ENSG00000105486

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263274 ENSG00000105486 No_inf pgKDN_inf LIG1 protein_coding protein_coding 16.6298 21.05094 12.13157 0.9996116 0.5672777 -0.7946146 0.9955885 0.000000 2.9867654 0.0000000 0.9965422 8.2272623 0.08022500 0.000000 0.240675 0.240675 0.007729487 0.007729487 FALSE TRUE
ENST00000599322 ENSG00000105486 No_inf pgKDN_inf LIG1 protein_coding retained_intron 16.6298 21.05094 12.13157 0.9996116 0.5672777 -0.7946146 2.2850474 1.267506 0.9717282 1.2675061 0.5610348 -0.3799346 0.12280833 0.055200 0.074125 0.018925 0.777754065 0.007729487   FALSE
ENST00000601091 ENSG00000105486 No_inf pgKDN_inf LIG1 protein_coding nonsense_mediated_decay 16.6298 21.05094 12.13157 0.9996116 0.5672777 -0.7946146 1.5179547 2.786859 0.5151082 0.9486074 0.2984626 -2.4131209 0.08794167 0.135075 0.042825 -0.092250 0.741086988 0.007729487 TRUE TRUE
ENST00000699865 ENSG00000105486 No_inf pgKDN_inf LIG1 protein_coding retained_intron 16.6298 21.05094 12.13157 0.9996116 0.5672777 -0.7946146 1.6370318 4.341706 0.4048515 0.9904827 0.2417426 -3.3909142 0.08420833 0.209450 0.034350 -0.175100 0.113798485 0.007729487   FALSE
ENST00000699868 ENSG00000105486 No_inf pgKDN_inf LIG1 protein_coding protein_coding 16.6298 21.05094 12.13157 0.9996116 0.5672777 -0.7946146 1.7037614 0.000000 0.9912502 0.0000000 0.9912502 6.6456587 0.13392500 0.000000 0.089700 0.089700 0.818466665 0.007729487 FALSE TRUE
MSTRG.15427.5 ENSG00000105486 No_inf pgKDN_inf LIG1 protein_coding   16.6298 21.05094 12.13157 0.9996116 0.5672777 -0.7946146 3.8523108 5.744151 3.6748660 0.9857478 0.5923651 -0.6429910 0.22673333 0.274300 0.305350 0.031050 0.936428608 0.007729487 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105486 E001 0.0000000       19 48115445 48115445 1 -      
ENSG00000105486 E002 0.0000000       19 48115446 48115446 1 -      
ENSG00000105486 E003 0.0000000       19 48115447 48115448 2 -      
ENSG00000105486 E004 0.2536433 0.0158763078 4.404509e-01   19 48115449 48115449 1 - 0.000 0.144 9.685
ENSG00000105486 E005 0.4909196 0.0187671697 6.583207e-01   19 48115450 48115454 5 - 0.207 0.144 -0.638
ENSG00000105486 E006 0.6180559 0.1247831630 9.838955e-01 9.986907e-01 19 48115455 48115459 5 - 0.207 0.201 -0.053
ENSG00000105486 E007 0.6180559 0.1247831630 9.838955e-01 9.986907e-01 19 48115460 48115467 8 - 0.207 0.201 -0.053
ENSG00000105486 E008 0.8714169 0.0264420716 5.698654e-01 8.067383e-01 19 48115468 48115491 24 - 0.207 0.297 0.684
ENSG00000105486 E009 0.7445629 0.1751022046 7.774016e-01 9.145682e-01 19 48115492 48115496 5 - 0.207 0.252 0.361
ENSG00000105486 E010 0.7445629 0.1751022046 7.774016e-01 9.145682e-01 19 48115497 48115523 27 - 0.207 0.252 0.361
ENSG00000105486 E011 14.8831046 0.0010542563 1.990548e-01 4.805649e-01 19 48115524 48115732 209 - 1.121 1.223 0.362
ENSG00000105486 E012 12.1143841 0.0011719159 8.088748e-01 9.294229e-01 19 48115873 48115965 93 - 1.090 1.113 0.083
ENSG00000105486 E013 0.2537694 0.0158929145 4.403155e-01   19 48115966 48116174 209 - 0.000 0.144 12.304
ENSG00000105486 E014 17.7949498 0.0008279918 7.184871e-01 8.867152e-01 19 48117638 48117781 144 - 1.243 1.271 0.099
