - 1.457 1.312 -0.502
ENSG00000105483 E061 12.5431974 0.0118436561 1.357927e-01 3.917123e-01 19 48241553 48242539 987 - 1.022 1.166 0.521
ENSG00000105483 E062 4.2884882 0.0035151413 2.460559e-01 5.366884e-01 19 48242540 48242644 105 - 0.794 0.654 -0.572
ENSG00000105483 E063 4.1841737 0.0038834385 5.322165e-01 7.826313e-01 19 48246075 48246381 307 - 0.749 0.673 -0.313
ENSG00000105483 E064 13.6580331 0.0024457593 3.508337e-01 6.410934e-01 19 48249523 48249633 111 - 1.197 1.124 -0.262
ENSG00000105483 E065 0.3809057 0.0158381757 2.259588e-01   19 48249634 48249750 117 - 0.000 0.200 11.512
ENSG00000105483 E066 10.2212720 0.0162719493 5.706858e-01 8.070524e-01 19 48249751 48249847 97 - 1.070 1.016 -0.198
ENSG00000105483 E067 1.9779412 0.0081756888 9.163586e-01 9.737077e-01 19 48249848 48249878 31 - 0.454 0.470 0.083
ENSG00000105483 E068 0.5077596 0.0150305552 1.196747e-01 3.656339e-01 19 48249879 48249883 5 - 0.000 0.251 11.903
ENSG00000105483 E069 0.0000000       19 48252173 48252208 36 -      
ENSG00000105483 E070 1.6065115 0.0087262496 9.801990e-01 9.977739e-01 19 48255792 48255946 155 - 0.404 0.408 0.024

Help

Please Click HERE to learn more details about the results from DEXseq.