ENSG00000105486 E015 1.3527415 0.1859929811 6.517792e-01 8.533477e-01 19 48117782 48117880 99 - 0.403 0.338 -0.374
ENSG00000105486 E016 5.7019104 0.0025159014 3.754977e-01 6.630170e-01 19 48119137 48119190 54 - 0.747 0.850 0.410
ENSG00000105486 E017 3.0286494 0.0048568259 6.814718e-04 1.111079e-02 19 48119191 48119513 323 - 0.207 0.726 2.822
ENSG00000105486 E018 16.5681107 0.0008476405 4.580893e-09 3.445829e-07 19 48120167 48121169 1003 - 0.870 1.358 1.764
ENSG00000105486 E019 0.6001170 0.0151545950 6.410330e-02 2.549683e-01 19 48121170 48121271 102 - 0.347 0.078 -2.638
ENSG00000105486 E020 3.2110414 0.0046832507 9.631229e-01 9.921323e-01 19 48121272 48121322 51 - 0.608 0.617 0.040
ENSG00000105486 E021 8.4693519 0.0032251836 2.123893e-01 4.976031e-01 19 48122934 48123016 83 - 1.032 0.917 -0.428
ENSG00000105486 E022 9.8155536 0.0014777767 1.176010e-01 3.622942e-01 19 48123174 48123318 145 - 1.100 0.966 -0.493
ENSG00000105486 E023 0.3709916 0.0164064874 9.147124e-01   19 48123319 48123353 35 - 0.116 0.144 0.362
ENSG00000105486 E024 1.2512260 0.0106533098 2.028417e-01 4.854146e-01 19 48123354 48123623 270 - 0.207 0.410 1.362
ENSG00000105486 E025 1.1059904 0.0111777148 7.376749e-01 8.959078e-01 19 48126772 48127276 505 - 0.347 0.297 -0.316
ENSG00000105486 E026 0.0000000       19 48127277 48127348 72 -      
ENSG00000105486 E027 9.3611498 0.0030676589 5.777925e-01 8.113163e-01 19 48127910 48128020 111 - 1.032 0.984 -0.178
ENSG00000105486 E028 13.1644243 0.0012955290 3.858281e-01 6.716780e-01 19 48131076 48131171 96 - 1.177 1.113 -0.231
ENSG00000105486 E029 13.8115023 0.0011341830 7.841425e-01 9.168342e-01 19 48132982 48133097 116 - 1.168 1.151 -0.064
ENSG00000105486 E030 1.1333735 0.0407698199 7.426742e-02 2.777959e-01 19 48133098 48133494 397 - 0.116 0.410 2.362
ENSG00000105486 E031 0.1272623 0.0123514011 8.720621e-01   19 48133630 48133761 132 - 0.000 0.078 11.399
ENSG00000105486 E032 10.9791234 0.0014050830 7.676805e-01 9.100916e-01 19 48133981 48134066 86 - 1.079 1.057 -0.080
ENSG00000105486 E033 10.1959214 0.0014236987 2.018364e-01 4.842242e-01 19 48135680 48135779 100 - 1.100 0.993 -0.394
ENSG00000105486 E034 3.4364898 0.0113161232 4.362586e-01 7.127243e-01 19 48136034 48136043 10 - 0.696 0.596 -0.431
ENSG00000105486 E035 4.8083358 0.0147895659 8.032319e-01 9.269012e-01 19 48136044 48136125 82 - 0.770 0.741 -0.114
ENSG00000105486 E036 5.1033668 0.0455793822 2.757019e-01 5.692625e-01 19 48137008 48137084 77 - 0.669 0.825 0.635
ENSG00000105486 E037 10.1565632 0.0037130065 5.171693e-01 7.727023e-01 19 48137522 48137662 141 - 0.994 1.057 0.232
ENSG00000105486 E038 3.7139188 0.0425943730 8.319825e-01 9.392783e-01 19 48137663 48137688 26 - 0.639 0.675 0.150
ENSG00000105486 E039 0.4896948 0.0161702924 6.541375e-01   19 48137689 48137759 71 - 0.207 0.144 -0.638
ENSG00000105486 E040 6.5796013 0.0478625339 3.092057e-01 6.025520e-01 19 48137760 48139540 1781 - 0.770 0.917 0.572
ENSG00000105486 E041 11.2279154 0.0212745280 9.171371e-01 9.739672e-01 19 48139971 48140143 173 - 1.079 1.072 -0.026
ENSG00000105486 E042 0.0000000       19 48143309 48143342 34 -      
ENSG00000105486 E043 5.1417414 0.0028409424 1.488889e-01 4.109694e-01 19 48143543 48143599 57 - 0.870 0.709 -0.638
ENSG00000105486 E044 0.2441377 0.0160639203 7.257854e-01   19 48143600 48143877 278 - 0.116 0.078 -0.638
ENSG00000105486 E045 0.0000000       19 48143878 48143882 5 -      
ENSG00000105486 E046 6.5585072 0.0239710501 6.533172e-01 8.542733e-01 19 48143883 48143963 81 - 0.833 0.885 0.202
ENSG00000105486 E047 5.5802900 0.1252296463 6.209718e-01 8.363046e-01 19 48149763 48149802 40 - 0.747 0.838 0.363
ENSG00000105486 E048 3.6907708 0.1896371329 7.415027e-01 8.975114e-01 19 48149803 48149809 7 - 0.696 0.637 -0.249
ENSG00000105486 E049 3.7904314 0.0858711192 2.921564e-01 5.856375e-01 19 48149810 48149825 16 - 0.770 0.596 -0.730
ENSG00000105486 E050 3.6729820 0.0042141771 2.234496e-01 5.110913e-01 19 48149826 48149841 16 - 0.747 0.596 -0.638
ENSG00000105486 E051 8.3793767 0.0040763988 7.180183e-01 8.865142e-01 19 48150088 48150207 120 - 0.980 0.947 -0.123
ENSG00000105486 E052 3.3401895 0.0044933032 8.378453e-01 9.419273e-01 19 48150208 48150210 3 - 0.608 0.637 0.128
ENSG00000105486 E053 7.4029488 0.0019171351 8.660744e-01 9.538486e-01 19 48151232 48151336 105 - 0.921 0.907 -0.053
ENSG00000105486 E054 1.7041946 0.0984595214 2.135020e-01 4.987365e-01 19 48151337 48151339 3 - 0.537 0.338 -1.053
ENSG00000105486 E055 0.1187032 0.0119014507 3.361663e-01   19 48151340 48151385 46 - 0.116 0.000 -13.121
ENSG00000105486 E056 0.2533610 0.0159758782 4.407863e-01   19 48151468 48151734 267 - 0.000 0.144 12.304
ENSG00000105486 E057 3.3089460 0.0046926936 3.338639e-01 6.257940e-01 19 48153872 48153900 29 - 0.696 0.574 -0.531
ENSG00000105486 E058 4.6619050 0.0039415499 2.955267e-01 5.886983e-01 19 48153901 48153967 67 - 0.813 0.692 -0.486
ENSG00000105486 E059 0.1268540 0.0122511610 8.721941e-01   19 48153968 48154207 240 - 0.000 0.078 11.399
ENSG00000105486 E060 0.0000000       19 48154393 48154564 172 -      
ENSG00000105486 E061 6.5505455 0.0023401554 8.582523e-01 9.505500e-01 19 48157014 48157140 127 - 0.852 0.874 0.085
ENSG00000105486 E062 0.0000000       19 48161174 48161371 198 -      
ENSG00000105486 E063 4.3194643 0.0273098285 9.017505e-01 9.684391e-01 19 48161372 48161437 66 - 0.722 0.709 -0.053
ENSG00000105486 E064 5.0522848 0.0284258955 7.412657e-01 8.973669e-01 19 48161438 48161507 70 - 0.792 0.757 -0.141
ENSG00000105486 E065 3.2120467 0.0045441834 9.618551e-01 9.916848e-01 19 48162262 48162283 22 - 0.608 0.617 0.040
ENSG00000105486 E066 5.1624529 0.0038988320 4.136587e-01 6.943494e-01 19 48162284 48162351 68 - 0.833 0.741 -0.362
ENSG00000105486 E067 0.2542726 0.2415861593 4.988450e-01   19 48163983 48165549 1567 - 0.000 0.144 12.123
ENSG00000105486 E068 4.2344434 0.0039405605 1.538525e-03 2.086468e-02 19 48165550 48165623 74 - 0.904 0.526 -1.576
ENSG00000105486 E069 0.0000000       19 48169609 48169689 81 -      
ENSG00000105486 E070 0.0000000       19 48169974 48170058 85 -      
ENSG00000105486 E071 0.0000000       19 48170059 48170240 182 -      
ENSG00000105486 E072 3.0372843 0.0736321330 8.106116e-02 2.925317e-01 19 48170241 48170603 363 - 0.747 0.472 -1.223

Help

Please Click HERE to learn more details about the results from DEXseq.